Michael Jonathan Davies
Michael Jonathan Davies

Professor


  1. 2018
  2. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, Luke Dean, Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  3. Published

    Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)

    Khramtsov, V. V. & Davies, Michael Jonathan, 2018, In : Free Radical Research. 52, 3, p. 305-306

    Research output: Contribution to journalEditorialResearch

  4. 2017
  5. Published

    Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins

    Carroll, Luke Dean, Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 132-142 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

    Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, Luke Dean, Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications

    Rykær, M., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 3 Nov 2017, In : Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

    Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, P. & Davies, Michael Jonathan, Nov 2017, In : Free Radical Biology & Medicine. 112, p. 240-252 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function

    Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Cardiac spheroids as promising in vitro models to study the human heart microenvironment

    Polonchuk, L., Chabria, M., Badi, L., Hoflack, J., Figtree, G. A., Davies, Michael Jonathan & Gentile, C., 1 Aug 2017, In : Scientific Reports. 7, 12 p., 7005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1

    Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

    Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael Jonathan, Svensson, B., Harris, P. & Hägglund, P., Apr 2017, In : Scientific Reports. 7, 10 p., 46282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma

    Havelund, J. F., Wojdyla, K. I., Davies, Michael Jonathan, Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In : Journal of Proteomics. 156, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification

    Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress

    Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael Jonathan, Schiesser, C. H. & Parry, L. J., Mar 2017, In : Biochemical Pharmacology. 128, p. 34-45 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes

    Carroll, Luke Dean, Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, 2017, In : Redox Biology. 12, p. 872-882 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin

    Krämer, Anna Carola, Torreggiani, A. & Davies, Michael Jonathan, 2017, In : Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function

    Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael Jonathan, Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In : Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space

    Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael Jonathan, Clair, D. K. S. & Mukai, C., 16 Dec 2016, In : Scientific Reports. 6, 10 p., 39015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability

    Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)

    Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael Jonathan, 2 Oct 2016, In : Free Radical Research. 50, 10, p. 1045-1046

    Research output: Contribution to journalEditorialResearch

  24. Published

    Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

    Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael Jonathan, Oct 2016, In : Free Radical Research. 50, 10, p. 1116-1130 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

    Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael Jonathan, Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In : World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael Jonathan, Aug 2016, In : Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues

    Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

    Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : Free Radical Biology & Medicine. 94, p. 88-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies

    Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael Jonathan, Ozawa, T. & St. Clair, D., 2016, In : Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Competitive kinetics as a tool to determine rate constants for reduction of ferrylmyoglobin by food components

    Jongberg, S., Lund, Marianne N., Pattison, D. I., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2016, In : Food Chemistry. 199, p. 36-41 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

    Davies, Michael Jonathan, 2016, In : Methods. 109, p. 21-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells

    Talib, J. & Davies, Michael Jonathan, 2016, In : Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin

    Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin

    Krämer, Anna Carola, Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael Jonathan, 2016, In : Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2016, In : RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Protein oxidation and peroxidation

    Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

    Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

    Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2015
  40. Published

    Temperature Activated Diffusion of Radicals through Ion Implanted Polymers

    Wakelin, E. A., Davies, Michael Jonathan, Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In : A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance

    Storkey, C., Pattison, D. I., Ignasiak, M. T., Schiesser, C. H. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 1049-1056 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

    Weber, D., Davies, Michael Jonathan & Grune, T., 1 Aug 2015, In : Redox Biology. 5, p. 367-380 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion

    Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael Jonathan, Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In : Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage

    Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): implications for foam cell formation in atherosclerosis

    Ismael, F. O., Proudfoot, J. M., Brown, B. E., van Reyk, D. M., Croft, K. D., Davies, Michael Jonathan & Hawkins, C. L., May 2015, In : Archives of Biochemistry and Biophysics. 573, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice

    Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael Jonathan, May 2015, In : Atherosclerosis. 240, 1, p. 234-241 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

    Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In : Free Radical Research. 49, 4, p. 347-73 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In : Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In : British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants

    Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Sulfur and selenium in oxidation protection

    Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54

    Research output: Contribution to journalReviewResearchpeer-review

  53. 2014
  54. Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants

    Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In : Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In : Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205