Michael J. Davies

Michael J. Davies

Professor


  1. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael J., 15 Apr 2007, In: Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael J., 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

    Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael J., 15 Jul 2010, In: Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)

    Khramtsov, V. V. & Davies, Michael J., 2018, In: Free Radical Research. 52, 3, p. 305-306

    Research output: Contribution to journalEditorial

  5. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial

    Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael J., 1 Dec 2008, In: Diabetic Medicine. 25, 12, p. 1454-1461 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael J., 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

    Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael J., 1 Apr 2010, In: Primary Care Diabetes. 4, 1, p. 25-32 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice

    Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael J., May 2015, In: Atherosclerosis. 240, 1, p. 234-241 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael J. & Dean, R. T., 15 Apr 2002, In: Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael J. & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations

    Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 15 Apr 2010, In: Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1

    Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael J., Wink, D. A. & Richardson, D. R., May 2017, In: B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.

    Research output: Contribution to journalReviewpeer-review

  13. Published

    Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin

    Krämer, A. C., Torreggiani, A. & Davies, Michael J., 2017, In: Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin

    Krämer, A. C. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Key role of cysteine residues and sulfenic acids in thermal- and H2O2-mediated modification of β-lactoglobulin

    Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael J., 2016, In: Free Radical Biology & Medicine. 97, 8, p. 544–555 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Key role of cysteine residues in thermal- and H2O2-mediated modification of beta-lactoglobulin

    Krämer, A. C., Thulstrup, Peter Waaben, Lund, Marianne N. & Davies, Michael J., 2016, In: Free Radical Biology & Medicine. 96, Suppl. 1, p. S16 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  17. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals

    Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael J., Nov 2008, In: Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael J., 2008, In: Biochemical Journal. 410, 3, p. 565-574

    Research output: Contribution to journalJournal articlepeer-review

  19. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, S. H., Lindemose, Søren, Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael J., 2020, In: Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

    Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, Per Mårten & Davies, Michael J., Nov 2017, In: Free Radical Biology & Medicine. 112, p. 240-252 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals

    Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael J., Oct 2018, In: Free Radical Biology and Medicine. 126, p. 73-86

    Research output: Contribution to journalJournal articlepeer-review

  23. Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease

    Leung, C., Herath, C. B., Jia, Z., Andrikopoulos, S., Brown, B. E., Davies, Michael J., Rivera, L. R., Furness, J. B., Forbes, J. M. & Angus, P. W., 21 Sep 2016, In: World Journal of Gastroenterology. 22, 35, p. 8026-8040 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins

    Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael J. & Lund, Marianne N., 2016, In: Free Radical Biology & Medicine. 97, p. 148-157 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael J. & Dean, R. T., Sep 2001, In: Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael J., Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Nitration alters laminin polymerization: [Meeting Abstract]

    Lorentzen, Lasse Gøbel & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.

    Research output: Contribution to journalConference abstract in journalpeer-review

  30. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Proteomic analysis of the extracellular matrix of human atherosclerotic plaques shows marked changes between plaque types

    Lorentzen, Lasse Gøbel, Yeung, K., Eldrup, Nikolaj, Eiberg, Jonas Peter, Sillesen, Henrik & Davies, Michael J., 2024, In: Matrix Biology Plus. 21, 14 p., 100141.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Proteomic Characterization of Atherosclerotic Lesions in Situ Using Percutaneous Coronary Intervention Angioplasty Balloons-Brief Report

    Lorentzen, Lasse Gøbel, Hansen, G. M., Iversen, Kasper, Bundgård, Henning & Davies, Michael J., 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 7, p. 857-864

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

    Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: Free Radical Biology & Medicine. 94, p. 88-98 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael J., Jul 2000, In: Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael J., 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael J., 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Azocompounds as generators of defined radical species: Contributions and challenges for free radical research

    López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 160, p. 78-91

    Research output: Contribution to journalReviewpeer-review

  39. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael J., Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In: International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Chasing Great Paths of Helmut “Oxidative Stress” Sies

    Majima, H., Indo, H., Nakanishi, I., Suenaga, S., Matsumoto, K., Matsui, H., Minamiyami, Y., Ichikawa, H., Yen, H., Hawkins, C., Davies, Michael J., Ozawa, T. & St. Clair, D., 2016, In: Archives of Biochemistry and Biophysics. 595, p. 54-60 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael J., Apr 2006, In: B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

    Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 2018, In: Journal of Proteome Research. 17, 6, p. 2017-2027

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

    Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Journal of Biological Chemistry. 296, 100360.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Absence of synproportionation between oxy and ferryl leghemoglobin. off

    Mathieu, C., Swaraj, K., Davies, Michael J., Trinchant, J. C. & Puppo, A., Aug 1997, In: Free Radical Research. 27, 2, p. 165-71 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael J., 1998, In: Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael J., Beattie, J. H. & Galley, H. F., 2015, In: British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael J., 15 Mar 2008, In: Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael J., Jun 2010, In: B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael J., 2011, In: Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journalJournal articlepeer-review

  50. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis

    Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael J., Jul 2012, In: Atherosclerosis. 223, 1, p. 144-51 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael J. & Puppo, A., 16 Aug 1995, In: Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael J., Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In: The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael J., 27 Mar 2015, In: Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael J., Aug 2013, In: Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael J., Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael J., 15 Jan 2012, In: Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael J., 2014, In: PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journalJournal articlepeer-review

  63. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael J., Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  64. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael J. & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael J., Dean, R. T. & Fu, S., Nov 1998, In: Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael J. & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls

    Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael J., 2022, In: Redox Biology. 52, 8 p., 102299.

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

    Murphy, M. P., Bayir, H., Belousov, V., Chang, C. J., Davies, K. J. A., Davies, M. J., Dick, T. P., Finkel, T., Forman, H. J., Janssen-Heininger, Y., Gems, D., Kagan, V. E., Kalyanaraman, B., Larsson, N. G., Milne, G. L., Nyström, T., Poulsen, H. E., Radi, R., Van Remmen, H., Schumacker, P. T. & 5 others, Thornalley, P. J., Toyokuni, S., Winterbourn, C. C., Yin, H. & Halliwell, B., 2022, In: Nature Metabolism. 4, 6, p. 651-662

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael J., Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael J., Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress

    Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael J., Schiesser, C. H. & Parry, L. J., Mar 2017, In: Biochemical Pharmacology. 128, p. 34-45 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael J., Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I

    Nobecourt, E., Zeng, J., Davies, Michael J., Brown, B. E., Yadav, S., Barter, P. J. & Rye, K. -., Jun 2008, In: Diabetologia. 51, 6, p. 1008-1017 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase

    Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  76. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael J., Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2019, In: Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry: [Meeting Abstract]

    Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S56-S57 P-40.

    Research output: Contribution to journalConference abstract in journalpeer-review

  79. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., Oct 2018, In: Redox Biology. 19, p. 388-400

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journalConference abstract in journalpeer-review

  81. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 20, p. 496-513

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing

    Park, J. I., Grant, C. M., Davies, Michael J. & Dawes, I. W., 4 Sep 1998, In: The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals

    Park, J. S., Wood, P. M., Davies, Michael J., Gilbert, B. C. & Whitwood, A. C., Nov 1997, In: Free Radical Research. 27, 5, p. 447-58 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  85. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  86. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., Aug 2007, In: Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies

    Pattison, D. I., Levina, A., Davies, Michael J. & Lay, P. A., 15 Jan 2001, In: Inorganic Chemistry. 40, 2, p. 214-7 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael J., Levina, A., Dixon, N. E. & Lay, P. A., 2001, In: Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

    Pattison, D. I. & Davies, Michael J., 2001, In: Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 130-2 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 26 Jun 2000, In: Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  92. Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases

    Pattison, David & Davies, Michael J., 2006, In: Current Medicinal Chemistry. 13, 27, p. 3271-3290 20 p.

    Research output: Contribution to journalReviewpeer-review

  93. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  94. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies

    Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael J., 1 Nov 2012, In: Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  96. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael J., 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  98. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journalJournal article

  99. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael J., 1 Aug 2002, In: Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 38036205