Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2020
  2. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase. / Gamon, Luke F.; Dieterich, Simon; Ignasiak, Marta T.; Schrameyer, Verena; Davies, Michael J.

    In: Redox Biology, Vol. 28, 101331, 2020.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. E-pub ahead of print

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-d-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings. / Zacharias, Triantafyllos; Flouda, Konstantina; Jepps, Thomas A; Gammelgaard, Bente; Schiesser, Carl H; Davies, Michael J.

    In: Biochemical Pharmacology, 05.09.2019, p. 113631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins : [Meeting Abstract]. / Gamon, Luke F.; Ignasiak, Marta T.; Dieterich, Simon D.; Sauerland, Max B.; Goll, Sandra T.; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 2, 01.08.2019, p. S8-S8.

    Research output: Contribution to journalConference articleResearch

  6. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway : [Meeting Abstract]. / Shu, Nan; Hagglund, Per Marten; Davies, Michael.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 8, 01.08.2019, p. S9-S9.

    Research output: Contribution to journalConference articleResearch

  7. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function : [Meeting Abstract]. / Shu, Nan; Davies, Michael.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 168, 01.08.2019, p. S49-S49.

    Research output: Contribution to journalConference articleResearch

  8. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) : a remarkable selenium-containing therapeutic molecule. / Davies, Michael J.; Schiesser, Carl H.

    In: New Journal of Chemistry, Vol. 43, No. 25, 2019, p. 9759-9765.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism. / Avila, Felipe; Ravello, Natalia; Zanocco, Antonio L.; Gamon, Luke F.; Davies, Michael J.; Silva, Eduardo.

    In: Free Radical Biology and Medicine, Vol. 141, 2019, p. 103-114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization : [Meeting Abstract]. / Gamon, Luke F.; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 70, 2019, p. S25-S25.

    Research output: Contribution to journalConference articleResearch

  11. Published

    Analysis of protein chlorination by mass spectrometry. / Nybo, Tina; Davies, Michael J.; Rogowska-Wrzesinska, Adelina.

    In: Redox Biology, Vol. 26, UNSP 101236, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan. / Fuentes-Lemus, Eduardo; Mariotti, Michele; Hagglund, Per; Leinisch, Fabian; Fierro, Angelica; Silva, Eduardo; Lopez-Alarcon, Camilo; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 143, 2019, p. 375-386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula. / Chen, Zhifei; Leinisch, Fabian; Greco, Ines; Zhang, Wei; Shu, Nan; Chuang, Christine Y.; Lund, Marianne N.; Davies, Michael J.

    In: Free Radical Research, Vol. 53, No. 1, 2019, p. 68-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase. / Nybo, Tina; Dieterich, Simon; Gamon, Luke F.; Chuang, Christine Y.; Hammer, Astrid; Hoefler, Gerald; Malle, Ernst; Rogowska-Wrzesinska, Adelina; Davies, Michael J.

    In: Redox Biology, Vol. 20, 2019, p. 496-513.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase : Implications for enzymatic activity and antioxidant action. / Tiwari, Manish Kumar; Hägglund, Per Mårten; Møller, Ian Max; Davies, Michael Jonathan; Bjerrum, Morten Jannik.

    In: Redox Biology, Vol. 26, 101262, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models. / Chen, Zhifei; Kondrashina, Alina; Greco, Ines; Gamon, Luke F.; Lund, Marianne N.; Giblin, Linda; Davies, Michael J.

    In: Journal of Agricultural and Food Chemistry, Vol. 67, No. 19, 2019, p. 5634-5646.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}. / Juhl, Pernille; Bomdesen, Sandie; Bay-Jensen, Anne-Christine; Karsdal, Morten; Davies, Michael Jonathan; Siebuhr, Anne Sofie.

    In: Annals of the Rheumatic Diseases, Vol. 78, No. S2, THU0335, 2019, p. 448-449.

    Research output: Contribution to journalConference articleResearch

  18. Published

    Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells. / Cai, Huan; Chuang, Christine Y.; Vanichkitrungruang, Siriluck; Hawkins, Clare L.; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 134, 2019, p. 526-536.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications. / Lorentzen, Lasse G.; Chuang, Christine Y.; Rogowska-Wrzesinska, Adelina; Davies, Michael J.

    In: Redox Biology, Vol. 24, UNSP 101226, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]. / Flouda, Konstantina; Davies, Michael; Hawkins, Clare.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 64, 2019, p. S23-S24.

    Research output: Contribution to journalConference articleResearch

  21. Published

    Iodide anions show protective and damaging effects in oxidation of amino acids, peptides and proteins : [Meeting Abstract]. / Ignasiak-Kciuk, Marta; Shashikadze, Bachuki; Frackowiak, Kamil; Gamon, Luke F.; Davies, Michael J.; Marciniak, Bronislaw.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 89, 2019, p. S30-S30.

    Research output: Contribution to journalConference articleResearchpeer-review

  22. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function. / Vanichkitrungruang, Siriluck; Chuang, Christine Y.; Hawkins, Clare L.; Hammer, Astrid; Hoefler, Gerald; Malle, Ernst; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 136, 2019, p. 118-134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]. / Escobar, E.; Fuentes-Lemus, E.; Figueroa, J. D.; Fuentealba, D.; Denicola, A.; Alvarez, B.; Leinisch, F.; Davies, M. J.; Lopez-Alarcon, C.

    In: Free Radical Biology and Medicine, Vol. 139, No. S1, 53, 2019, p. S21-S21.

    Research output: Contribution to journalConference articleResearch

  24. E-pub ahead of print

    Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112). / Tur, Josep A.; Jacob, Claus; Chaimbault, Patrick; Tadayyon, Mohammad; Richling, Elke; Hermans, Nina; dos Santos, Claudia Nunes; Diederich, Marc; Giblin, Linda; Elhabiri, Mourad; Gaucher, Caroline; Andreoletti, Pierre; Fernandes, Ana; Davies, Michael; Bartoszek, Agnieszka; Cherkaoui-Malki, Mustapha.

    In: Free Radical Research, 2019.

    Research output: Contribution to journalEditorialResearchpeer-review

  25. Published

    Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching. / David Figueroa, Juan; Fuentes-Lemus, Eduardo; Dorta, Eva; Melin, Victoria; Cortes-Rios, Javiera; Faundez, Mario; Contreras, David; Denicola, Ana; Alvarez, Beatriz; Davies, Michael J.; Lopez-Alarcon, Camilo.

    In: Redox Biology, Vol. 24, UNSP 101207, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications. / Shu, Nan; Lorentzen, Lasse G.; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 137, 2019, p. 169-180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode. / Silva, Eduardo; Barrias, Pablo; Fuentes-Lemus, Eduardo; Tirapegui, Cristian; Aspee, Alexis; Carroll, Luke; Davies, Michael J.; Lopez-Alarcon, Camilo.

    In: Free Radical Biology and Medicine, Vol. 131, 2019, p. 133-143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Tempus fugit horizontal ellipsis. / Davies, Michael.

    In: Free Radical Research, Vol. 53, No. 1, 2019, p. 1-1.

    Research output: Contribution to journalEditorialResearchpeer-review

  29. E-pub ahead of print

    Whey proteins: targets of oxidation, or mediators of redox protection. / Giblin, Linda; Yalcin, A. Suha; Bicim, Gokhan; Kramer, Anna C.; Chen, Zhifei; Callanan, Michael J.; Arranz, Elena; Davies, Michael J.

    In: Free Radical Research, 2019.

    Research output: Contribution to journalReviewResearchpeer-review

  30. 2018
  31. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function. / Nybo, Tina; Cai, Huan; Chuang, Christine Y.; Gamon, Luke F.; Rogowska-Wrzesinska, Adelina; Davies, Michael J.

    In: Redox Biology, Vol. 19, 10.2018, p. 388-400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals. / Leinisch, Fabian; Mariotti, Michele; Hagglund, Per; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 126, 10.2018, p. 73-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation. / Fuentes-Lemus, Eduardo; Silva, Eduardo; Barrias, Pablo; Aspee, Alexis; Escobar, Elizabeth; Lorentzen, Lasse G.; Carroll, Luke; Leinisch, Fabian; Davies, Michael J.; Lopez-Alarcon, Camilo.

    In: Free Radical Biology and Medicine, Vol. 124, 20.08.2018, p. 176-188.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent. / Fuentes-Lemus, E.; Silva, E.; Leinisch, F.; Dorta, E.; Lorentzen, L. G.; Davies, M. J.; Lopez-Alarcon, C.

    In: Food Chemistry, Vol. 256, 01.08.2018, p. 119-128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice : [Meeting Abstract]. / Zacharias, Triantafyllos; Flouda, Konstantina; Jepps, Thomas; Christoffersen, Christina; Pedersen, Tanja; Gammelgaard, Bente; Schiesser, Carl; Davies, Michael.

    In: Free Radical Biology & Medicine, Vol. 120, No. S1, P-79, 20.05.2018, p. S68-S68.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  36. Published

    Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products. / Carroll, Luke; Pattison, David I.; Davies, Justin B.; Anderson, Robert F.; Lopez-Alarcon, Camilo; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 118, 04.2018, p. 126-136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives. / Borges, Elton L.; Ignasiak, Marta T.; Velichenko, Yuliia; Perin, Gelson; Hutton, Craig A.; Davies, Michael J.; Schiesser, Carl H.

    In: Chemical Communications, Vol. 54, No. 24, 25.03.2018, p. 2990-2993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function. / Degendorfer, Georg; Chuang, Christine Y; Mariotti, Michele; Hammer, Astrid; Hoefler, Gerald; Hägglund, Per; Malle, Ernst; Wise, Steven G; Davies, Michael J.

    In: Free Radical Biology & Medicine, Vol. 115, No. S1, 01.02.2018, p. 202-214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry : [Meeting Abstract]. / Nybo, Tina; Davies, Michael J.; Rogowska-Wrzesinska, Adelina.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-40, 2018, p. S56-S57.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment. / Polonchuk, Liudmila; Chabria, Mamta; Badi, Laura; Hoflack, Jean-Christophe; Davies, Michael J.; Figtree, Gemma; Gentile, Carmine.

    In: Journal of Pharmacological and Toxicological Methods, Vol. 93, 2018, p. 167.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula : [Meeting Abstract]. / Chen, Zhifei; Leinisch, Fabian; Greco, Ines; Zhang, Wei; Shu, Nan; Chuang, Christine Yu-Nung; Lund, Marianne Nissen; Davies, Michael Jonathan.

    In: Free Radical Biology and Medicine, Vol. 120, No. Supplement 1, P-8, 2018, p. S47.

    Research output: Contribution to journalConference abstract in journalResearch

  42. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function : [Meeting Abstract]. / Nybo, Tina; Cai, Huan; Chuang, Christine; Gamon, Luke; Rogowska-Wrzesinska, Adelina; Davies, Michael.

    In: Free Radical Biology & Medicine, Vol. 120, No. S1, P-41 , 2018, p. S24-S24.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein. / Tiwari, Manish Kumar; Leinisch, Fabian; Sahin, Cagla; Møller, Ian Max; Otzen, Daniel Erik; Davies, Michael Jonathan; Bjerrum, Morten Jannik.

    In: Free Radical Biology & Medicine, Vol. 121, 2018, p. 38-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin. / Nielsen, Line R.; Lund, Marianne N.; Davies, Michael J.; Nielsen, Jacob H.; Nielsen, Søren B.

    In: International Dairy Journal, Vol. 79, 2018, p. 52-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function : [Meeting Abstract]. / Degendorfer, Georg; Lorentzen, Lasse G.; Chuang, Christine Y.; Mariotti, Michele; Hammer, Astrid; Hoefler, Gerald; Haegglund, Per; Malle, Ernst; Wise, Steven; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-192 , 2018, p. S102-S103.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Identification and characterization of protein cross-links induced by oxidative reactions. / Hagglund, Per; Mariotti, Michele; Davies, Michael J.

    In: Expert Review of Proteomics, Vol. 15, No. 8, 2018, p. 665-681.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme : [Meeting Abstract]. / Silva, E.; Tirapegui, C.; Fuentes-Lemus, E.; Barrias, P.; Aspee, A.; Lorentzen, L. G.; Caroll, L.; Leinisch, F.; Davies, M. J.; Lopez-Alarcon, C.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-46, 2018, p. S58-S59.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Kinetics and biological consequences of quinone-induced protein adduction : [Meeting Abstract]. / Shu, Nan; Lorentzen, Lasse G.; Davies, Michael J.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-34, 2018, p. S55-S55.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. / Mariotti, Michele; Leinisch, Fabian; Leeming, Diana Julie; Svensson, Birte; Davies, Michael J.; Hagglund, Per.

    In: Journal of Proteome Research, Vol. 17, No. 6, 2018, p. 2017-2027.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Mechanistic view of iodide in oxidative stress : [Meeting Abstract]. / Kciuk, Marta Ignasiak; Davies, Michael Jonathan; Marciniak, Bronislaw.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-254, 2018, p. S122-S122.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  51. Published

    Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis : [Meeting Absract]. / Cai, H.; Chuang, C. Y.; Davies, M. J.

    In: International Journal of Experimental Pathology, Vol. 99, No. 6, 2018, p. A24-A24.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  52. Published

    Nitration alters laminin polymerization : [Meeting Abstract]. / Lorentzen, Lasse; Davies, Michael.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-271, 2018, p. S127-S127.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  53. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals : [Meeting Abstract]. / Fuentes-Lemus, Eduardo; Silva, Eduardo; Barrias, Pablo; Aspee, Alexis; Lorentzen, Lasse; Carroll, Luke; Leinisch, Fabian; Davies, Michael Jonathan; Lopez-Alarcon, Camilo.

    In: Free Radical Biology and Medicine, Vol. 120, No. S1, P-50 , 2018, p. S60-S60.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

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