Michael J. Davies

Michael J. Davies

Professor


  1. One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation

    Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael J., 21 Mar 2011, In: Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats

    Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Oxidant-induced glutathionylation at protein disulfide bonds

    Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael J., 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Oxidant-mediated modification and cross-linking of beta-2-microglobulin

    Jiang, S., Fuentes Lemus, Eduardo & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 187, p. 59-71

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells

    Clemen, R., Fuentes Lemus, Eduardo, Bekeschus, S. & Davies, Michael J., 2023, In: Redox Biology. 65, 14 p., 102835.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite

    Thomas, S. R., Davies, Michael J. & Stocker, R., 1998, In: Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Oxidation and modification of extracellular matrix and its role in disease

    Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

    Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael J., 1 Aug 2002, In: Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael J. & Lopez-Alarcon, C., 2016, In: RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks

    Fuentes Lemus, Eduardo, Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael J., 2008, In: Biochemical Journal. 410, 3, p. 565-574

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins

    Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael J., 2021, In: Redox Biology. 38, 16 p., 101822.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Oxidation of the active site cysteine residue of glyceraldehyde-3-phosphate dehydrogenase to the hyper-oxidized sulfonic acid form is favored under crowded conditions

    Glover, M. R., Davies, Michael J. & Fuentes Lemus, Eduardo, 2024, In: Free Radical Biology and Medicine. 212, p. 1-9 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journalReviewpeer-review

  19. Published

    Oxidative damage on proteins is enhanced in crowded environments

    Fuentes Lemus, Eduardo, Gamon, Luke Francis, Lopez-Alarcon, C. & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. S31-S32

    Research output: Contribution to journalConference abstract in journal

  20. Published

    Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?

    Hawkins, C. L. & Davies, Michael J., 27 Feb 1997, In: B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael J., 15 Jun 2008, In: Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes

    Popa, I., Touboul, D., Andersson, T., Fuentes Lemus, Eduardo, Santerre, C., Davies, Michael J. & Lood, R., 2023, In: Microorganisms. 11, 9, 15 p., 2260.

    Research output: Contribution to journalJournal articlepeer-review

  23. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael J., Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In: International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Peroxides and protein oxidation

    Davies, Michael J., 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  25. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

    Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, Per Mårten & Davies, Michael J., Nov 2017, In: Free Radical Biology & Medicine. 112, p. 240-252 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]

    Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.

    Research output: Contribution to journalConference abstract in journal

  27. Published

    Peroxyl radicals modify 6-phosphogluconolactonase from Escherichia coli via oxidation of specific amino acids and aggregation which inhibits enzyme activity

    Reyes, J. S., Fuentes Lemus, Eduardo, Romero, J., Arenas, F., Fierro, A., Davies, Michael J. & López-Alarcón, C., 2023, In: Free Radical Biology and Medicine. 204, p. 118-127

    Research output: Contribution to journalJournal articlepeer-review

  28. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

    Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael J., 15 Jul 2010, In: Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Peroxynitrous acid-modified extracellular matrix alters gene and protein expression in human coronary artery smooth muscle cells and induces a pro-inflammatory phenotype

    Jørgensen, S. M., Lorentzen, Lasse Gøbel, Chuang, Christine & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 186, p. 43-52

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)

    Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael J., Bartoszek, A. & Cherkaoui-Malki, M., 2019, In: Free Radical Research. 53, S1, p. 1163-1170

    Research output: Contribution to journalJournal articlepeer-review

  34. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael J., 2014, In: PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Phenotypic changes to vascular smooth muscle cells induced by extracellular matrix modification

    Jorgensen, S. M., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology & Medicine. 165, Suppl. 1, p. 36-37 NC38.

    Research output: Contribution to journalConference abstract in journalpeer-review

  36. Published

    Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix

    Jorgensen, S. M., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, 1 p., NC38.

    Research output: Contribution to journalConference abstract in journal

  37. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Mar 2003, In: Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Photo-oxidation of proteins

    Pattison, D. I., Rahmanto, A. S. & Davies, Michael J., Jan 2012, In: Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Photo-oxidation of proteins and its role in cataractogenesis

    Davies, Michael J. & Truscott, R. J., 2001, In: Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase

    Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael J., 15 Sep 2012, In: Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination

    Blossom, B. M., Russo, D. A., Singh, R. K., Van Oort, B., Keller, M. B., Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael J., Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In: ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues

    Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Mar 1998, In: Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives

    Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael J., 19 Nov 2012, In: Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Prevention of degradation of the natural high potency sweetener (2R,4R)-monatin in mock beverage solutions

    Storkey, C., Pattison, David, Koehler, J. A., Gaspard, D. S., Evans, J. C., Hagestuen, E. D. & Davies, Michael J., 2015, In: Food Chemistry. 173, p. 645-651

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Processed foods drive intestinal barrier permeability and microvascular diseases

    Snelson, M., Tan, S. M., Clarke, R. E., De Pasquale, C., Thallas-Bonke, V., Nguyen, T. V., Penfold, S. A., Harcourt, B. E., Sourris, K. C., Lindblom, R. S., Ziemann, M., Steer, D., El-Osta, A., Davies, M. J., Donnellan, L., Deo, P., Kellow, N. J., Cooper, M. E., Woodruff, T. M., Mackay, C. R. & 2 others, Forbes, J. M. & Coughlan, M. T., 2021, In: Science Advances. 7, 14, eabe4841.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael J., Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage

    Davies, Michael J., 1 Dec 1996, In: Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification

    Forman, H. J., Davies, Michael J., Krämer, A. C., Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In: Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 38036205