Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N, 12.6, Building: 30
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beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In : Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent
Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael Jonathan & Lopez-Alarcon, C., 1 Aug 2018, In : Food Chemistry. 256, p. 119-128Research output: Contribution to journal › Journal article › Research › peer-review
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Xanthine oxidase activity and free radical generation in patients with sepsis syndrome
Galley, H. F., Davies, Michael Jonathan & Webster, N. R., 1996, In : Critical Care Medicine. 24, 10, p. 1649-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Krämer, Anna Carola, Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › Research › peer-review
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael Jonathan, 1 Jul 2008, In : Patient Education and Counseling. 72, 1, p. 88-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications
Rykær, M., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 3 Nov 2017, In : Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation
Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In : Free Radical Biology and Medicine. 153, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
Leinisch, F., Mariotti, M., Andersen, Sofie Hagel, Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In : Scientific Reports. 10, 1, 11 p., 3106.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage
Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In : Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase
Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael Jonathan, 27 Mar 2015, In : Free Radical Research. 49, 6, p. 743-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study
Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 5 Aug 2008, In : Biochemistry. 47, 31, p. 8237-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage
Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael Jonathan, Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In : Scientific Reports. 7, 10 p., 46282.Research output: Contribution to journal › Journal article › Research › peer-review
The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction
Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael Jonathan, 1 Jan 2014, In : Biochemical Journal. 457, 1, p. 89-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael Jonathan, Iozzo, R. V. & Whitelock, J. M., Apr 2014, In : Matrix Biology. 35, p. 112-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The retina: oxidative stress and diabetes
van Reyk, D. M., Gillies, M. C. & Davies, Michael Jonathan, 2003, In : Redox Report (Online). 8, 4, p. 187-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage
Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In : Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael Jonathan, 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 896-905 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael Jonathan, Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In : PLoS ONE. 4, 11, e7755.Research output: Contribution to journal › Journal article › Research › peer-review
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The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael Jonathan & López-Alarcón, C., Nov 2017, In : Free Radical Biology and Medicine. 112, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice
Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael Jonathan, May 2015, In : Atherosclerosis. 240, 1, p. 234-241 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies
Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael Jonathan, 1 Nov 2012, In : Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael Jonathan, 1 Jan 2016, In : Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In : Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael Jonathan, Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In : Inflammopharmacology. 21, 3, p. 201-32 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes
Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In : Archives of Biochemistry and Biophysics. 689, 7 p., 108443.Research output: Contribution to journal › Journal article › Research › peer-review
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The immunoproteasome is induced by cytokines and regulates apoptosis in human islets
Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael Jonathan, Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In : Journal of Endocrinology. 233, 3, p. 369-379 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing
Park, J. I., Grant, C. M., Davies, Michael Jonathan & Dawes, I. W., 4 Sep 1998, In : The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael Jonathan & Khunti, K., 1 Feb 2010, In : Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.Research output: Contribution to journal › Review › Research › peer-review
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The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael Jonathan, Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, Balaji & Khunti, K., 1 Jul 2011, In : Diabetic Medicine. 28, 7, p. 785-788 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › Research › peer-review
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The DESMOND educational intervention
Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Tempus fugit horizontal ellipsis
Davies, Michael Jonathan, 2019, In : Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › Research › peer-review
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Temperature Activated Diffusion of Radicals through Ion Implanted Polymers
Wakelin, E. A., Davies, Michael Jonathan, Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In : A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content
Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael Jonathan, Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In : Nephrology. 18, 1, p. 47-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael Jonathan & Schiesser, C. H., 25 Mar 2018, In : Chemical Communications. 54, 24, p. 2990-2993Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis and antioxidant capacity of 5-selenopyranose derivatives
Storkey, C., Davies, Michael Jonathan, White, J. M. & Schiesser, C. H., 14 Sep 2011, In : Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael Jonathan & van Reyk, D. M., Feb 2014, In : Atherosclerosis. 232, 2, p. 403-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Apr 2018, In : Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › Research › peer-review
Superoxide radicals have a protective role during H2O2 stress
Thorpe, G. W., Reodica, M., Davies, Michael Jonathan, Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In : Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sulfur and selenium in oxidation protection
Davies, Michael Jonathan, 2015, In : La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54Research output: Contribution to journal › Review › Research › peer-review
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Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals
Leinisch, F., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, Oct 2018, In : Free Radical Biology and Medicine. 126, p. 73-86Research output: Contribution to journal › Journal article › Research › peer-review
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Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Special issue for the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017)
Khramtsov, V. V. & Davies, Michael Jonathan, 2018, In : Free Radical Research. 52, 3, p. 305-306Research output: Contribution to journal › Editorial › Research
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Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)
Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael Jonathan, 2 Oct 2016, In : Free Radical Research. 50, 10, p. 1045-1046Research output: Contribution to journal › Editorial › Research
Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction
Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael Jonathan & Witting, P. K., 1 Jan 2010, In : Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides
Wright, A., Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 159-61 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues
Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael Jonathan, 6 Jun 2003, In : Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis
Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins
Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael Jonathan, Dec 2017, In : Free Radical Biology & Medicine. 113, p. 395-405 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids as direct and indirect antioxidants
Rahmanto, A. S. & Davies, Michael Jonathan, Nov 2012, In : I U B M B Life. 64, 11, p. 863-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage
Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael Jonathan, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 305-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study
Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In : Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study
Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In : Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, Chaorui, Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In : Redox Biology. 36, 14 p., 101666.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In : P L o S One. 11, 12, 16 p., e0168844.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function
Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael Jonathan, St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).Research output: Chapter in Book/Report/Conference proceeding › Book chapter
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Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode
Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 131, p. 133-143Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses
Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides
Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 241-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3
Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1
Kovacevic, Z., Sahni, S., Lok, K. H., Davies, Michael Jonathan, Wink, D. A. & Richardson, D. R., May 2017, In : B B A - Reviews on Cancer. 1861, 5 Pt A, p. 995-999 5 p.Research output: Contribution to journal › Review › Research › peer-review
Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach
Storkey, C., Davies, Michael Jonathan & Pattison, D. I., Aug 2014, In : Free Radical Biology & Medicine. 73, p. 60-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus
Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael Jonathan, Jun 2012, In : Atherosclerosis. 222, 2, p. 512-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability
Karimi, M., Ignasiak, M. T., Chan, B., Croft, A. K., Radom, L., Schiesser, C. H., Pattison, D. I. & Davies, Michael Jonathan, 12 Dec 2016, In : Scientific Reports. 6, 12 p., 38572.Research output: Contribution to journal › Journal article › Research › peer-review
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Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael Jonathan, Jan 2004, In : Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications
Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 137, p. 169-180Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael Jonathan & Pattison, D. I., 2015, In : Free Radical Research. 49, 6, p. 750-767 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species
Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reaction between protein radicals and other biomolecules
Østdal, H., Davies, Michael Jonathan & Andersen, H. J., 15 Jul 2002, In : Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA
Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In : Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quinone-induced protein modifications: kinetic preference for reaction of 1,2-benzoquinones with thiol groups in proteins
Li, Y., Jongberg, S., Andersen, Mogens Larsen, Davies, Michael Jonathan & Lund, Marianne N., 2016, In : Free Radical Biology & Medicine. 97, p. 148-157 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline
Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In : Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › Research › peer-review
Protein-bound kynurenine is a photosensitizer of oxidative damage
Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In : Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass
Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein oxidation and peroxidation
Davies, Michael Jonathan, 2016, In : Biochemical Journal. 473, 7, p. 805-825 21 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Protein oxidation and ageing
Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin
Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Feb 1998, In : Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Forman, H. J., Davies, Michael Jonathan, Krämer, Anna Carola, Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In : Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage
Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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