Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2006
  2. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In : Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In : Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2007
  6. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael Jonathan, 15 Jan 2007, In : Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

    Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In : F E B S Journal. 274, 6, p. 1530-41 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro

    Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, 6 Mar 2007, In : FEBS letters. 581, 5, p. 1067-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products

    Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In : Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin

    Davies, Michael Jonathan, Thaware, P. K., Tringham, J. R., Howe, J., Jarvis, J., Johnston, V., Kitchener, D. L., Skinner, Timothy, McNally, P. G. & Lawrence, I. G., 1 Jul 2007, In : Diabetic Medicine. 24, 7, p. 714-719 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, Dec 2007, In : Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2008
  18. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The DESMOND educational intervention

    Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation

    Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael Jonathan, May 2008, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jun 2008, In : Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study

    Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael Jonathan, 1 Jul 2008, In : Patient Education and Counseling. 72, 1, p. 88-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 5 Aug 2008, In : Biochemistry. 47, 31, p. 8237-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2008, In : Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    'Educator talk' and patient change: Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Sep 2008, In : Diabetic Medicine. 25, 9, p. 1117-1120 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid

    Kennett, E. C. & Davies, Michael Jonathan, 1 Sep 2008, In : Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In : Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael Jonathan & Witting, P. K., 15 Sep 2008, In : Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals

    Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael Jonathan, Nov 2008, In : Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial

    Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael Jonathan, 1 Dec 2008, In : Diabetic Medicine. 25, 12, p. 1454-1461 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2009
  37. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In : Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Hypobromous acid and bromamine production by neutrophils and modulation by superoxide

    Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael Jonathan, 1 Feb 2009, In : Biochemical Journal. 417, 3, p. 773-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

    Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael Jonathan, 1 Jul 2009, In : Biochemical Journal. 421, 1, p. 79-86 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In : Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 15 Aug 2009, In : Biochemical Journal. 422, 1, p. 111-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus

    Aujla, N., Abrams, K. R., Davies, Michael Jonathan, Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In : PLoS ONE. 4, 11, e7755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2010
  47. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy

    Sourris, K. C., Harcourt, B. E., Penfold, S. A., Yap, F. Y. T., Morley, A. L., Morgan, P. E., Davies, Michael Jonathan, Baker, S. T., Jerums, G. & Forbes, J. M., 2010, In : Journal of Diabetes Research. 2010, p. 974681

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael Jonathan, Jan 2010, In : Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction

    Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael Jonathan & Witting, P. K., 1 Jan 2010, In : Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review

    Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael Jonathan & Khunti, K., 1 Feb 2010, In : Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael Jonathan, Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

    Khunti, K., Taub, N., Tringham, J., Jarvis, J., Farooqi, A., Skinner, Timothy & Davies, Michael Jonathan, 1 Apr 2010, In : Primary Care Diabetes. 4, 1, p. 25-32 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations

    Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 15 Apr 2010, In : Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Apr 2010, In : Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

    Moheimani, F., Morgan, P. E., van Reyk, D. M. & Davies, Michael Jonathan, Jun 2010, In : B B A - Reviews on Cancer. 1802, 6, p. 561-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

    Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jul 2010, In : Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 965-967 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools

    Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael Jonathan, 1 Aug 2010, In : Diabetic Medicine. 27, 8, p. 896-905 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In : Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis

    Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael Jonathan, 26 Aug 2010, In : BMJ (Online). 341, 7770, c4093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael Jonathan, 30 Nov 2010, In : Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3

    Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, Michael Jonathan & Winterbourn, C. C., 1 Dec 2010, In : Biochemical Journal. 432, 2, p. 313-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study

    Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In : Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2011
  65. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins

    Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael Jonathan, 2011, In : Journal of Diabetes Research. 2011, p. 851280

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

    Davies, Michael Jonathan, Jan 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

    Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Jan 2011, In : Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In : Psychology and Health. 26, 3, p. 321-335 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation

    Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael Jonathan, 21 Mar 2011, In : Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The association between anxiety and measures of glycaemia in a population-based diabetes screening programme

    Aujla, N., Davies, Michael Jonathan, Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, Balaji & Khunti, K., 1 Jul 2011, In : Diabetic Medicine. 28, 7, p. 785-788 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation

    Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael Jonathan, 27 Jul 2011, In : Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan, Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In : International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study

    Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael Jonathan, 1 Sep 2011, In : Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Synthesis and antioxidant capacity of 5-selenopyranose derivatives

    Storkey, C., Davies, Michael Jonathan, White, J. M. & Schiesser, C. H., 14 Sep 2011, In : Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Mechanisms and consequences of oxidative damage to extracellular matrix

    Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael Jonathan, Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In : Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides

    Suryo Rahmanto, A. & Davies, Michael Jonathan, 15 Dec 2011, In : Free Radical Biology & Medicine. 51, 12, p. 2288-99 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. 2012
  79. Free Radical Research origins

    Davies, Michael Jonathan, Jan 2012, In : Free Radical Research. 46, 1, p. 1

    Research output: Contribution to journalJournal articleResearch

  80. Photo-oxidation of proteins

    Pattison, D. I., Rahmanto, A. S. & Davies, Michael Jonathan, Jan 2012, In : Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

    Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael Jonathan, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 305-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael Jonathan, 15 Jan 2012, In : Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells

    Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael Jonathan, 1 Mar 2012, In : Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

    Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Mar 2012, In : Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?

    Truscott, R. J. W., Mizdrak, J., Friedrich, M. G., Hooi, M. Y., Lyons, B., Jamie, J. F., Davies, Michael Jonathan, Wilmarth, P. A. & David, L. L., Jun 2012, In : Experimental Eye Research. 99, p. 48-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus

    Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael Jonathan, Jun 2012, In : Atherosclerosis. 222, 2, p. 512-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In : BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis

    Moheimani, F., Kim, C. H. J., Rahmanto, A. S., van Reyk, D. M. & Davies, Michael Jonathan, Jul 2012, In : Atherosclerosis. 223, 1, p. 144-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine

    Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael Jonathan, 1 Jul 2012, In : Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael Jonathan & Hawkins, Clare Louise, Aug 2012, In : Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase

    Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael Jonathan, 15 Sep 2012, In : Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Selenium-containing amino acids as direct and indirect antioxidants

    Rahmanto, A. S. & Davies, Michael Jonathan, Nov 2012, In : I U B M B Life. 64, 11, p. 863-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies

    Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael Jonathan, 1 Nov 2012, In : Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives

    Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael Jonathan, 19 Nov 2012, In : Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Computational design of effective, bioinspired HOCl antioxidants: the role of intramolecular Cl+ and H+ shifts

    Karton, A., O'Reilly, R. J., Pattison, D. I., Davies, Michael Jonathan & Radom, L., 21 Nov 2012, In : Journal of the American Chemical Society. 134, 46, p. 19240-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins

    Cook, N. L., Pattison, D. I. & Davies, Michael Jonathan, 1 Dec 2012, In : Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. 2013
  98. Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages

    Brown, B. E., Nobecourt, E., Zeng, J., Jenkins, A. J., Rye, K. & Davies, Michael Jonathan, 2013, In : PLOS ONE. 8, 5, p. e65430

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content

    Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael Jonathan, Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In : Nephrology. 18, 1, p. 47-56 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)

    Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 531-42 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues

    Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael Jonathan & Silva, E., 18 Jan 2013, In : Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

    Graham, G. G., Davies, Michael Jonathan, Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In : Inflammopharmacology. 21, 3, p. 201-32 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine

    Kadiiska, M. B., Basu, S., Brot, N., Cooper, C., Saari Csallany, A., Davies, Michael Jonathan, George, M. M., Murray, D. M., Jackson Roberts, L., Shigenaga, M. K., Sohal, R. S., Stocker, R., Van Thiel, D. H., Wiswedel, I., Hatch, G. E. & Mason, R. P., Aug 2013, In : Free Radical Biology & Medicine. 61, p. 408-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael Jonathan, Aug 2013, In : Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Superoxide radicals have a protective role during H2O2 stress

    Thorpe, G. W., Reodica, M., Davies, Michael Jonathan, Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In : Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

    Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael Jonathan & Hawkins, Clare Louise, Dec 2013, In : Free Radical Biology & Medicine. 65, p. 1352-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. 2014
  108. Published

    Competitive reduction of perferrylmyoglobin radicals by protein thiols and plant phenols

    Jongberg, S., Lund, Marianne N., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2014, In : Journal of Agricultural and Food Chemistry. 62, 46, p. 11279-11288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

    Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205