Michael J. Davies

Michael J. Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    The structure of model and peptide disulfides markedly affects their reactivity and products formed with singlet oxygen

    Gao, Qing, Grzyb, K., Gamon, Luke Francis, Ogilby, P. R., Pędziński, T. & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 207, p. 320-329

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

    Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael J., 2020, In: Redox Biology. 28, 12 p., 101331.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

    Gamon, Luke Francis, Guo, C., He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael J., Sep 2020, In: Redox Biology. 36, 9 p., 101586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]

    Gamon, Luke Francis & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]

    Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.

    Research output: Contribution to journal › Conference abstract in journal › Research

  6. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

    Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael J., Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Xanthine oxidase activity and free radical generation in patients with sepsis syndrome

    Galley, H. F., Davies, Michael J. & Webster, N. R., 1996, In: Critical Care Medicine. 24, 10, p. 1649-53 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses

    Gad, N. A., Mizdrak, J., Pattison, D. I., Davies, Michael J., Truscott, R. J. W. & Jamie, J. F., Feb 2014, In: Investigative Ophthalmology & Visual Science. 55, 2, p. 849-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Oxidative damage on proteins is enhanced in crowded environments

    Fuentes Lemus, Eduardo, Gamon, Luke Francis, Lopez-Alarcon, C. & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. S31-S32

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks

    Fuentes Lemus, Eduardo, Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  14. Published

    Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways

    Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael J., 2021, In: Redox Biology. 48, 15 p., 102202.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification

    Fuentes Lemus, Eduardo, Reyes, J. S., López-Alarcón, C. & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 193, p. 551-566 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges

    Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

    Fuentes Lemus, Eduardo, Reyes, J. S., Figueroa, J. D., Davies, Michael J. & López-Alarcón, C., 2023, In: Biochemical Society Transactions. 51, 6, p. 2173–2187

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Tryptophan and Cysteine residues mediate chain reactions and propagation of oxidative damage in concentrated casein solutions

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 562 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  21. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan

    Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 143, p. 375-386

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 20 Aug 2018, In: Free Radical Biology and Medicine. 124, p. 176-188

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent

    Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael J. & Lopez-Alarcon, C., 1 Aug 2018, In: Food Chemistry. 256, p. 119-128

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael J. & Lopez-Alarcon, C., 2016, In: RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification

    Forman, H. J., Davies, Michael J., Krämer, A. C., Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In: Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Complexation of AAPH (2,2′-azobis(2-methylpropionamidine) dihydrochloride) with cucurbit[7]uril enhances the yield of AAPH-derived radicals

    Forero-Girón, A. C., Fuentealba, D., Mariño-Ocampo, N., Gutiérrez-Oliva, S., Herrera, B., Toro-Labbé, A., Fuentes Lemus, Eduardo, Davies, Michael J., Aliaga, M. E. & López-Alarcón, C., 2023, In: Journal of Molecular Liquids. 389, 9 p., 122840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]

    Flouda, K., Davies, Michael J. & Hawkins, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.

    Research output: Contribution to journal › Conference abstract in journal › Research

  29. Published

    Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

    Flouda, K., Gammelgaard, Bente, Davies, Michael J. & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage

    Flouda, K., Mercer, J., Davies, Michael J. & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Role of amino acid oxidation and protein unfolding in peroxyl radical and peroxynitrite-induced inactivation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides

    Figueroa, J. D., Fuentes Lemus, Eduardo, Reyes, J. S., Loaiza, M., Aliaga, M. E., Fierro, A., Leinisch, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Free Radical Biology and Medicine. 190, p. 292-306

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael J. & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function

    Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael J. & López-Alarcón, C., Nov 2017, In: Free Radical Biology and Medicine. 112, p. 60-68 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]

    Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis

    Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael J., Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In: Diabetes. 63, 2, p. 675-87 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers

    Doblas, L., Hägglund, Per Mårten, Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Archives of Biochemistry and Biophysics. 733, 7 p., 109482.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]

    Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

    Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Biochemistry and pathology of radical-mediated protein oxidation

    Dean, R. T., Fu, S., Stocker, R. & Davies, Michael J., 1997, In: Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Stable markers of oxidant damage to proteins and their application in the study of human disease

    Davies, Michael J., Fu, S., Wang, H. & Dean, R. T., Dec 1999, In: Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods

    Davies, Michael J., 2016, In: Methods. 109, p. 21-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. The oxidative environment and protein damage

    Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    EPR spin trapping of protein radicals

    Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael J., Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates

    Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael J., 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Free Radical Research origins

    Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1

    Research output: Contribution to journal › Journal article › Research

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