Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]
Gamon, Luke Francis & Davies, Michael Jonathan, 2019, In: Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.Research output: Contribution to journal › Conference abstract in journal › Research
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Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]
Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael Jonathan, 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.Research output: Contribution to journal › Conference abstract in journal › Research
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Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction
Gentile, C., Kesteven, S., Wu, J., Davies, Michael Jonathan, Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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A Novel Method for Isolating and Culturing Human Cardiomyocytes from Cryopreserved Tissues
Gentile, C., Kuehn, B., Davies, Michael Jonathan & dos Remedios, C. G., 2014, In: Biophysical Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Kramer, A. C., Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael Jonathan, 2019, In: Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael Jonathan, 26 Aug 2010, In: BMJ (Online). 341, 7770, c4093.Research output: Contribution to journal › Journal article › Research › peer-review
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Jan 2011, In: Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In: Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael Jonathan, Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In: Inflammopharmacology. 21, 3, p. 201-32 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study
Gray, L. J., Tringham, J. R., Davies, Michael Jonathan, Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In: Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
Guo, C., Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants. 9, 12, 14 p., 1255.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, C., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Jan 2013, In: Biochemical Journal. 449, 2, p. 531-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In: Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and characterization of protein cross-links induced by oxidative reactions
Hägglund, Per Mårten, Mariotti, M. & Davies, Michael Jonathan, 2018, In: Expert Review of Proteomics. 15, 8, p. 665-681Research output: Contribution to journal › Review › Research › peer-review
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Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats
Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Scientific Reports. 11, 1, 18 p., 12712.Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma
Havelund, J. F., Wojdyla, K. I., Davies, Michael Jonathan, Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In: Journal of Proteomics. 156, p. 40-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael Jonathan, 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?
Hawkins, C. L. & Davies, Michael Jonathan, 27 Feb 1997, In: B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, Benjamin James & Davies, Michael Jonathan, 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708Research output: Contribution to journal › Review › Research › peer-review
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Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage
Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 172, p. 633-651Research output: Contribution to journal › Review › Research › peer-review
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Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In: FEBS Letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In: Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks
Hazlewood, C. & Davies, Michael Jonathan, 1 Aug 1996, In: Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin
He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.Research output: Contribution to journal › Journal article › Research › peer-review
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beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In: Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones
Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals
Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael Jonathan, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael Jonathan, Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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