Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2006
  2. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael Jonathan, 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael Jonathan & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael Jonathan, Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2005
  7. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers

    Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In: Neuropharmacology. 49, 5, p. 669-86 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study

    Heller, S., Davies, Michael Jonathan, Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  15. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael Jonathan, 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael Jonathan, 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael Jonathan, Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Diabetes screening anxiety and beliefs

    Skinner, Timothy, Davies, Michael Jonathan, Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Utility of risk factors when screening for diabetes mellitus

    Tringham, J. R., Davies, Michael Jonathan, Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  21. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael Jonathan, Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2004
  23. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Reactive species formed on proteins exposed to singlet oxygen

    Davies, Michael Jonathan, Jan 2004, In: Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products

    Headlam, H. A. & Davies, Michael Jonathan, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress

    Pattison, D. I. & Davies, Michael Jonathan, 27 Apr 2004, In: Biochemistry. 43, 16, p. 4799-809 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael Jonathan, 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael Jonathan, 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2003
  33. Published

    Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima

    Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan & Smith, N. C., Jun 2003, In: Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Singlet oxygen-mediated damage to proteins and its consequences

    Davies, Michael Jonathan, 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Radical chemistry of epigallocatechin gallate and its relevance to protein damage

    Hagerman, A. E., Dean, R. T. & Davies, Michael Jonathan, 1 Jun 2003, In: Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Hypochlorite-induced oxidation of amino acids, peptides and proteins

    Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

    Woods, A. A., Linton, S. M. & Davies, Michael Jonathan, 1 Mar 2003, In: Biochemical Journal. 370, Pt 2, p. 729-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fragmentation of extracellular matrix by hypochlorous acid

    Woods, A. A. & Davies, Michael Jonathan, 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Mar 2003, In: Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The retina: oxidative stress and diabetes

    van Reyk, D. M., Gillies, M. C. & Davies, Michael Jonathan, 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2002
  46. Published

    Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides

    Hampton, M. B., Morgan, P. E. & Davies, Michael Jonathan, 11 Sep 2002, In: FEBS letters. 527, 1-3, p. 289-92 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In: FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones

    Headlam, H. A. & Davies, Michael Jonathan, 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein

    Knott, H. M., Baoutina, A., Davies, Michael Jonathan & Dean, R. T., 15 Apr 2002, In: Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205