Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2009
  2. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In : Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In : Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

    Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael Jonathan, 1 Jul 2009, In : Biochemical Journal. 421, 1, p. 79-86 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 15 Aug 2009, In : Biochemical Journal. 422, 1, p. 111-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2008
  10. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In : BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The DESMOND educational intervention

    Davies, Michael Jonathan, Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In : Chronic Illness. 4, 1, p. 38-40 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid

    Kennett, E. C. & Davies, Michael Jonathan, 1 Sep 2008, In : Free Radical Biology & Medicine. 45, 5, p. 716-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with type 2 diabetes: Baseline data from the DESMOND randomized controlled trial

    Khunti, K., Skinner, Timothy, Heller, S., Carey, M. E., Dallosso, H. M. & Davies, Michael Jonathan, 1 Dec 2008, In : Diabetic Medicine. 25, 12, p. 1454-1461 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals

    Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael Jonathan, Nov 2008, In : Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In : Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

    Mizdrak, J., Hains, P. G., Truscott, R. J. W., Jamie, J. F. & Davies, Michael Jonathan, 15 Mar 2008, In : Free Radical Biology & Medicine. 44, 6, p. 1108-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jun 2008, In : Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, 5 Aug 2008, In : Biochemistry. 47, 31, p. 8237-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    'Educator talk' and patient change: Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Sep 2008, In : Diabetic Medicine. 25, 9, p. 1117-1120 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation

    Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael Jonathan, May 2008, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2008, In : Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael Jonathan & Witting, P. K., 15 Sep 2008, In : Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study

    Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael Jonathan, 1 Jul 2008, In : Patient Education and Counseling. 72, 1, p. 88-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2007
  29. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

    Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In : F E B S Journal. 274, 6, p. 1530-41 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products

    Gracanin, M. & Davies, Michael Jonathan, 15 May 2007, In : Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism

    Kennett, E. C. & Davies, Michael Jonathan, 15 Apr 2007, In : Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael Jonathan, Dec 2007, In : Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael Jonathan & Truscott, R. J. W., Aug 2007, In : Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro

    Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, 6 Mar 2007, In : FEBS letters. 581, 5, p. 1067-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael Jonathan, 15 Jan 2007, In : Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants

    Skaff, O., Pattison, D. I. & Davies, Michael Jonathan, Dec 2007, In : Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2006
  40. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides

    Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In : B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael Jonathan, 2006, In : E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journalJournal articleResearch

  44. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In : Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael Jonathan, 8 Mar 2006, In : Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael Jonathan, Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In : Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael Jonathan, 1 May 2006, In : Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael Jonathan & Radom, L., 31 Aug 2006, In : Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In : Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael Jonathan, Dec 2006, In : Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2005
  52. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers

    Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, B. E., Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In : Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. The oxidative environment and protein damage

    Davies, Michael Jonathan, 17 Jan 2005, In : B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In : Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205