Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
Effect of Methylglyoxal-Induced Glycation on the Composition and Structure of β-Lactoglobulin and α-Lactalbumin
Krämer, A. C. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 2, p. 699-710 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Oxidation and Protein Unfolding on Cross-Linking of β-Lactoglobulin and α-Lactalbumin
Krämer, A. C., Torreggiani, A. & Davies, Michael J., 2017, In: Journal of Agricultural and Food Chemistry. 65, 47, p. 10258-10269 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges
Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92Research output: Contribution to journal › Review › Research › peer-review
Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins
Moheimani, F., Tan, J. T. M., Brown, B. E., Heather, A. K., van Reyk, D. M. & Davies, Michael J., 2011, In: Journal of Diabetes Research. 2011, p. 851280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin
Nielsen, L. R., Lund, Marianne N., Davies, Michael J., Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways
Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael J., 2021, In: Redox Biology. 48, 15 p., 102202.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte
Murphy, P. G., Davies, Michael J., Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals
Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care
Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael J., 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael J., Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]
Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I
Nobecourt, E., Zeng, J., Davies, Michael J., Brown, B. E., Yadav, S., Barter, P. J. & Rye, K. -., Jun 2008, In: Diabetologia. 51, 6, p. 1008-1017 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification
Sauerland, Max Benjamin & Davies, Michael J., 30 Sep 2022, In: Archives of Biochemistry and Biophysics. 727, 10 p., 109344.Research output: Contribution to journal › Review › Research › peer-review
- Published
Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction
Gentile, C., Kesteven, S., Wu, J., Davies, Michael J., Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment
Pehrsson, M., Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael J., 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064Research output: Contribution to journal › Review › Research › peer-review
- Published
Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes
Ali, S., Taub, N. A., Stone, M. A., Davies, Michael J., Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients
Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael J. & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells
Talib, J. & Davies, Michael J., 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to peroxynitrite impacts the ability of anastellin to modulate the structure of extracellular matrix
He, Jianfei, Chuang, Christine, Hawkins, Clare Louise, Davies, Michael J. & Hägglund, Per Mårten, 2023, In: Free Radical Biology and Medicine. 206, p. 83-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}
Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael J. & Siebuhr, A. S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael J. & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael J. & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?
Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation
Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Redox Biology. 41, 16 p., 101874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragmentation of extracellular matrix by hypochlorous acid
Woods, A. A. & Davies, Michael J., 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Free Radical Research origins
Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article › Research
- Published
Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael J., 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure
Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael J. & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael J., Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
Knott, H. M., Brown, B. E., Davies, Michael J. & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation
Kennett, E. C. & Davies, Michael J., 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Murphy, M. P., Bayir, H., Belousov, V., Chang, C. J., Davies, K. J. A., Davies, Michael J., Dick, T. P., Finkel, T., Forman, H. J., Janssen-Heininger, Y., Gems, D., Kagan, V. E., Kalyanaraman, B., Larsson, N. G., Milne, G. L., Nyström, T., Poulsen, Henrik Enghusen, Radi, R., Van Remmen, H., Schumacker, P. T., Thornalley, P. J., Toyokuni, S., Winterbourn, C. C., Yin, H. & Halliwell, B., 2022, In: Nature Metabolism. 4, 6, p. 651-662Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction
Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael J., Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine
Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael J., 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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