Michael J. Davies

Michael J. Davies

Professor


  1. Published

    Reaction between protein radicals and other biomolecules

    Østdal, H., Davies, Michael J. & Andersen, H. J., 15 Jul 2002, In: Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The retina: oxidative stress and diabetes

    van Reyk, D. M., Gillies, M. C. & Davies, Michael J., 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure

    Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael J. & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

    Zeng, J. & Davies, Michael J., Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Chlorination and nitration of extracellular matrix by inflammatory myeloperoxidase-derived oxidants in the presence of nitrite

    Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 566 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  11. Published

    Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage

    Xu, Shuqi, Chuang, Christine, Malle, E., Gamon, Luke Francis, Hawkins, Clare Louise & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 188, p. 162-174

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Mar 2003, In: Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael J., Jul 2002, In: Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides

    Wright, A., Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 159-61 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques

    Woods, A. A., Linton, S. M. & Davies, Michael J., 1 Mar 2003, In: Biochemical Journal. 370, Pt 2, p. 729-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Fragmentation of extracellular matrix by hypochlorous acid

    Woods, A. A. & Davies, Michael J., 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals

    Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals

    Witting, P. K., Willhite, C. A., Davies, Michael J. & Stocker, R., Dec 1999, In: Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides

    Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 241-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

    Weber, D., Davies, Michael J. & Grune, T., 1 Aug 2015, In: Redox Biology. 5, p. 367-380 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines

    Wang, Y., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., Aug 2022, In: Antioxidants. 11, 8, 22 p., 1616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bio-Activation of Polyether Ether Ketone Using Plasma Immersion Ion Implantation: A Kinetic Model

    Wakelin, E. A., Kondyurin, A. V., Wise, S. G., McKenzie, D. R., Davies, Michael J. & Bilek, M. M. M., 2015, In: Plasma Processes and Polymers.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Temperature Activated Diffusion of Radicals through Ion Implanted Polymers

    Wakelin, E. A., Davies, Michael J., Bilek, M. M. M. & McKenzie, D. R., 2 Dec 2015, In: A C S Applied Materials and Interfaces. 7, 47, p. 26340-26345 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators

    Voss, G. T., de Oliveira, R. L., Davies, Michael J., Domingues, W. B., Campos, V. F., Soares, M. P., Luchese, C., Schiesser, C. H. & Wilhelm, E. A., 2021, In: Journal of Trace Elements in Medicine and Biology. 67, 10 p., 126795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Special issue for the 7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia 2015 Thailand)

    Ungsurungsie, M., Surh, Y., Toyokuni, S. & Davies, Michael J., 2 Oct 2016, In: Free Radical Research. 50, 10, p. 1045-1046

    Research output: Contribution to journalEditorialResearch

  28. Published

    Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development

    Tweeddale, H. J., Hawkins, Clare Louise, Janmie, J. F., Truscott, R. J. W. & Davies, Michael J., Oct 2016, In: Free Radical Research. 50, 10, p. 1116-1130 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)

    Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael J., Bartoszek, A. & Cherkaoui-Malki, M., 2019, In: Free Radical Research. 53, S1, p. 1163-1170

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?

    Truscott, R. J. W., Mizdrak, J., Friedrich, M. G., Hooi, M. Y., Lyons, B., Jamie, J. F., Davies, Michael J., Wilmarth, P. A. & David, L. L., Jun 2012, In: Experimental Eye Research. 99, p. 48-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study

    Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael J., 1 Jul 2008, In: Patient Education and Counseling. 72, 1, p. 88-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Utility of risk factors when screening for diabetes mellitus

    Tringham, J. R., Davies, Michael J., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  33. Published

    Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action

    Tiwari, M. K., Hägglund, Per Mårten, Møller, I. M., Davies, Michael J. & Bjerrum, Morten Jannik, 2019, In: Redox Biology. 26, 15 p., 101262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Early events in copper-ion catalyzed oxidation of α-synuclein

    Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D. E., Davies, Michael J. & Bjerrum, Morten Jannik, 2018, In: Free Radical Biology & Medicine. 121, p. 38-50 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Superoxide radicals have a protective role during H2O2 stress

    Thorpe, G. W., Reodica, M., Davies, Michael J., Heeren, G., Jarolim, S., Pillay, B., Breitenbach, M., Higgins, V. J. & Dawes, I. W., Sep 2013, In: Molecular Biology of the Cell. 24, 18, p. 2876-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite

    Thomas, S. R., Davies, Michael J. & Stocker, R., 1998, In: Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content

    Thallas-Bonke, V., Coughlan, M. T., Tan, A. L., Harcourt, B. E., Morgan, P. E., Davies, Michael J., Bach, L. A., Cooper, M. E. & Forbes, J. M., Jan 2013, In: Nephrology. 18, 1, p. 47-56 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine

    Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael J., 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction

    Talib, J., Kwan, J., Suryo Rahmanto, A., Witting, P. K. & Davies, Michael J., 1 Jan 2014, In: Biochemical Journal. 457, 1, p. 89-97 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells

    Talib, J. & Davies, Michael J., 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Site-specific hypochlorous acid-induced oxidation of recombinant human myoglobin affects specific amino acid residues and the rate of cytochrome b5-mediated heme reduction

    Szuchman-Sapir, A. J., Pattison, D. I., Davies, Michael J. & Witting, P. K., 1 Jan 2010, In: Free Radical Biology & Medicine. 48, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Photo-oxidation-induced inactivation of the selenium-containing protective enzymes thioredoxin reductase and glutathione peroxidase

    Suryo Rahmanto, A., Pattison, D. I. & Davies, Michael J., 15 Sep 2012, In: Free Radical Biology & Medicine. 53, 6, p. 1308-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides

    Suryo Rahmanto, A. & Davies, Michael J., 15 Dec 2011, In: Free Radical Biology & Medicine. 51, 12, p. 2288-99 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Mechanisms of degradation of the natural high-potency sweetener (2R,4R)-monatin in mock beverage solutions

    Storkey, C., Pattison, D. I., Gaspard, D. S., Hagestuen, E. D. & Davies, Michael J., 16 Apr 2014, In: Journal of Agricultural and Food Chemistry. 62, 15, p. 3476-87 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Synthesis and antioxidant capacity of 5-selenopyranose derivatives

    Storkey, C., Davies, Michael J., White, J. M. & Schiesser, C. H., 14 Sep 2011, In: Chemical communications (Cambridge, England). 47, 34, p. 9693-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Prevention of degradation of the natural high potency sweetener (2R,4R)-monatin in mock beverage solutions

    Storkey, C., Pattison, D. I., Koehler, J. A., Gaspard, D. S., Evans, J. C., Hagestuen, E. D. & Davies, Michael J., 2015, In: Food Chemistry. 173, p. 645-651

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach

    Storkey, C., Davies, Michael J. & Pattison, D. I., Aug 2014, In: Free Radical Biology & Medicine. 73, p. 60-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Kinetics of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance

    Storkey, C., Pattison, D. I., Ignasiak, M. T., Schiesser, C. H. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 1049-1056 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Preventing protein oxidation with sugars: scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives

    Storkey, C., Pattison, D. I., White, J. M., Schiesser, C. H. & Davies, Michael J., 19 Nov 2012, In: Chemical Research in Toxicology. 25, 11, p. 2589-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions

    Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper

    Stadler, N., Lindner, R. A. & Davies, Michael J., 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation

    Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael J., May 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Reduced metal ion concentrations in atherosclerotic plaques from subjects with type 2 diabetes mellitus

    Stadler, N., Heeneman, S., Vöö, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J. & Davies, Michael J., Jun 2012, In: Atherosclerosis. 222, 2, p. 512-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy

    Sourris, K. C., Harcourt, B. E., Penfold, S. A., Yap, F. Y. T., Morley, A. L., Morgan, P. E., Davies, Michael J., Baker, S. T., Jerums, G. & Forbes, J. M., 2010, In: Journal of Diabetes Research. 2010, p. 974681

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Processed foods drive intestinal barrier permeability and microvascular diseases

    Snelson, M., Tan, S. M., Clarke, R. E., De Pasquale, C., Thallas-Bonke, V., Nguyen, T. V., Penfold, S. A., Harcourt, B. E., Sourris, K. C., Lindblom, R. S., Ziemann, M., Steer, D., El-Osta, A., Davies, Michael J., Donnellan, L., Deo, P., Kellow, N. J., Cooper, M. E., Woodruff, T. M., Mackay, C. R., Forbes, J. M. & Coughlan, M. T., 2021, In: Science Advances. 7, 14, eabe4841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

    Skjoldager, N., Blanner Bang, M., Rykaer, M., Björnberg, O., Davies, Michael J., Svensson, B., Harris, P. & Hägglund, Per Mårten, Apr 2017, In: Scientific Reports. 7, 10 p., 46282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Diabetes screening anxiety and beliefs

    Skinner, Timothy, Davies, Michael J., Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study

    Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In: Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Dalyb, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Olivere, L., 1 Mar 2011, In: Psychology and Health. 26, 3, p. 321-335 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Depressive symptoms in the first year from diagnosis of Type 2 diabetes: Results from the DESMOND trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 965-967 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    'Educator talk' and patient change: Some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial

    Skinner, Timothy, Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Sep 2008, In: Diabetic Medicine. 25, 9, p. 1117-1120 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

    Skaff, O., Pattison, D. I., Morgan, P. E., Bachana, R., Jain, V. K., Priyadarsini, K. I. & Davies, Michael J., 1 Jan 2012, In: Biochemical Journal. 441, 1, p. 305-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

    Skaff, O., Pattison, D. I. & Davies, Michael J., 15 Aug 2009, In: Biochemical Journal. 422, 1, p. 111-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study

    Skaff, O., Pattison, D. I. & Davies, Michael J., 5 Aug 2008, In: Biochemistry. 47, 31, p. 8237-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants

    Skaff, O., Pattison, D. I. & Davies, Michael J., Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin

    Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Feb 1998, In: Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues

    Silvester, J. A., Timmins, G. S. & Davies, Michael J., 15 Mar 1998, In: Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode

    Silva, E., Barrias, P., Fuentes-Lemus, E., Tirapegui, C., Aspee, A., Carroll, L., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 131, p. 133-143

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Influence of O-2 on riboflavin-mediated photo-oxidation of lysozyme: [Meeting Abstract]

    Silva, E., Tirapegui, C., Fuentes-Lemus, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Caroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S58-S59 P-46.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  72. Published

    The role of RNA oxidation in islet dysfunction in Type 2 diabetes

    Sileikaite, Inga, Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

    Research output: Contribution to journalConference abstract in journalResearch

  73. Published

    Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

    Sies, H., Belousov, V. V., Chandel, N. S., Davies, Michael J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M. & Winterbourn, C., 2022, In: Nature Reviews Molecular Cell Biology. 23, p. 499–515

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    Reaction of quinones with proteins: Kinetics of adduct formation, effects on enzymatic activity and protein structure, and potential reversibility of modifications

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 137, p. 169-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael J., 2020, In: Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Kinetics and biological consequences of quinone-induced protein adduction: [Meeting Abstract]

    Shu, N., Lorentzen, Lasse Gøbel & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S55-S55 P-34.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  77. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]

    Shu, N. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.

    Research output: Contribution to journalConference abstract in journalResearch

  78. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]

    Shu, N., Hägglund, Per Mårten & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.

    Research output: Contribution to journalConference abstract in journalResearch

  79. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael J., Jan 2020, In: Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Protein oxidation injury occurs during pediatric cardiopulmonary bypass

    Sheil, M. L., Luxford, C., Davies, Michael J., Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Electrophile versus oxidant modification of cysteine residues: Kinetics as a key driver of protein modification

    Sauerland, Max Benjamin & Davies, Michael J., 30 Sep 2022, In: Archives of Biochemistry and Biophysics. 727, 109344.

    Research output: Contribution to journalReviewResearchpeer-review

  83. Published

    Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

    Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Kinetic data for the reactions of alpha,beta-unsaturated aldehydes shed light on their molecular targets and biological effects

    Sauerland, M., Gamon, Luke Francis & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 596 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  85. Published

    Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications

    Rykær, M., Svensson, B., Davies, Michael J. & Hägglund, Per Mårten, 3 Nov 2017, In: Journal of Proteome Research. 16, 11, p. 3978-3988 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins

    Rossi, C., Fuentes Lemus, Eduardo & Davies, Michael J., 2022, In: Food Chemistry. 385, 7 p., 132667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation

    Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael J., Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael J., 15 Jun 2008, In: Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael J., Jan 2010, In: Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Degradation of extracellular matrix and its components by hypobromous acid

    Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

    Rees, M. D., Bottle, S. E., Fairfull-Smith, K. E., Malle, E., Whitelock, J. M. & Davies, Michael J., 1 Jul 2009, In: Biochemical Journal. 421, 1, p. 79-86 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS

    Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro

    Rashid, I., van Reyk, D. M. & Davies, Michael J., 6 Mar 2007, In: FEBS Letters. 581, 5, p. 1067-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Selenium-containing amino acids as direct and indirect antioxidants

    Rahmanto, A. S. & Davies, Michael J., Nov 2012, In: I U B M B Life. 64, 11, p. 863-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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