Mette Rosenkilde

Mette Rosenkilde

Professor

Member of:


    1. 2023
    2. Published

      Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

      Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Adhesion G protein‐coupled receptor's structure, function and role in biology—Status from the 10th adhesion GPCR workshop in Copenhagen, 2022

      Rosenkilde, Mette & Mathiasen, Signe, 2023, In: Basic & clinical pharmacology & toxicology. 133, 4, p. 281-284

      Research output: Contribution to journalEditorialResearchpeer-review

    4. Published

      Amantadine for COVID-19 treatment (ACT) study: a randomized, double-blinded, placebo-controlled clinical trial

      Weis, Nina, Bollerup, S., Sund, J. D., Glamann, J. B., Vinten, C., Jensen, L. R., Sejling, Christoffer, Kledal, T. N. & Rosenkilde, Mette, 2023, In: Clinical Microbiology and Infection. 29, 10, p. 1313-1319 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5

      Larsen, Olav, Schuermans, S., Walser, Anna Louise Silvia, Louka, S., Lillethorup, I. A., Våbenø, J., Qvortrup, K., Proost, P. & Rosenkilde, Mette, 2023, In: FEBS Letters. 597, 24, p. 3049-3060

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation

      Goth, C. K., Mehta, A. Y., McQuillan, A. M., Baker, K. J., Hanes, M. S., Park, S. S., Stavenhagen, K., Hjortø, Gertrud Malene, Heimburg-Molinaro, J., Chaikof, E. L., Rosenkilde, Mette & Cummings, R. D., 2023, In: Cell Chemical Biology. 30, 8, p. 893-905.e7

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      GIP reduces osteoclast activity and improves osteoblast survival in primary human bone cells

      Hansen, M. S., Soe, K., Christensen, L. L., Fernandez-Guerra, P., Hansen, N. W., Wyatt, R. A., Martin, C., Hardy, R. S., Andersen, T. L., Olesen, J. B., Hartmann, Bolette, Rosenkilde, Mette, Kassem, M., Rauch, A., Gorvin, C. M. & Frost, M., 2023, In: European Journal of Endocrinology. 188, 1, 14 p., 004.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      GPR162 is a beta cell CART receptor

      Lindqvist, A., Abels, M., Shcherbina, L., Ngara, M., Kryvokhyzha, D., Chriett, S., Riva, M., Fajul, A., Barghouth, M., Luan, C., Eliasson, L., Larsen, Olav, Rosenkilde, Mette, Zhang, E., Renström, E. & Wierup, N., 2023, In: iScience. 26, 12, 15 p., 108416.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

      Foo, C. X., Bartlett, S., Chew, K. Y., Ngo, M. D., Bielefeldt-Ohmann, H., Arachchige, B. J., Matthews, B., Reed, S., Wang, R., Smith, C., Sweet, M. J., Burr, L., Bisht, K., Shatunova, S., Sinclair, J. E., Parry, R., Yang, Y., Lévesque, J. P., Khromykh, A., Rosenkilde, M. M. & 2 others, Short, K. R. & Ronacher, K., 2023, In: The European respiratory journal. 61, 3, 15 p., 2201306.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Glycine: a long-sought novel ligand for GPR158

      Rosenkilde, Mette & Mathiesen, Jesper M., 2023, In: Trends in Pharmacological Sciences. 44, 8, p. 489-491

      Research output: Contribution to journalLetterResearchpeer-review

    11. Published

      Identification of a Salt Bridge That Is Functionally Important for Chemokine Receptor CXCR1 but not CXCR2

      Våbenø, J., Oliva-Santiago, M., Jørgensen, Astrid Sissel, Karlshøj, S. & Rosenkilde, Mette, 2023, In: ACS Pharmacology and Translational Science. 6, 8, p. 1120-1128 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Ligand entry pathways control the chemical space recognized by GPR183

      Kjær, Viktoria Madeline Skovgaard, Stępniewski, T. M., Medel-Lacruz, B., Reinmuth, L., Ciba, Marija, Ulven, Elisabeth Rexen, Bonomi, M., Selent, J. & Rosenkilde, Mette, 2023, In: Chemical Science. 14, 39, p. 10671-10683

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

      Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Loss of Adgra3 causes obstructive azoospermia with high penetrance in male mice

      Nybo, Maja Lind, Kvam, J. M., Nielsen, J. E., Frederiksen, H., Spiess, Katja, Jensen, Kristian HR, Gadgaard, S., Walser, Anna Louise Silvia, Thomsen, J. S., Cowin, P., Juul, Anders, Jensen, M. B. & Rosenkilde, Mette, 2023, In: FASEB Journal. 37, 2, 13 p., 22781.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

      Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

      Mavri, M., Glišić, S., Senćanski, M., Vrecl, M., Rosenkilde, Mette, Spiess, Katja & Kubale, V., 2023, In: Cellular and Molecular Biology Letters. 28, 1, 19 p., 14.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

      Ewart, G., Bobardt, M., Bentzen, Bo Hjorth, Yan, Y., Thomson, A., Klumpp, K., Becker, S., Rosenkilde, Mette, Miller, M. & Gallay, P., 2023, In: PLoS Pathogens. 19, 8 August, 20 p., e1011328.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

      Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Re-routing GPR56 signalling using Gα12/13 G protein chimeras

      Faas, Felix, Nørskov, Amalie, Holst, Peter Johannes, Andersson, A. M., Qvortrup, K., Mathiasen, Signe & Rosenkilde, Mette, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 378-389

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      The Secretome of Parental and Bone Metastatic Breast Cancer Elicits Distinct Effects in Human Osteoclast Activity after Activation of β2 Adrenergic Signaling

      Conceição, F., Sousa, D. M., Tojal, S., Lourenço, C., Carvalho-Maia, C., Estevão-Pereira, H., Lobo, J., Couto, M., Rosenkilde, Mette, Jerónimo, C. & Lamghari, M., 2023, In: Biomolecules. 13, 4, 25 p., 622.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

      Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

      Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

      Research output: Contribution to journalReviewResearchpeer-review

    23. Published

      The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

      Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Therapeutic targeting of HCMV-encoded chemokine receptor US28: Progress and challenges

      Berg, Christian & Rosenkilde, Mette, 2023, In: Frontiers in Immunology. 14, 8 p., 1135280.

      Research output: Contribution to journalReviewResearchpeer-review

    25. Published

      “Glyco-sulfo barcodes” regulate chemokine receptor function

      Verhallen, L., Lackman, Jarkko Juhani, Wendt, R., Gustavsson, Martin, Yang, Zhang, Narimatsu, Yoshiki, Sørensen, Daniel Madriz, Lafferty, K. M., Gouwy, M., Marques, P. E., Hjortø, Gertrud Malene, Rosenkilde, Mette, Proost, P. & Goth, C. K., 2023, In: Cellular and Molecular Life Sciences. 80, 2, 18 p., 55.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 3361