Joachim Størling

Joachim Størling

Affiliated Associate Professor


Publication year:
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1 - 44 out of 44Page size: 500
  1. 2023
  2. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, Joachim, 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cross-sectional study investigating the association between inflammatory biomarkers and neuropathy in adolescents with type 1 diabetes

    Rasmussen, V. F., Hirschberg Jensen, V., Thrysøe, M., Vestergaard, E. T., Størling, Joachim & Kristensen, K., 2023, In: BMJ Open. 13, 10, 10 p., e074992.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Features characterising cardiac autonomic neuropathy in diabetes using ensembled classification

    Nedergaard, R. B., Scott, M., Wegeberg, A., Okdahl, T., Størling, Joachim, Brock, Birgitte, Drewes, A. M. & Brock, C., 2023, In: Clinical Neurophysiology. 154, p. 200-208

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Systemic Cytokine Expression in Diabetes Is Associated with Prolonged Gastrointestinal Transit Times and Cardinal Gastroparesis Symptoms

    Okdahl, T., Wegeberg, A., Jensen, A. B. H., Jensen, S. T., Andersen, H. R. P., Størling, Joachim, Brock, Birgitte & Brock, C., 2023, In: Biomedicines. 11, 4, 11 p., 1027.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2022
  10. Published

    Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes

    Wegeberg, A. M., Okdahl, T., Riahi, S., Ejskjaer, N., Pociot, Flemming, Størling, Joachim, Brock, Birgitte & Brock, C., 2022, In: Cardiovascular Diabetology. 21, 1, 10 p., 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Increased liver fat associates with severe metabolic perturbations in low birth weight men

    Brøns, C., Thuesen, Anne Cathrine Baun, Elingaard-Larsen, L. O., Justesen, L., Jensen, Rasmus Tanderup, Henriksen, Nicolai Stevns, Juel, H. B., Størling, Joachim, Ried-Larsen, M., Sparks, L. M., van Hall, Gerrit, Danielsen, E. R., Hansen, Torben & Vaag, Allan, 2022, In: European Journal of Endocrinology. 186, 5, p. 511-521 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

    Lopes de Melo, J. M., Laursen, J. C., Søndergaard-Heinrich, N., Bull Rasmussen, I. K., Hansen, C. S., Frimodt-Møller, M., Rossing, Peter & Størling, Joachim, 2022, In: Heliyon. 8, 12, 7 p., e12304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Low-grade inflammation in type 2 diabetes: A cross-sectional study from a Danish diabetes outpatient clinic

    Okdahl, T., Wegeberg, A. M., Pociot, Flemming, Brock, Birgitte, Størling, Joachim & Brock, C., 2022, In: BMJ Open. 12, 12, 10 p., e062188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells

    Kaur, S., Frørup, C., Mirza, A. H., Fløyel, T., Yarani, R., Colli, M. L., Johannesen, Jesper, Størling, Joachim, Eizirik, D. L. & Pociot, Flemming, 2022, In: Non-coding RNA. 8, 5, 19 p., 69.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    Skap2, a candidate gene for type 1 diabetes, regulates b-cell apoptosis and glycemic control in newly diagnosed patients

    Fløyel, T., Meyerovich, K., Prause, Michala Cecilie Burstein, Kaur, S., Frørup, C., Mortensen, H. B., Nielsen, L. B., Pociot, Flemming, Cardozo, A. K. & Størling, Joachim, 2021, In: Diabetes. 70, 2, p. 464-476 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

    Kaur, S., Mirza, A. H., Overgaard, A. J., Pociot, Flemming & Størling, Joachim, 2021, In: Frontiers in Genetics. 12, 630109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: A randomised, double-blind, placebo-controlled crossover trial

    Laursen, J. C., Søndergaard-Heinrich, N., de Melo, J. M. L., Haddock, B., Rasmussen, I. K. B., Safavimanesh, F., Hansen, C. S., Størling, Joachim, Larsson, Henrik Bo Wiberg, Groop, P., Frimodt-Møller, M., Andersen, U. B. & Rossing, Peter, 2021, In: EClinicalMedicine. 37, 10 p., 100895.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Associations between postprandial gut hormones and markers of bone remodeling

    Jensen, N. W., Clemmensen, K. K. B., Jensen, M. M., Pedersen, H., Færch, K., Diaz, L. J., Quist, J. S. & Størling, Joachim, 2021, In: Nutrients. 13, 9, 9 p., 3197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Cathepsin c regulates cytokine-induced apoptosis in β-cell model systems

    Fløyel, T., Frørup, C., Størling, Joachim & Pociot, Flemming, 2021, In: Genes. 12, 11, 1694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Effect of liraglutide on expression of inflammatory genes in type 2 diabetes

    Zobel, E. H., Ripa, Rasmus Sejersten, von Scholten, B. J., Rotbain Curovic, V., Kjær, Andreas, Hansen, T. W., Rossing, Peter & Størling, Joachim, 2021, In: Scientific Reports. 11, 18522.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

    Frørup, C., Mirza, A. H., Yarani, R., Nielsen, L. B., Mathiesen, Elisabeth, Damm, Peter, Svare, J., Engelbrekt, C., Størling, Joachim, Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Kaur, S., 2021, In: Frontiers in Immunology. 12, 744509.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  25. 2020
  26. Published

    Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

    Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, Joachim & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

    Okdahl, T., Brock, C., Floyel, T., Wegeberg, A. L., Jakobsen, P. E., Ejskjaer, N., Pociot, Flemming, Brock, Birgitte & Størling, Joachim, 2020, In: Clinical Endocrinology. 93, 4, p. 419-428

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes

    Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.

    Research output: Contribution to journal › Conference abstract in journal › Research

  30. Published

    Systemic TNF alpha correlates with residual beta-cell function in children and adolescents newly diagnosed with type 1 diabetes

    Overgaard, A. J., Madsen, J. O. B., Pociot, Flemming, Johannesen, Jesper & Størling, Joachim, 2020, In: BMC Pediatrics. 20, 1, 6 p., 446.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The Rac2 GTPase contributes to cathepsin H-mediated protection against cytokine-induced apoptosis in insulin-secreting cells

    Floyel, T., Mirza, A. H., Kaur, S., Frorup, C., Yarani, R., Størling, Joachim & Pociot, Flemming, 2020, In: Molecular and Cellular Endocrinology. 518, 11 p., 110993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2016
  33. Published

    Cytokines and Pancreatic β-Cell Apoptosis

    Berchtold, L. A., Prause, Michala Cecilie Burstein, Størling, Joachim & Mandrup-Poulsen, Thomas, 28 Jun 2016, Advances in Clinical Chemistry. Academic Press, Vol. 75. p. 99-158 60 p. (Advances in Clinical Chemistry, Vol. 75).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  34. Published

    TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

    Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus

    Kaur, S., Mirza, A. H., Brorsson, C. A., Fløyel, T., Størling, Joachim, Mortensen, H. B., Pociot, Flemming & Hvidoere International Study Group, H. I. S. G., 5 Jan 2016, In: Molecular and Cellular Endocrinology. 419, p. 83-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression

    Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Størling, Joachim & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. 2014
  38. Published

    Skeletal muscle apolipoprotein B expression reduces muscular triglyceride accumulation

    Bartels, Emil Daniel, Ploug, Thorkil, Størling, Joachim, Mandrup-Poulsen, Thomas & Nielsen, L. B., Jun 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 4, p. 351-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2012
  40. Published

    TiSH--a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

    Engholm-Keller, K., Birck, P., Størling, Joachim, Pociot, Flemming, Mandrup-Poulsen, Thomas & Larsen, M. R., 22 Oct 2012, In: International Journal of Proteomics. 75, 18, p. 5749-61 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines

    Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, Mandrup-Poulsen, Thomas, 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2011
  43. Published

    Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway.

    Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, Michala Cecilie Burstein, Berggren, P. & Mandrup-Poulsen, Thomas, Aug 2011, In: Endocrinology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro

    Lewis, E. C., Blaabjerg, L., Størling, Joachim, Ronn, S. G., Mascagni, P., Dinarello, C. A. & Mandrup-Poulsen, Thomas, May 2011, In: Molecular Medicine. 17, 5-6, p. 369-377 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Apolipoprotein CIII Reduces Proinflammatory Cytokine-Induced Apoptosis in Rat Pancreatic Islets via the Akt Prosurvival Pathway

    Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, M. C., Berggren, P. & Mandrup-Poulsen, Thomas, 2011, In: Endocrinology. 152, 8, p. 3040-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

    Berchtold, L. A., Størling, Z. M., Ortis, F., Lage, K., Bang-Berthelsen, C., Bergholdt, R., Hald, J., Brorsson, C. A., Eizirik, D. L., Pociot, Flemming, Brunak, Søren & Størling, Joachim, 2011, In: PNAS Early Edition. 108, 37, p. E681-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2009
  48. Published

    Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

    Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Interleukin-1 beta targeted therapy for type 2 diabetes

    Maedler, K., Dharmadhikari, G., Schumann, D. M. & Størling, Joachim, 2009, In: Expert Opinion on Biological Therapy. 9, 9, p. 1177-1188 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2007
  51. Published

    Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

    Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2006
  53. Published

    IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

    Petersen, L. G., Størling, Joachim, Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2005
  55. Published

    Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

    Larsen, L., Størling, Joachim, Darville, M., Eizirik, D. L., Bonny, C., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Dec 2005, In: Diabetologia. 48, 12, p. 2582-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

    Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 20720546