Jesper Tranekjær Jørgensen

Jesper Tranekjær Jørgensen

Assistant professor


  1. 2021
  2. Published

    Direct Cu-mediated aromatic 18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging.

    García Vázquez, Rocío, Battisti, Umberto Maria, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Hvass, Lars, Stares, D. L., Petersen, I. N., Crestey, F., Löffler, A., Svatunek, D., Kristensen, Jesper Langgaard, Mikula, H. & Herth, Matthias Manfred, Jul 2021, In: Chemical Science. 12, 35, p. 11668-11675

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Development of the First Aliphatic 18F-Labeled Tetrazine Suitable for Pretargeted PET Imaging-Expanding the Bioorthogonal Tool Box

    Battisti, Umberto Maria, Bratteby, K., Jørgensen, Jesper Tranekjær, Hvass, Lars, Shalgunov, Vladimir, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15297–15312

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Direct Cu-mediated aromatic18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

    García Vázquez, Rocío, Battisti, Umberto Maria, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Hvass, Lars, Stares, D. L., Petersen, I. N., Crestey, F., Löffler, A., Svatunek, D., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Chemical Science. 12, 35, p. 11668-11675

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry

    Steen, E. J. L., Jørgensen, Jesper Tranekjær, Denk, C., Battisti, Umberto Maria, Norregaard, K., Edem, P. E., Bratteby, K., Shalgunov, Vladimir, Wilkovitsch, M., Svatunek, D., Poulie, Christian Bernard Matthijs, Hvass, Lars, Simon, M., Wanek, T., Rossin, R., Robillard, M., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: ACS Pharmacology & Translational Science. 4, 2, p. 824-833 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma

    Simón, M., Jørgensen, Jesper Tranekjær, Juhl, Karina & Kjær, Andreas, 2021, In: OncoTarget. 12, 14, p. 1366-1376 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    18F-FDG positron emission tomography and diffusion-weighted magnetic resonance imaging for response evaluation of nanoparticle-mediated photothermal therapy

    Simón, M., Jørgensen, Jesper Tranekjær, Norregaard, K. & Kjær, Andreas, 2020, In: Scientific Reports. 10, 1, 9 p., 7595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evaluation of a 68Ga-Labeled DOTA-Tetrazine as a PET Alternative to 111In-SPECT Pretargeted Imaging

    Edem, P. E., Jørgensen, Jesper Tranekjær, Norregaard, K., Rossin, R., Yazdani, A., Valliant, J. F., Robillard, M., Herth, Matthias Manfred & Kjær, Andreas, 2020, In: Molecules. 25, 3, 14 p., 463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Johann, K., Norregaard, K., Sohr, B., Svatunek, D., Birke, A., Shalgunov, Vladimir, Edem, P. E., Rossin, R., Seidl, C., Schmid, F., Robillard, M. S., Kristensen, Jesper Langgaard, Mikula, H., Barz, M., Kjær, Andreas & Herth, Matthias Manfred, 2020, In: ACS NANO. 14, 1, p. 568-584

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2019
  13. Published

    Fractionated photothermal therapy in a murine tumor model: comparison with single dose

    Simon Martin, Marina, Norregaard, K., Jørgensen, Jesper Tranekjær, Oddershede, L. B. & Kjær, Andreas, 18 Jul 2019, In: International Journal of Nanomedicine (Online). 14, p. 5369-5379 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    <p>Fractionated photothermal therapy in a murine tumor model: comparison with single dose</p>

    Simón, M., Nørregaard, K., Jørgensen, Jesper Tranekjær, Oddershede, L. B. & Kjær, Andreas, Jul 2019, In: International Journal of Nanomedicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Pretargeted PET imaging using a dual click F-18-labeling strategy: [Meeting Abstract]

    Steen, J., Denk, C., Jørgensen, Jesper Tranekjær, Norregard, K., Rossin, R., Wilkovitsch, M., Svatunek, D., Edem, P., Kuntner, C., Wanek, T., Robillard, M., Kristensen, Jesper Langgaard, Kjær, Andreas, Mikula, H. & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S22-S23 O-08.

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging: [Meeting Abstract]

    Steen, J., Norregard, K., Johann, K., Jørgensen, Jesper Tranekjær, Svatunek, D., Birke, A., Edem, P., Rossin, R., Seidl, C., Schmid, F., Robillard, M., Mikula, H., Kristensen, Jesper Langgaard, Barz, M., Kjær, Andreas & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S109-S110

    Research output: Contribution to journalConference abstract in journalResearch

  17. Published

    Improved radiosynthesis and preliminary in vivo evaluation of the 11 C-labeled tetrazine [ 11 C]AE-1 for pretargeted PET imaging

    Stéen, E. J. L., Jørgensen, Jesper Tranekjær, Petersen, I. N., Nørregaard, K., Lehel, S., Shalgunov, Vladimir, Birke, A., Edem, P. E., L'Estrade, E. T., Hansen, H. D., Villadsen, J., Erlandsson, M., Ohlsson, T., Yazdani, A., Valliant, J. F., Kristensen, Jesper Langgaard, Barz, M., Knudsen, Gitte Moos, Kjær, Andreas & Herth, Matthias Manfred, 1 Jan 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 8, p. 986-990

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2018
  19. Published

    Pretargeting in nuclear imaging and radionuclide therapy: Improving efficacy of theranostics and nanomedicines

    Stéen, E. J. L., Edem, P. E., Nørregaard, K., Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Kjær, Andreas & Herth, Matthias Manfred, Oct 2018, In: Biomaterials. 179, p. 209-245 37 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Non-invasive Early Response Monitoring of Nanoparticle-assisted Photothermal Cancer Therapy Using 18F-FDG, 18F-FLT, and 18F-FET PET/CT Imaging

    Jørgensen, Jesper Tranekjær, Nørregaard, K., Simon Martin, Marina, Oddershede, L. B. & Kjær, Andreas, 27 Apr 2018, In: Nanotheranostics. 2, 3, p. 201-210

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts

    Christensen, E., Henriksen, J. R., Jørgensen, Jesper Tranekjær, Amitay, Y., Shmeeda, H., Gabizon, A. A., Kjær, Andreas, Andresen, T. L. & Hansen, Anders Elias, 2018, In: International Journal of Nanomedicine. 13, p. 7647-7656

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Liposome accumulation in irradiated tumors display important tumor and dose dependent differences

    Hansen, Anders Elias, Fliedner, Frederikke Petrine, Henriksen, J. R., Jørgensen, Jesper Tranekjær, Clemmensen, Andreas Høeg, Børresen, Betina, Elema, D. R., Kjær, Andreas & Andresen, T. L., 2018, In: Nanomedicine: Nanotechnology, Biology and Medicine. 14, 1, p. 27-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2017
  24. Published

    18F-FDG PET/CT-based early treatment response evaluation of nanoparticle-assisted photothermal cancer therapy

    Norregaard, K., Jørgensen, Jesper Tranekjær, Simon Martin, Marina, Melander, F., Kristensen, Lotte Kellemann, Bendix, Poul Martin, Andresen, T. L., Oddershede, L. B. & Kjær, Andreas, 24 May 2017, In: PLOS ONE. 12, 5, e0177997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Using Optically Manipulated Metallic Nanoparticles for Cancer Treatment

    Nørregaard, K., Jørgensen, Jesper Tranekjær, Kjær, Andreas, Samadi, A., Bendix, Poul Martin & Oddershede, L. B., 2 Apr 2017, Optical Trapping Applications 2017: Optical Manipulation Applications III (OtTu2E). San Diego, California, USA: Optical Society of America, OtTuE.4

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  26. 2016
  27. Published

    64Cu-ATSM Reflects pO2 Levels in Human Head and Neck Cancer Xenografts but Not in Colorectal Cancer Xenografts: Comparison with 64CuCl2

    Li, F., Jørgensen, Jesper Tranekjær, Forman, Julie Lyng, Hansen, Anders Elias & Kjær, Andreas, Mar 2016, In: Journal of Nuclear Medicine. 57, 3, p. 437-443 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma

    Persson, M., Nedergaard, M. K., Brandt-Larsen, M., Skovgaard, D., Jørgensen, Jesper Tranekjær, Michaelsen, Signe Regner, Madsen, J., Lassen, Ulrik Niels, Poulsen, Hans Skovgaard & Kjær, Andreas, Feb 2016, In: Journal of Nuclear Medicine. 57, 2, p. 272-278 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The use of matrigel has no influence on tumor development or PET imaging in FaDu human head and neck cancer xenografts

    Fliedner, Frederikke Petrine, Hansen, Anders Elias, Jørgensen, Jesper Tranekjær & Kjær, Andreas, 14 Jan 2016, In: BMC Medical Imaging. 16, 8 p., 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Single Particle and PET-based Platform for Identifying Optimal Plasmonic Nano-Heaters for Photothermal Cancer Therapy

    Jørgensen, Jesper Tranekjær, Nørregaard, K., Tian, P., Bendix, Poul Martin, Kjær, Andreas & Oddershede, L. B., 2016, In: Scientific Reports. 6, 10 p., 30076.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2015
  32. Published

    The impact of weakly bound (89)Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection

    Severin, G. W., Jørgensen, Jesper Tranekjær, Wiehr, S., Rolle, A., Hansen, Anders Elias, Maurer, A., Hasenberg, M., Pichler, B., Kjær, Andreas & Jensen, A. I., Apr 2015, In: Nuclear Medicine and Biology. 42, 4, p. 360-368 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Pharmacokinetic Analysis of 64Cu-ATSM Dynamic PET in Human Xenograft Tumors in Mice

    Li, F., Jørgensen, Jesper Tranekjær, Madsen, J. & Kjær, Andreas, 27 Mar 2015, In: Diagnostics. 5, 2, p. 96-112 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Comparison of the Photothermal Efficiency of Different Types of Plasmonic Nanoparticles in vitro and in vivo

    Nørregaard, K., Jørgensen, Jesper Tranekjær, Bendix, Poul Martin, Kjær, Andreas & Oddershede, L. B., 27 Jan 2015, In: Biophysical Journal. 108, 2, p. 171a

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Automated synthesis and PET evaluation of both enantiomers of [(18)F]FMISO

    Revunov, E., Jørgensen, Jesper Tranekjær, Jensen, A. I., Hansen, Anders Elias, Severin, G. W., Kjær, Andreas & Zhuravlev, F., 2015, In: Nuclear Medicine and Biology. 42, 4, p. 413-419 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2014
  37. Published

    Kinetic modeling in PET imaging of hypoxia

    Li, F., Jørgensen, Jesper Tranekjær, Hansen, Anders Elias & Kjær, Andreas, 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 6, p. 490-506 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2013
  39. Published

    High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers

    Jørgensen, Jesper Tranekjær, Persson, M., Madsen, J. & Kjær, Andreas, Apr 2013, In: Nuclear Medicine and Biology. 40, 3, p. 345-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2012
  41. Published

    Importance of Attenuation Correction (AC) for Small Animal PET Imaging

    El Ali, Henrik H., Bodholdt, R. P., Jørgensen, Jesper Tranekjær, Myschetzky, R. S. M. & Kjær, Andreas, 9 Oct 2012, In: Diagnostics. 2, 4, p. 42-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    (18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers

    Hag, Anne Mette Fisker, Pedersen, S. F., Christoffersen, Christina, Binderup, Tina, Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Skovgaard, D., Ripa, Rasmus Sejersten & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50908

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    64Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry

    Hansen, Anders Elias, Kristensen, Annemarie T., Jørgensen, Jesper Tranekjær, McEvoy, Fintan, Busk, M., Kogel, A. J. V. D., Bussink, J., Engelholm, S. A. & Kjær, Andreas, 2012, In: Radiation Oncology. 7, 8 p., 89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

    Persson, M., Madsen, J., Østergaard, S., Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Juhl, Karina, Lehmann, C., Ploug, Michael & Kjær, Andreas, 2012, In: Journal of Nuclear Medicine. 53, 1, p. 138-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2011
  46. Published

    Hypoxia-inducible factors - regulation, role and comparative aspects in tumourigenesis

    Hansen, Anders Elias, Kristensen, Annemarie T., Law, I., Jørgensen, Jesper Tranekjær & Engelholm, S. A., 2011, In: Veterinary and Comparative Oncology. 9, 1, p. 16-37 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Molecular Imaging with Small Animal PET/CT

    Binderup, Tina, El-Ali, H. H., Skovgaard, D., Wessel, Mette Munk, Li, F., Hesse, B., Jørgensen, Jesper Tranekjær, Kjær, Andreas, Ambrosini, V., Binderup, T., El Ali, H. H., Ambrosini, V., Skovgaard, D., Munk Jensen, M., Li, F., Hesse, B., Jørgensen, J. T. & Kjær, Andreas, 2011, In: Current Medical Imaging Reviews. 7, 3, p. 234-47 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2008
  49. Published
  50. 2006
  51. Published

    Xanthosine utilization in Salmonella enterica serovar Typhimurium is recovered by a single aspartate-to-glycine substitution in xanthosine phosphorylase.

    Hansen, M. R., Jørgensen, Jesper Tranekjær & Dandanell, Gert, 2006, In: Journal of Bacteriology. 188, 11, p. 4153-7

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 986715