Helena Safavi

Helena Safavi

Associate Professor


  1. 2023
  2. Published

    A toxin-based approach to neuropeptide and peptide hormone discovery

    Koch, T. L., Torres, Joshua, Baskin, R. P., Salcedo, P. F., Chase, K., Olivera, B. M. & Safavi, Helena, 2023, In: Frontiers in Molecular Neuroscience. 16, 14 p., 1176662.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2022
  4. Published

    Integrating Venom Peptide Libraries Into a Phylogenetic and Broader Biological Framework

    Chase, K., Watkins, M., Safavi, Helena & Olivera, B. M., 2022, In: Frontiers in Molecular Biosciences. 9, 16 p., 784419.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Symmetric and asymmetric receptor conformation continuum induced by a new insulin

    Xiong, X., Blakely, A., Kim, J. H., Menting, J. G., Schäfer, I. B., Schubert, H. L., Agrawal, R., Gutmann, T., Delaine, C., Zhang, Y. W., Artik, G. O., Merriman, A., Eckert, D., Lawrence, M. C., Coskun, Ü., Fisher, S. J., Forbes, B. E., Safavi, Helena, Hill, C. P. & Chou, D. H. C., 2022, In: Nature Chemical Biology. 18, 5, p. 511-519

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Unconventional insulins from predators and pathogens

    Laugesen, S. H., Chou, D. H. C. & Safavi, Helena, 2022, In: Nature Chemical Biology. 18, 7, p. 688-697

    Research output: Contribution to journalReviewpeer-review

  7. 2021
  8. Published

    DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system

    Bertelsen, A. B., Hackney, Celeste Menuet, Bayer, C. N., Kjelgaard, L. D., Rennig, M., Christensen, B., Sørensen, E. S., Safavi, Helena, Wulff, T., Ellgaard, Lars & Nørholm, M. H. H., 2021, In: Microbial Biotechnology. 14, 6, p. 2566-2580 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. 2020
  10. Published

    A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

    Xiong, X., Menting, J. G., Disotuar, M. M., Smith, N. A., Delaine, C. A., Ghabash, G., Agrawal, R., Wang, X., He, X., Fisher, S. J., MacRaild, C. A., Norton, R. S., Gajewiak, J., Forbes, B. E., Smith, B. J., Safavi, Helena, Olivera, B., Lawrence, M. C. & Chou, D. H. C., 2020, In: Nature Structural and Molecular Biology. 27, p. 615-624

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

    Bjørn-Yoshimoto, Walden, Ramiro, Iris Bea L. , Yandell, M., McIntosh, J. M., Olivera, B. M., Ellgaard, Lars & Safavi, Helena, 2020, In: Biomedicines. 8, 8, 22 p., 235.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Transcriptomic Profiling Reveals Extraordinary Diversity of Venom Peptides in Unexplored Predatory Gastropods of the Genus Clavus

    Lu, A., Watkins, M., Li, Q., Robinson, S. D., Concepcion, G. P., Yandell, M., Weng, Z., Olivera, B. M., Safavi, Helena & Fedosov, A. E., 2020, In: Genome Biology and Evolution. 12, 5, p. 684-700 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2019
  14. Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

    Ahorukomeye, P., Disotuar, M. M., Gajewiak, J., Karanth, S., Watkins, M., Robinson, S. D., Flórez Salcedo, P., Smith, N. A., Smith, B. J., Schlegel, A., Forbes, B. E., Olivera, B., Hung-Chieh Chou, D. & Safavi, Helena, 2019, In: eLife. 8, 28 p., e41574.

    Research output: Contribution to journalJournal articlepeer-review

  15. Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways

    Safavi, Helena, Brogan, S. E. & Olivera, B. M., 2019, In: Journal of Proteomics. 190, p. 12-20 9 p.

    Research output: Contribution to journalJournal articlepeer-review

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