Clare Louise Hawkins

Clare Louise Hawkins

Professor with special responsibilities


  1. β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia

    Karimi Galougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N. A., Hamilton, E. J., Hawkins, Clare Louise & Figtree, G. A., 19 Feb 2016, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 5, 2, e002824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants

    Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael Jonathan, Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In: Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages

    Love, D. T., Guo, C., Nikelshparg, E. I., Brazhe, N. A., Sosnovtseva, Olga & Hawkins, Clare Louise, 2020, In: Redox Biology. 36, 12 p., 101602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. The role of hypothiocyanous acid (HOSCN) in biological systems

    Hawkins, Clare Louise, Dec 2009, In: Free Radical Research. 43, 12, p. 1147-58 12 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  8. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity

    Yu, Y., Suryo Rahmanto, Y., Hawkins, Clare Louise & Richardson, D. R., Jun 2011, In: Molecular Pharmacology. 79, 6, p. 921-31 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael Jonathan, 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study

    Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In: Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The dys-regulation of anti-oxidant defense via an impairment of Nrf2 response in the pathology of Friedreich's ataxia: [Meeting Abstract]

    Chiang, S., Anzovino, A., Brown, B. E., Hawkins, Clare Louise, Richardson, D. R. & Huang, M. L. -., 2018, In: Free Radical Biology and Medicine. 120, p. S35-S35 OP-19 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In: FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In: Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In: Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Selenomethionine supplementation reduces lesion burden, improves vessel function and modulates the inflammatory response within the setting of atherosclerosis

    Zhang, Y., Cartland, S. P., Henriquez, R., Patel, S., Gammelgaard, Bente, Flouda, Konstantina, Hawkins, Clare Louise & Rayner, B. S., Jan 2020, In: Redox Biology. 29, 11 p., 101409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

    Guo, C., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage

    Flouda, Konstantina, Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 172, p. 633-651

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation

    Rayner, B. S., Zhang, Y., Brown, B. E., Reyes, L., Cogger, V. C. & Hawkins, Clare Louise, 2018, In: Free Radical Biology and Medicine. 129, p. 25-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Role of cyanate in the induction of vascular dysfunction during uremia: more than protein carbamylation?

    Hawkins, Clare Louise, Nov 2014, In: Kidney International. 86, 5, p. 875-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

    Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael Jonathan & Hawkins, Clare Louise, 2016, In: P L o S One. 11, 12, 16 p., e0168844.

    Research output: Contribution to journalJournal articleResearchpeer-review

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