Clare Louise Hawkins
Professor MSO
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › peer-review
Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations
Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 15 Apr 2010, In: Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.Research output: Contribution to journal › Journal article › peer-review
β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia
Karimi Galougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N. A., Hamilton, E. J., Hawkins, Clare Louise & Figtree, G. A., 19 Feb 2016, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 5, 2, e002824.Research output: Contribution to journal › Journal article › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael J., May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis
Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael J. & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.Research output: Contribution to journal › Journal article › peer-review
- Published
New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers
Jensen, M., Thorsen, N. W., Hallberg, L. A. E., Hägglund, Per Mårten & Hawkins, Clare Louise, 2023, In: Free Radical Biology and Medicine. 202, p. 97-109 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
ROLE OF EXTRACELLULAR TRAP RELEASE BY MACROPHAGES DURING THE DEVELOPMENT OF CHRONIC INFLAMMATION.
Jensen, M., Hägglund, Per Mårten, Zhang, Y., Rayner, B. & Hawkins, Clare Louise, 2021, In: Atherosclerosis. 331, p. E72-E72 PO51.Research output: Contribution to journal › Conference abstract in journal › peer-review
The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study
Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In: Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: P L o S One. 11, 12, 16 p., e0168844.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function
Indo, H. P., Hawkins, Clare Louise, Nakanishi, I., Matsumoto, K., Matsui, H., Suenaga, S., Davies, Michael J., St Clair, D. K., Ozawa, T. & Majima, H. J., 2017, Pharmacology of Mitochondria. Springer, Vol. 240. p. 439-456 18 p. (Handbook of Experimental Pharmacology, Vol. 240).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael J., Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In: Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Indo, H. P., Majima, H. J., Terada, M., Suenaga, S., Tomita, K., Yamada, S., Higashibata, A., Ishioka, N., Kanekura, T., Nonaka, I., Hawkins, Clare Louise, Davies, Michael J., Clair, D. K. S. & Mukai, C., 16 Dec 2016, In: Scientific Reports. 6, 10 p., 39015.Research output: Contribution to journal › Journal article › peer-review
- Published
Exposure to peroxynitrite impacts the ability of anastellin to modulate the structure of extracellular matrix
He, Jianfei, Chuang, Christine, Hawkins, Clare Louise, Davies, Michael J. & Hägglund, Per Mårten, 2023, In: Free Radical Biology and Medicine. 206, p. 83-93 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells
He, Jianfei, Steffen, Jonas Hyld, Thulstrup, Peter Waaben, Pedersen, J. N., Sauerland, Max Benjamin, Otzen, D. E., Hawkins, Clare Louise, Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2022, In: Scientific Reports. 12, 1, 15 p., 22051.Research output: Contribution to journal › Journal article › peer-review
- Published
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael J., Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael J., 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael J., 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 2 Jan 2002, In: FEBS Letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Hypochlorous acid-mediated modification of proteins and its consequences
Hawkins, Clare Louise, 2020, In: Essays in Biochemistry. 64, 1, p. 75-86Research output: Contribution to journal › Review › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael J., Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.Research output: Contribution to journal › Review › peer-review
- Published
Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael J., 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708Research output: Contribution to journal › Review › peer-review
ID: 173742266
Most downloads
-
252
downloads
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › peer-review
Published -
178
downloads
Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
Research output: Contribution to journal › Journal article › peer-review
Published -
153
downloads
Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Research output: Contribution to journal › Journal article › peer-review
Published