Clare Louise Hawkins

Clare Louise Hawkins

Professor with special responsibilities


  1. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hypochlorous acid-mediated modification of proteins and its consequences

    Hawkins, Clare Louise, 2020, In : Essays in Biochemistry. 64, 1, p. 75-86

    Research output: Contribution to journalReviewResearchpeer-review

  6. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Detection and characterisation of radicals in biological materials using EPR methodology

    Hawkins, Clare Louise & Davies, Michael Jonathan, Feb 2014, In : B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Detection, identification, and quantification of oxidative protein modifications

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Journal of Biological Chemistry. 294, 51, p. 19683-19708

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Protein carbamylation: a key driver of vascular calcification during chronic kidney disease

    Hawkins, Clare Louise, 2018, In : Kidney International. 94, 1, p. 12-14

    Research output: Contribution to journalComment/debateResearchpeer-review

  10. Role of cyanate in the induction of vascular dysfunction during uremia: more than protein carbamylation?

    Hawkins, Clare Louise, Nov 2014, In : Kidney International. 86, 5, p. 875-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. The role of hypothiocyanous acid (HOSCN) in biological systems

    Hawkins, Clare Louise, Dec 2009, In : Free Radical Research. 43, 12, p. 1147-58 12 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  12. Published

    A therapeutic role for selenoprotein T in reducing ischaemia/reperfusion injury in the heart?

    Hawkins, Clare Louise, 2018, In : Acta Physiologica. 223, 4, 3 p., e13106 .

    Research output: Contribution to journalEditorialResearchpeer-review

  13. Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)

    Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 531-42 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

    Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Jan 2011, In : Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

    Gamon, Luke Francis, Guo, Chaorui, He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In : Redox Biology. 36, 101586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

    Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In : Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The dys-regulation of anti-oxidant defense via an impairment of Nrf2 response in the pathology of Friedreich's ataxia: [Meeting Abstract]

    Chiang, S., Anzovino, A., Brown, B. E., Hawkins, Clare Louise, Richardson, D. R. & Huang, M. L. -., 2018, In : Free Radical Biology and Medicine. 120, p. S35-S35 OP-19 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage

    Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, Jul 2015, In : Free Radical Biology & Medicine. 84, p. 279-288 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes

    Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael Jonathan & Hawkins, Clare Louise, 2017, In : Redox Biology. 12, p. 872-882 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells

    Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 134, p. 526-536

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

    Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In : Scientific Reports. 13 p., 666.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 173742266