Clare Louise Hawkins

Clare Louise Hawkins

Professor with special responsibilities


  1. 2002
  2. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In : Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation

    Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Aug 2002, In : Biochemical Journal. 365, Pt 3, p. 605-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

    Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael Jonathan, Jul 2002, In : Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2003
  7. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, Apr 2003, In : Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In : Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Mar 2003, In : Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2004
  11. Published

    EPR spin trapping of protein radicals

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In : Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2005
  14. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael Jonathan, Oct 2005, In : Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael Jonathan, Nov 2005, In : Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation

    Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Oct 2005, In : Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2006
  18. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Feb 2006, In : Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2007
  20. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 28 Aug 2007, In : Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2008
  22. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael Jonathan, 15 Dec 2008, In : Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael Jonathan & Hawkins, Clare Louise, 1 Sep 2008, In : Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2008, In : Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2008, In : Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael Jonathan & Witting, P. K., 15 Sep 2008, In : Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2009
  29. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael Jonathan, 1 Jul 2009, In : Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. The role of hypothiocyanous acid (HOSCN) in biological systems

    Hawkins, Clare Louise, Dec 2009, In : Free Radical Research. 43, 12, p. 1147-58 12 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  31. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael Jonathan, 15 Apr 2009, In : Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael Jonathan, May 2009, In : Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2010
  34. The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study

    Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In : Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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