Christine Chuang

Christine Chuang

Assistant professor


  1. 2022
  2. Published

    Activation and Inhibition of Human Matrix Metalloproteinase-9 (MMP9) by HOCl, Myeloperoxidase and Chloramines

    Wang, Y., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., Aug 2022, In: Antioxidants. 11, 8, 22 p., 1616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage

    Xu, Shuqi, Chuang, Christine, Malle, E., Gamon, Luke Francis, Hawkins, Clare Louise & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 188, p. 162-174

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. 2021
  6. Published

    Chlorination and nitration of extracellular matrix by inflammatory myeloperoxidase-derived oxidants in the presence of nitrite

    Xu, Shuqi, Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 566 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hypoxia of human endothelial artery wall cells affects arterial extracellular matrix remodelling and contributes to atherosclerosis development

    Huang, S., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 563 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Phenotypic changes to vascular smooth muscle cells induced by extracellular matrix modification

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology & Medicine. 165, Suppl. 1, p. 36-37 NC38.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, 1 p., NC38.

    Research output: Contribution to journalConference abstract in journalResearch

  11. 2020
  12. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

    Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Scientific Reports. 13 p., 666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2019
  16. Published

    Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula

    Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 68-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 20, p. 496-513

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells

    Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 134, p. 526-536

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2018
  22. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., Oct 2018, In: Redox Biology. 19, p. 388-400

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

    Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]

    Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]

    Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Published

    Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]

    Cai, H., Chuang, Christine & Davies, Michael J., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A24-A24

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. 2017
  29. Published

    Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

    Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2016
  31. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2015
  33. A global map of hemispheric influenza vaccine recommendations based on local patterns of viral circulation

    Alonso, W. J., Chuang, Christine, Viboud, C., Richard, S. A., Schuck-paim, C., Simonsen, L., Mello, W. A. & Miller, M. A., 1 Dec 2015, In: Scientific Reports. 5, p. 1-6 6 p., 17214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2014
  36. Oxidation and modification of extracellular matrix and its role in disease

    Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling

    Baljinnyam, E., Umemura, M., Chuang, Christine, De Lorenzo, M. S., Iwatsubo, M., Chen, S., Goydos, J. S., Ishikawa, Y., Whitelock, J. M. & Iwatsubo, K., Jul 2014, In: Pigment Cell & Melanoma Research. 27, 4, p. 611-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

    Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael J., Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2012
  41. Published

    Not all lubricin isoforms are substituted with a glycosaminoglycan chain

    Lord, M. S., Estrella, R. P., Chuang, Christine, Youssef, P., Karlsson, N. G., Flannery, C. R. & Whitelock, J. M., 2012, In: Connective Tissue Research. 53, 2, p. 132-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2011
  43. Mechanisms and consequences of oxidative damage to extracellular matrix

    Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael J., Oct 2011, In: Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2010
  45. Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan

    Chuang, Christine, Lord, M. S., Melrose, J., Rees, M. D., Knox, S. M., Freeman, C., Iozzo, R. V. & Whitelock, J. M., 6 Jul 2010, In: Biochemistry. 49, 26, p. 5524-5532 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Enhanced tumor growth in the NaS1 sulfate transporter null mouse

    Dawson, P. A., Choyce, A., Chuang, Christine, Whitelock, J., Markovich, D. & Leggatt, G. R., Feb 2010, In: Cancer Science (Print). 101, 2, p. 369-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael J., Jan 2010, In: Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Similarity of recombinant human perlecan domain 1 by alternative expression systems bioactive heterogenous recombinant human perlecan D1

    Ellis, A. L., Pan, W., Yang, G., Jones, K., Chuang, Christine, Whitelock, J. M. & DeCarlo, A. A., 2010, In: B M C Biotechnology. 10, p. 66

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2008
  50. Published

    Recombinant heparan sulfate for use in tissue engineering applications

    Whitelock, J., Ma, J. L., Davies, N., Nielsen, N., Chuang, Christine, Rees, M., Iozzo, R. V., Knox, S. & Lord, M., 2008, In: Journal of Chemical Technology and Biotechnology. 83, 4, p. 496-504 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Tissue engineering of cartilages using biomatrices

    Melrose, J., Chuang, Christine & Whitelock, J., 2008, In: Journal of Chemical Technology and Biotechnology. 83, 4, p. 444-463 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 123540668