Christine Chuang

Christine Chuang

Assistant Professor


  1. Tissue engineering of cartilages using biomatrices

    Melrose, J., Chuang, Christine & Whitelock, J., 2008, In: Journal of Chemical Technology and Biotechnology. 83, 4, p. 444-463 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

    Lord, M. S., Chuang, Christine, Melrose, J., Davies, Michael J., Iozzo, R. V. & Whitelock, J. M., Apr 2014, In: Matrix Biology. 35, p. 112-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael J., Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican

    Jørgensen, Sara Marthedal, Lorentzen, Lasse Gøbel, Hammer, A., Hoefler, G., Malle, E., Chuang, Christine & Davies, Michael J., 2023, In: Redox Biology. 64, 19 p., 102794.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Similarity of recombinant human perlecan domain 1 by alternative expression systems bioactive heterogenous recombinant human perlecan D1

    Ellis, A. L., Pan, W., Yang, G., Jones, K., Chuang, Christine, Whitelock, J. M. & DeCarlo, A. A., 2010, In: B M C Biotechnology. 10, p. 66

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

    Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Recombinant heparan sulfate for use in tissue engineering applications

    Whitelock, J., Ma, J. L., Davies, N., Nielsen, N., Chuang, Christine, Rees, M., Iozzo, R. V., Knox, S. & Lord, M., 2008, In: Journal of Chemical Technology and Biotechnology. 83, 4, p. 496-504 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, 1 p., NC38.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Phenotypic changes to vascular smooth muscle cells induced by extracellular matrix modification

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology & Medicine. 165, Suppl. 1, p. 36-37 NC38.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published
  11. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

    Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Oxidation and modification of extracellular matrix and its role in disease

    Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Not all lubricin isoforms are substituted with a glycosaminoglycan chain

    Lord, M. S., Estrella, R. P., Chuang, Christine, Youssef, P., Karlsson, N. G., Flannery, C. R. & Whitelock, J. M., 2012, In: Connective Tissue Research. 53, 2, p. 132-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael J., Jan 2010, In: Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN)

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Redox Biology. 36, 13 p., 101641.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival

    Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]

    Cai, H., Chuang, Christine & Davies, Michael J., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A24-A24

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Mechanisms and consequences of oxidative damage to extracellular matrix

    Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael J., Oct 2011, In: Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage

    Xu, Shuqi, Chuang, Christine, Malle, E., Gamon, Luke Francis, Hawkins, Clare Louise & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 188, p. 162-174

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

    Lorentzen, Lasse Gøbel, Chuang, Christine, Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 24, UNSP 101226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Hypoxia of human endothelial artery wall cells affects arterial extracellular matrix remodelling and contributes to atherosclerosis development

    Huang, S., Chuang, Christine & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 563 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

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