Carolyn F. Deacon
Carolyn F. Deacon

Associate Professor


  1. 2005
  2. Published

    The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

    Research output: Contribution to journalJournal articleResearch

  3. Published

    Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In : J. Clin. Endocrinol. Metab.. 90, p. 4888-4894

    Research output: Contribution to journalJournal articleResearch

  4. Published

    What do we know about the secretion and degradation of incretin hormones?

    Deacon, Carolyn F., 2005, In : Regulatory Peptides. 128, 2, p. 117-24 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2004
  6. Published

    Circulation and degradation of GIP and GLP-1

    Deacon, Carolyn F., 2004, In : Hormone and Metabolic Research. 36, p. 761-765

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.

    Holst, Jens Juul & Deacon, Carolyn F., 2004, In : Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?

    Deacon, Carolyn F., Ahrén, B. & Holst, Jens Juul, 2004, In : Expert Opinion on Investigational Drugs. 13, 9, p. 1091-102 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.

    Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In : American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

    Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In : Regulatory Peptides. 122, 3, p. 209-17 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.

    Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In : Diabetes. 53, 3, p. 654-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

    Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In : Diabetes. 53 Suppl 3, p. S220-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice.

    Rolin, B., Deacon, Carolyn F., Carr, R. D. & Ahrén, B., 2004, In : European Journal of Pharmacology. 494, 2-3, p. 283-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Therapeutic strategies based on glucagon-like peptide 1.

    Deacon, Carolyn F., 2004, In : Diabetes. 53, 9, p. 2181-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2003
  16. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In : Diabetologia. 46, 6, p. 798-801 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Differential regional metabolism of glucagon in anesthetized pigs.

    Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In : American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics.

    Sturis, J., Gotfredsen, C. F., Rømer, J., Rolin, B., Ribel, U., Brand, C. L., Wilken, M., Wassermann, K., Deacon, Carolyn F., Carr, R. D. & Knudsen, L. B., 2003, In : British Journal of Pharmacology. 140, 1, p. 123-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

    Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In : Diabetologia. 46, p. 798-801

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

    Ugleholdt, R., Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In : Endocrinology. 145, 3, p. 1349-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In : Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

    Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In : Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In : Regulatory Peptides. 113, 1-3, p. 95-100 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass.

    Larsen, M. O., Rolin, B., Ribel, U., Wilken, M., Deacon, Carolyn F., Svendsen, O., Gotfredsen, C. F. & Carr, R. D., 2003, In : Experimental Diabesity Research. 4, 2, p. 93-105 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2002
  26. Published

    Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs

    Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In : Journal of Endocrinology. 172, 2, p. 355-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.

    Deacon, Carolyn F. & Holst, Jens Juul, 2002, In : Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.

    Deacon, Carolyn F., Plamboeck, A., Møller, Søren & Holst, Jens Juul, 2002, In : American Journal of Physiology: Endocrinology and Metabolism. 282, 4, p. E873-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs.

    Ribel, U., Larsen, M. O., Rolin, B., Carr, R. D., Wilken, M., Sturis, J., Westergaard, L., Deacon, Carolyn F. & Knudsen, L. B., 2002, In : European Journal of Pharmacology. 451, 2, p. 217-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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