Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor

Member of:

    ORCID: 0000-0003-2611-5642

    Publication year:
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    51 - 100 out of 236Page size: 50
    1. 2005
    2. Published

      The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

      Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

      Research output: Contribution to journal › Journal article

    3. Published

      Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes

      Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 4888-4894

      Research output: Contribution to journal › Journal article

    4. Published

      Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes

      Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    5. Published

      Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes

      Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881

      Research output: Contribution to journal › Journal article

    6. Published

      Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig

      Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., Sep 2005, In: Diabetologia. 48, 9, p. 1882-90 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    7. Published

      Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig

      Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890

      Research output: Contribution to journal › Journal article › peer-review

    8. Published

      Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight

      Schou, J. H., Pilgaard, K., Vilsbøll, Tina, Jensen, C. B., Deacon, Carolyn F., Holst, Jens Juul, Vølund, A., Madsbad, Sten & Vaag, Allan, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4912-19 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    9. 2006
    10. Published

      GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.

      Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75

      Research output: Contribution to journal › Journal article › peer-review

    11. Published

      Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice.

      Gunnarsson, P. T., Winzell, M. S., Deacon, Carolyn F., Larsen, M. O., Jelic, K., Carr, R. D. & Ahrén, B., 2006, In: Endocrinology. 147, 7, p. 3173-80 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    12. Published

      Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

      Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    13. Published

      Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy

      Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    14. Published

      Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

      Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q., Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    15. Published

      Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes

      Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Avances en Diabetologia. 22, 2, p. 115-125 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    16. Published

      Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.

      Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    17. Published

      The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.

      Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23

      Research output: Contribution to journal › Journal article › peer-review

    18. Published

      Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake

      Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    19. Published

      Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

      Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    20. Published

      Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

      Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    21. Published

      The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

      Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    22. Published

      The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

      Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    23. Published

      The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

      Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    24. 2007
    25. Published

      Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

      Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    26. Published

      The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

      Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    27. Published

      Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes.

      Deacon, Carolyn F., 2007, In: Expert Opinion on Investigational Drugs. 16, 4, p. 533-45 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    28. Published

      Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors.

      Deacon, Carolyn F., 2007, In: Diabetes, Obesity and Metabolism. 9 Suppl 1, p. 23-31 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    29. Published

      Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

      He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    30. Published

      Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

      He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

      Research output: Contribution to journal › Journal article › peer-review

    31. Published

      New horizons in diabetes therapy

      Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    32. Published

      Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects

      Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    33. Published

      Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

      Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

      Research output: Contribution to journal › Journal article › peer-review

    34. Published

      The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose

      Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    35. 2008
    36. Published

      KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

      Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    37. Published

      Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

      Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

      Research output: Contribution to journal › Journal article › peer-review

    38. Published

      Incretin and islet hormonal responses to fat and protein ingestion in healthy men.

      Carr, R. D., Larsen, M. O., Winzell, M. S., Jelic, K., Lindgren, O., Deacon, Carolyn F. & Ahrén, B., 2008, In: American Journal of Physiology: Endocrinology and Metabolism. 295, 4, p. E779-84

      Research output: Contribution to journal › Journal article › peer-review

    39. Published

      Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

      Deacon, Carolyn F., 2008, In: Current Opinion in Investigational Drugs. 9, 4, p. 402-13 11 p.

      Research output: Contribution to journal › Journal article › peer-review

    40. Published

      DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

      Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    41. Published

      Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

      Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

      Research output: Contribution to journal › Journal article › peer-review

    42. Published

      Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes

      Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.

      Research output: Contribution to journal › Journal article › peer-review

    43. Published

      Glucagon-like peptide-1, glucose homeostasis and diabetes.

      Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    44. Published

      The incretin system and its role in type 2 diabetes mellitus

      Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    45. Published

      Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

      Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

      Research output: Contribution to journal › Journal article › peer-review

    46. Published

      Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

      Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    47. Published

      Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance.

      Rosenstock, J., Foley, J. E., Rendell, M., Landin-Olsson, M., Holst, Jens Juul, Deacon, Carolyn F., Rochotte, E. & Baron, M. A., 2008, In: Diabetes Care. 31, 1, p. 30-5 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    48. Published

      Overnight hypoxic exposure and glucagon-like peptide-1 and leptin levels in humans.

      Snyder, E. M., Carr, R. D., Deacon, Carolyn F. & Johnson, B. D., 2008, In: Applied Physiology, Nutrition and Metabolism. 33, 5, p. 929-35 6 p.

      Research output: Contribution to journal › Journal article › peer-review

    49. Published

      The effect of dipeptidyl peptidase 4 inhibition on gastric volume, satiation and enteroendocrine secretion in Type 2 diabetes: a double blind, placebo-controlled crossover study.

      Vella, A., Bock, G., Giesler, P. D., Burton, D. B., Serra, D. B., Saylan, M. L., Deacon, Carolyn F., Foley, J. E., Rizza, R. A. & Camilleri, M., 2008, In: Clinical Endocrinology.

      Research output: Contribution to journal › Journal article › peer-review

    50. 2009
    51. Published

      Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

      Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

      Research output: Contribution to journal › Conference abstract in journal

    52. Published

      KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

      Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

      Research output: Contribution to journal › Journal article › peer-review

    53. Published

      Immunoassays for the incretin hormones GIP and GLP-1

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 425-32 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    54. Published

      Potential of liraglutide in the treatment of patients with type 2 diabetes

      Deacon, Carolyn F., 2009, In: Vascular Health and Risk Management (Online). 5, 1, p. 199-211 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    55. Published

      Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Advances in Therapy. 26, 5, p. 488-99 11 p.

      Research output: Contribution to journal › Journal article › peer-review

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