Bolette Hartmann

Bolette Hartmann

Associate Professor


  1. Published

    The role of endogenous GIP and GLP-1 in postprandial bone homeostasis

    Helsted, Mads Marstrand, Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, F. K., 2020, In: Bone. 140, 7 p., 115553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial

    Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, F. K., Jul 2020, In: Diabetologia. 63, p. 1285-1298

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes

    Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, F. K., 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, J., Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, F. K., Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

    Modvig, I. M., Andersen, Daniel Bjørklund, Grunddal, K. V., Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery

    Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients

    Thomsen, Mads Norvin, Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, Arne, Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published

    Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents with Obesity

    Higgins, V., Asgari, S., Hamilton, J. K., Wolska, A., Remaley, A. T., Hartmann, Bolette, Holst, Jens Juul & Adeli, K., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. 1228-1241

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice

    Hunt, J. E., Billeschou, Anna, Windeløv, J. A., Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Oral D/L-3-Hydroxybutyrate Stimulates Cholecystokinin and Insulin Secretion and Slows Gastric Emptying in Healthy Males

    Rittig, N., Svart, M., Thomsen, H. H., Vestergaard, E. T., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Johannsen, M., Møller, N. & Jessen, N., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 10, 9 p., dgaa483.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis

    Gether, L., Thyssen, J. P., Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, F. K., 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes

    Svane, M. S., Johannesen, H. H., Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

    Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, F. K., 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Lixisenatide in type 1 diabetes: A randomised control trial of the effect of lixisenatide on post-meal glucose excursions and glucagon in type 1 diabetes patients

    Ballav, C., Dhere, A., Kennedy, I., Agbaje, O. F., White, S., Franklin, R., Hartmann, Bolette, Holst, Jens Juul, Holman, R. R. & Owen, K. R., 2020, In: Endocrinology, Diabetes and Metabolism. 3, 3, 9 p., e00130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

    Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, Bolette, Clausen, T. R., Veedfald, Simon, Kristiansen, V. B., Rehfeld, Jens Frederik, Hansen, Harald S., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma

    Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, Jens, 2020, In: Physiological Reports. 8, 15, 11 p., e14519.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    In vivo positron emission tomography imaging of decreased parasympathetic innervation in the gut of vagotomized patients

    Fedorova, T. D., Knudsen, K., Hartmann, Bolette, Holst, Jens Juul, Mortensen, F. V., Krogh, K. & Borghammer, P., 2020, In: Neurogastroenterology and Motility. 32, 3, 8 p., 13759.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans

    Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, F. K., Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucagon-Like Peptide 2 Inhibits Postprandial Gallbladder Emptying in Man: A Randomized, Double-Blinded, Crossover Study

    Hansen, Nina Lerberg, Bronden, A., Nexoe-Larsen, C. C., Christensen, A. S., Sonne, D. P., Rehfeld, Jens Frederik, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul & Knop, F. K., 2020, In: Clinical and Translational Gastroenterology. 11, 12, 9 p., e00257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2

    Gasbjerg, Lærke Smidt, Hartmann, Bolette, Christensen, Mikkel Bring, Lanng, A. R., Vilsbøll, Tina, Jørgensen, Niklas Rye, Holst, Jens Juul, Rosenkilde, Mette & Knop, F. K., 2020, In: Bone. 130, 6 p., 115079 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    GIP infusion in patients with type 1 diabetes seems to attenuate post-prandial glucose excursions after prandial insulin over-dose and physical activity

    Hoe, B., Heimburger, S. M. N., Gasbjerg, L. S., Lanng, A. R., Lynggaard, M. B., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A., Engberg, S., Dejgaard, T. F., Christensen, Mikkel Bring & Knop, F. K., 2020, In: Diabetologia. 63, Suppl. 1, p. S117 1 p., 232.

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    GIP and the gut-bone axis – Physiological, pathophysiological and potential therapeutic implications

    Stensen, S., Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Christensen, Mikkel Bring & Knop, F. K., 2020, In: Peptides. 125, 7 p., 170197.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals

    Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Sparre-Ulrich, A. H., Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, F. K., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e725-e738 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice

    Gobron, B., Bouvard, B., Vyavahare, S., Blom, L. V. V., Pedersen, K. K., Windelov, J. A., Boer, G. A., Harada, N., Zhang, S., Shimazu-Kuwahara, S., Wice, B., Inagaki, N., Legrand, E., Flatt, P. R., Chappard, D., Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette, Irwin, N. & Mabilleau, G., 2020, In: Journal of Bone and Mineral Research. 35, 7, p. 1363-1374 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

    Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, Sarina, Smit, F. X., Hartmann, Bolette, Bräuner-Osborne, Hans & Rosenkilde, Mette, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 122-132

    Research output: Contribution to journalJournal articleResearchpeer-review

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