Bolette Hartmann
Associate Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2016
- Published
Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion
Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.Research output: Contribution to journal › Journal article › peer-review
- Published
Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs
Østergaard, M. V., Shen, René Liang, Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, Dennis Sandris, Hartmann, Bolette, Bering, Stine Brandt, Schmidt, M. & Sangild, Per Torp, 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-566 15 p.Research output: Contribution to journal › Journal article › peer-review
- 2015
- Published
Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › peer-review
- Published
Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists
Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Important species differences regarding lymph contribution to gut hormone responses
Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.
Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study
Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx
Kuhre, Rune Ehrenreich, Bechmann, L. E., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 21 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, p. E1123–E1130 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine
Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.Research output: Contribution to journal › Journal article › peer-review
- Published
Stability of glucagon-like peptide-1 and glucagon in human plasma
Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs
Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure
Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass
Guimarães, M., Rodrigues, P., Pereira, S. S., Nora, M., Gonçalves, G., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Holst, Jens Juul & Monteiro, M. P., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-5 5 p., 150049.Research output: Contribution to journal › Journal article › peer-review
- Published
Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides
Challis, B. G., Albrechtsen, Nicolai Jacob Wewer, Bansiya, V., Burling, K., Barker, P., Hartmann, Bolette, Gribble, F., O'Rahilly, S., Holst, Jens Juul & Simpson, H. L., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-7 7 p., 150105.Research output: Contribution to journal › Journal article › peer-review
- Published
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, J., Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept
Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › peer-review
- 2014
- Published
Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model
Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?
Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition
Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans
Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The incretin effect does not differ in trained and untrained, young, healthy men
Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs
Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glucagon-like peptide 2 treatment may improve intestinal adaptation during weaning
Thymann, Thomas, Le Huërou-Luron, I., Petersen, Y. M., Hedemann, M. S., Elinf, J., Jensen, B. B., Holst, Jens Juul, Hartmann, Bolette & Sangild, Per Torp, 2014, In: Journal of Animal Science. 92, 5, p. 2070-2079 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.Research output: Contribution to journal › Journal article › peer-review
- 2013
- Published
Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
Lund, M. T., Taudorf, L., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 1 Nov 2013, In: European Journal of Applied Physiology. 113, 11, p. 2737-47 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients
Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In: Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients
Naimi, R. M., Madsen, K. B., Askov-Hansen, C., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 47-53 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study
Madsen, K. B., Askov-Hansen, C., Naimi, R. M., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 30-9 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In: International Journal of Obesity. 37, p. 1452-1459 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure
Askov-Hansen, C., Jeppesen, Palle Bekker, Lund, P., Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 10 Feb 2013, In: Regulatory Peptides. 181, p. 4-8 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates
Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, Stine Brandt, Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.Research output: Contribution to journal › Journal article › peer-review
- 2012
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
- Published
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs
Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine
Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome
Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In: European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.Research output: Contribution to journal › Journal article › peer-review
ID: 16847940
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
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