Astrid Sissel Jørgensen

Astrid Sissel Jørgensen

External, Ph.d Student


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  1. 2023
  2. Published

    Identification of a Salt Bridge That Is Functionally Important for Chemokine Receptor CXCR1 but not CXCR2

    Våbenø, J., Oliva-Santiago, M., Jørgensen, Astrid Sissel, Karlshøj, S. & Rosenkilde, Mette, 2023, In: ACS Pharmacology and Translational Science. 6, 8, p. 1120-1128 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2022
  5. Published

    Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation

    Jensen, Sune K. , Pærregaard, S. I., Brandum, E. P., Jørgensen, Astrid Sissel, Hjortø, Gertrud Malene & Jensen, Benjamin Anderschou Holbech, 25 Jan 2022, In: Gastroenterology Report. 10, p. 1-15 goac008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails

    Brandum, E. P., Jørgensen, Astrid Sissel, Calvo, M. B., Spiess, Katja, Peterson, F. C., Yang, Zhang, Volkman, B. F., Veldkamp, C. T., Rosenkilde, Mette, Goth, C. K. & Hjortø, Gertrud Malene, 2022, In: International Journal of Molecular Sciences. 23, 3, 20 p., 1397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2021
  8. Published

    Biased action of the CXCR4-targeting drug plerixafor is essential for its superior hematopoietic stem cell mobilization

    Jørgensen, Astrid Sissel, Daugvilaite, V., De Filippo, K., Berg, Christian, Mavri, M., Benned-Jensen, T., Juzenaite, G., Hjortø, Gertrud Malene, Rankin, S., Vabeno, J. & Rosenkilde, Mette, 2021, In: Communications Biology . 4, 1, 12 p., 569.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

    Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2019
  11. Published

    Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

    Jørgensen, Astrid Sissel, Larsen, Olav, Uetz-von Allmen, E., Lückmann, Michael, Legler, D. F., Frimurer, Thomas Michael, Veldkamp, C. T., Hjortø, Gertrud Malene & Rosenkilde, Mette, 2019, In: Frontiers in Immunology. 10, 14 p., 2156.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2018
  13. Published

    Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4

    Berg, Christian, Daugvilaite, V., Steen, A., Jørgensen, Astrid Sissel, Våbenø, J. & Rosenkilde, Mette, 20 Apr 2018, In: ACS chemical biology. 13, 4, p. 881-886 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Biased signaling of G protein-coupled receptors: rom a chemokine receptor CCR7 perspective

    Jørgensen, Astrid Sissel, Rosenkilde, Mette & Hjortø, Gertrud Malene, Mar 2018, In: General and Comparative Endocrinology. 258, SI, p. 4-14

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    CCL19 with CCL21-tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells

    Jørgensen, Astrid Sissel, Adogamhe, P. E., Laufer, J. M., Legler, D. F., Veldkamp, C. T., Rosenkilde, M. M. & Hjortø, Gertrud Malene, 2018, In: Journal of Leukocyte Biology. 104, 2, p. 401-411

    Research output: Contribution to journal › Journal article › Research › peer-review

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