Alicia Lundby
Affiliated Associate Professor, Professor with special responsibilities, Professor MSO
Mann Group
Blegdamsvej 3B
2200 København N
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
Member of:
- Published
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, Mads, Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.Research output: Contribution to journal › Journal article › peer-review
Effect of voltage sensitive fluorescent proteins on neuronal excitability
Akemann, W., Lundby, Alicia, Mutoh, H. & Knöpfel, T., 2009, In: Biophysical Journal. 96, 10, p. 3959-76 17 p.Research output: Contribution to journal › Journal article › peer-review
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Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking
Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In: American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.Research output: Contribution to journal › Journal article › peer-review
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M. & 31 others, , 22 Jun 2014, In: Nature Genetics. 46, 8, p. 826-838 13 p.Research output: Contribution to journal › Journal article › peer-review
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Proteome-wide profiling and mapping of post translational modifications in human hearts
Bagwan, N., El Ali, Henrik H. & Lundby, Alicia, 2021, In: Scientific Reports. 11, 1, 10 p., 2184.Research output: Contribution to journal › Journal article › peer-review
- Published
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle
Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.Research output: Contribution to journal › Journal article › peer-review
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Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia
D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Da Costa Martins, P. A., Kitmitto, A., Wisløff, U., Cartwright, E. J., Monfredi, O. & 5 others, , Oct 2017, In: Circulation Research. 121, 9, p. 1058-1068 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › peer-review
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Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › peer-review
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Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)
Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo
Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.Research output: Contribution to journal › Journal article › peer-review
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Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice
Kim, J., Perez-Hernandez, M., Alvarado, F. J., Maurya, S. R., Montnach, J., Yin, Y., Zhang, M., Lin, X., Vasquez, C., Heguy, A., Liang, F., Woo, S., Morley, G. E., Rothenberg, E., Lundby, Alicia, Valdivia, H. H., Cerrone, M. & Delmar, M., 2019, In: Circulation. 140, 12, p. 1015-1030Research output: Contribution to journal › Journal article › peer-review
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Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation
Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144Research output: Contribution to journal › Journal article › peer-review
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Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › peer-review
- Published
Phosphoproteomics taken to heart
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In: Cell Cycle. 12, 17, p. 2707-2708 2 p.Research output: Contribution to journal › Editorial › peer-review
- Published
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, , 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.Research output: Contribution to journal › Journal article › peer-review
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › peer-review
- Published
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.Research output: Contribution to journal › Journal article › peer-review
- Published
Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements
Lundby, Alicia, Mutoh, H., Dimitrov, D., Akemann, W. & Knöpfel, T., 2008, In: PLoS ONE. 3, 6, p. e2514Research output: Contribution to journal › Journal article › peer-review
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Molecular template for a voltage sensor in a novel K+ channel II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel
Lundby, Alicia, Santos, J., Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 293-300Research output: Contribution to journal › Journal article › peer-review
- Published
In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling
Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP
Lundby, Alicia, Akemann, W. & Knöpfel, T., 6 Aug 2010, In: European Biophysics Journal. 39, 12, p. 1625-1635 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Structural basis for KV7.1/KCNEx interactions in the IKs channel complex
Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In: Heart Rhythm. 7, 5, p. 708-713Research output: Contribution to journal › Journal article › peer-review
- Published
GeLCMS for in-depth protein characterization and advanced analysis of proteomes
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
ID: 10426
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456
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › peer-review
Published -
409
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › peer-review
Published -
373
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › peer-review
Published