Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. / Dose, Nynne; Michelsen, Marie Mide; Mygind, Naja Dam; Pena, Adam; Ellervik, Christina; Hansen, Peter R; Kanters, Jørgen K; Prescott, Eva; Kastrup, Jens; Steering Committee of the iPOWER study; Gustafsson, Ida; Hansen, Henrik Steen.

I: Journal of Electrocardiology, Bind 51, Nr. 1, 01.2018, s. 15-20.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Dose, N, Michelsen, MM, Mygind, ND, Pena, A, Ellervik, C, Hansen, PR, Kanters, JK, Prescott, E, Kastrup, J, Steering Committee of the iPOWER study, Gustafsson, I & Hansen, HS 2018, 'Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction', Journal of Electrocardiology, bind 51, nr. 1, s. 15-20. https://doi.org/10.1016/j.jelectrocard.2017.08.017

APA

Dose, N., Michelsen, M. M., Mygind, N. D., Pena, A., Ellervik, C., Hansen, P. R., Kanters, J. K., Prescott, E., Kastrup, J., Steering Committee of the iPOWER study, Gustafsson, I., & Hansen, H. S. (2018). Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. Journal of Electrocardiology, 51(1), 15-20. https://doi.org/10.1016/j.jelectrocard.2017.08.017

Vancouver

Dose N, Michelsen MM, Mygind ND, Pena A, Ellervik C, Hansen PR o.a. Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. Journal of Electrocardiology. 2018 jan.;51(1):15-20. https://doi.org/10.1016/j.jelectrocard.2017.08.017

Author

Dose, Nynne ; Michelsen, Marie Mide ; Mygind, Naja Dam ; Pena, Adam ; Ellervik, Christina ; Hansen, Peter R ; Kanters, Jørgen K ; Prescott, Eva ; Kastrup, Jens ; Steering Committee of the iPOWER study ; Gustafsson, Ida ; Hansen, Henrik Steen. / Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction. I: Journal of Electrocardiology. 2018 ; Bind 51, Nr. 1. s. 15-20.

Bibtex

@article{7e172faa49dc47f18e66579ede16e92f,
title = "Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction",
abstract = "OBJECTIVES: CMD could be the explanation of angina pectoris with no obstructive CAD and may cause ventricular repolarization changes. We compared T-wave morphology and QTc interval in women with angina pectoris with a control group as well as the associations with CMD.METHODS: Women with angina pectoris and no obstructive coronary artery disease (n=138) and age-matched controls were compared in regard to QTc interval and morphology combination score (MCS) based on T-wave asymmetry, flatness and presence of T-wave notch. CMD was assessed as a coronary flow velocity reserve (CFVR) by transthoracic echocardiography.RESULTS: Women with angina pectoris had significantly longer QTc intervals (429±20ms) and increased MCS (IQR) (0.73 [0.64-0.80]) compared with the controls (419±20ms) and (0.63 [(0.53-0.73]), respectively (both p<0.001). CFVR was associated with longer QTc interval (p=0.02), but the association was attenuated after multivariable adjustment (p=0.08).CONCLUSION: This study suggests that women with angina pectoris have alterations in T-wave morphology as well as longer QTc interval compared with a reference population. CMD might be an explanation.",
keywords = "Journal Article",
author = "Nynne Dose and Michelsen, {Marie Mide} and Mygind, {Naja Dam} and Adam Pena and Christina Ellervik and Hansen, {Peter R} and Kanters, {J{\o}rgen K} and Eva Prescott and Jens Kastrup and {Steering Committee of the iPOWER study} and Ida Gustafsson and Hansen, {Henrik Steen}",
note = "Copyright {\textcopyright} 2017 Elsevier Inc. All rights reserved.",
year = "2018",
month = jan,
doi = "10.1016/j.jelectrocard.2017.08.017",
language = "English",
volume = "51",
pages = "15--20",
journal = "Journal of Electrocardiology",
issn = "0022-0736",
publisher = "Churchill Livingstone",
number = "1",

}

RIS

TY - JOUR

T1 - Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction

AU - Dose, Nynne

AU - Michelsen, Marie Mide

AU - Mygind, Naja Dam

AU - Pena, Adam

AU - Ellervik, Christina

AU - Hansen, Peter R

AU - Kanters, Jørgen K

AU - Prescott, Eva

AU - Kastrup, Jens

AU - Steering Committee of the iPOWER study

AU - Gustafsson, Ida

AU - Hansen, Henrik Steen

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2018/1

Y1 - 2018/1

N2 - OBJECTIVES: CMD could be the explanation of angina pectoris with no obstructive CAD and may cause ventricular repolarization changes. We compared T-wave morphology and QTc interval in women with angina pectoris with a control group as well as the associations with CMD.METHODS: Women with angina pectoris and no obstructive coronary artery disease (n=138) and age-matched controls were compared in regard to QTc interval and morphology combination score (MCS) based on T-wave asymmetry, flatness and presence of T-wave notch. CMD was assessed as a coronary flow velocity reserve (CFVR) by transthoracic echocardiography.RESULTS: Women with angina pectoris had significantly longer QTc intervals (429±20ms) and increased MCS (IQR) (0.73 [0.64-0.80]) compared with the controls (419±20ms) and (0.63 [(0.53-0.73]), respectively (both p<0.001). CFVR was associated with longer QTc interval (p=0.02), but the association was attenuated after multivariable adjustment (p=0.08).CONCLUSION: This study suggests that women with angina pectoris have alterations in T-wave morphology as well as longer QTc interval compared with a reference population. CMD might be an explanation.

AB - OBJECTIVES: CMD could be the explanation of angina pectoris with no obstructive CAD and may cause ventricular repolarization changes. We compared T-wave morphology and QTc interval in women with angina pectoris with a control group as well as the associations with CMD.METHODS: Women with angina pectoris and no obstructive coronary artery disease (n=138) and age-matched controls were compared in regard to QTc interval and morphology combination score (MCS) based on T-wave asymmetry, flatness and presence of T-wave notch. CMD was assessed as a coronary flow velocity reserve (CFVR) by transthoracic echocardiography.RESULTS: Women with angina pectoris had significantly longer QTc intervals (429±20ms) and increased MCS (IQR) (0.73 [0.64-0.80]) compared with the controls (419±20ms) and (0.63 [(0.53-0.73]), respectively (both p<0.001). CFVR was associated with longer QTc interval (p=0.02), but the association was attenuated after multivariable adjustment (p=0.08).CONCLUSION: This study suggests that women with angina pectoris have alterations in T-wave morphology as well as longer QTc interval compared with a reference population. CMD might be an explanation.

KW - Journal Article

U2 - 10.1016/j.jelectrocard.2017.08.017

DO - 10.1016/j.jelectrocard.2017.08.017

M3 - Journal article

C2 - 28939174

VL - 51

SP - 15

EP - 20

JO - Journal of Electrocardiology

JF - Journal of Electrocardiology

SN - 0022-0736

IS - 1

ER -

ID: 189664709