Type 2 diabetes and psoriasis: links and risks
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Type 2 diabetes and psoriasis : links and risks. / Holm, Jesper Gronlund; Thomsen, Simon Francis.
I: Psoriasis: Targets and Therapy, Bind 9, 2019, s. 1-6.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Type 2 diabetes and psoriasis
T2 - links and risks
AU - Holm, Jesper Gronlund
AU - Thomsen, Simon Francis
PY - 2019
Y1 - 2019
N2 - Psoriasis (PsO) is one of the most common chronic inflammatory skin diseases with a world prevalence of 2%-4%. The increasing knowledge of the mechanisms driving PsO has raised focus on existing links to metabolic syndrome and type 2 diabetes (T2D). We reviewed the existing literature of the prevalence and risk of T2D in patients with PsO. The studies reviewed were mainly large retrospective cohort and case-control studies, showing an increased prevalence of T2D in PsO patients compared to controls, particularly in late onset (type 2) PsO. T2D prevalence did not correlate to patient age or severity of PsO in the reviewed studies. Conclusively, T2D was found to be more prevalent in patients with PsO compared to the background population. Several mechanisms involved in lipid transportation seem to be upregulated in PsO patients. Physicians play a key role concerning information about known comorbidity and promotion of early prophylaxis in patients with PsO.
AB - Psoriasis (PsO) is one of the most common chronic inflammatory skin diseases with a world prevalence of 2%-4%. The increasing knowledge of the mechanisms driving PsO has raised focus on existing links to metabolic syndrome and type 2 diabetes (T2D). We reviewed the existing literature of the prevalence and risk of T2D in patients with PsO. The studies reviewed were mainly large retrospective cohort and case-control studies, showing an increased prevalence of T2D in PsO patients compared to controls, particularly in late onset (type 2) PsO. T2D prevalence did not correlate to patient age or severity of PsO in the reviewed studies. Conclusively, T2D was found to be more prevalent in patients with PsO compared to the background population. Several mechanisms involved in lipid transportation seem to be upregulated in PsO patients. Physicians play a key role concerning information about known comorbidity and promotion of early prophylaxis in patients with PsO.
KW - psoriasis
KW - type 2 diabetes
KW - association
KW - risk
KW - link
U2 - 10.2147/PTT.S159163
DO - 10.2147/PTT.S159163
M3 - Review
C2 - 30697518
VL - 9
SP - 1
EP - 6
JO - Psoriasis: Targets and Therapy
JF - Psoriasis: Targets and Therapy
SN - 2230-326X
ER -
ID: 230143590