Training and natural immunity: effects of diets rich in fat or carbohydrate

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Standard

Training and natural immunity : effects of diets rich in fat or carbohydrate. / Pedersen, Bente Klarlund; Helge, Jørn Wulff; Richter, Erik; Rohde, Thomas; Kiens, Bente.

I: European Journal of Applied Physiology, Bind 82, Nr. 1-2, 01.05.2000, s. 98-102.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Pedersen, BK, Helge, JW, Richter, E, Rohde, T & Kiens, B 2000, 'Training and natural immunity: effects of diets rich in fat or carbohydrate', European Journal of Applied Physiology, bind 82, nr. 1-2, s. 98-102. https://doi.org/10.1007/s004210050657

APA

Pedersen, B. K., Helge, J. W., Richter, E., Rohde, T., & Kiens, B. (2000). Training and natural immunity: effects of diets rich in fat or carbohydrate. European Journal of Applied Physiology, 82(1-2), 98-102. https://doi.org/10.1007/s004210050657

Vancouver

Pedersen BK, Helge JW, Richter E, Rohde T, Kiens B. Training and natural immunity: effects of diets rich in fat or carbohydrate. European Journal of Applied Physiology. 2000 maj 1;82(1-2):98-102. https://doi.org/10.1007/s004210050657

Author

Pedersen, Bente Klarlund ; Helge, Jørn Wulff ; Richter, Erik ; Rohde, Thomas ; Kiens, Bente. / Training and natural immunity : effects of diets rich in fat or carbohydrate. I: European Journal of Applied Physiology. 2000 ; Bind 82, Nr. 1-2. s. 98-102.

Bibtex

@article{c776de4c484c4b978047257b69e6f130,
title = "Training and natural immunity: effects of diets rich in fat or carbohydrate",
abstract = "The purpose of the study was to investigate whether a carbohydrate-rich versus fat-rich diet influenced the effect of training on the immune system. Ten untrained young men ingested a carbohydrate-rich diet [65 energy percent (E{\%}) carbohydrate] and ten subjects a fat-rich diet (62E{\%} fat) while endurance training was performed 3-4 times a week for 7 weeks. Maximal oxygen uptake increased by 11{\%} in both groups. Blood samples for immune monitoring were collected before and at the end of the study. Blood samples were also collected, in parallel, from 20 age-matched subjects, and data from these subjects were used to eliminate day-to-day variation in the immunological tests. Independently of diet, training increased the percentage of CD3-CD16+ CD56+ natural killer (NK) cells from [mean (SEM)] 14 (1) {\%} to 20 (3) {\%} (P = 0.05), whereas the NK-cell activity, either unstimulated or stimulated with interleukin (IL)-2 or interferon (IFN)-alpha, did not change. Furthermore, training did not influence the percentages of CD3+, CD4+, CD8+, CD19+ or CD14+ cells. However, when the two diet groups were compared, it was found that the NK-cell activity had increased in the group on the carbohydrate-rich diet [from 16 (3){\%} to 27 (2){\%}] and decreased in the group on the fat-rich diet [from 26 (2){\%} to 20 (4){\%}] in response to training. The effect of training on unstimulated NK-cell activity was significantly different between the groups (P = 0.007). These data indicate that diet manipulation during training may influence natural immunity, and suggest that ingestion of a fat-rich diet during training is detrimental to the immune system compared to the effect of a carbohydrate-rich diet.",
keywords = "Adult, Antigens, CD3, Antigens, CD56, Dietary Carbohydrates, Dietary Fats, Exercise, Humans, Immunity, Interferon-alpha, Interleukin-2, Killer Cells, Natural, Lymphocyte Subsets, Male, Oxygen Consumption, Physical Endurance, Receptors, IgG",
author = "Pedersen, {Bente Klarlund} and Helge, {J{\o}rn Wulff} and Erik Richter and Thomas Rohde and Bente Kiens",
year = "2000",
month = "5",
day = "1",
doi = "10.1007/s004210050657",
language = "English",
volume = "82",
pages = "98--102",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer",
number = "1-2",

}

RIS

TY - JOUR

T1 - Training and natural immunity

T2 - effects of diets rich in fat or carbohydrate

AU - Pedersen, Bente Klarlund

AU - Helge, Jørn Wulff

AU - Richter, Erik

AU - Rohde, Thomas

AU - Kiens, Bente

PY - 2000/5/1

Y1 - 2000/5/1

N2 - The purpose of the study was to investigate whether a carbohydrate-rich versus fat-rich diet influenced the effect of training on the immune system. Ten untrained young men ingested a carbohydrate-rich diet [65 energy percent (E%) carbohydrate] and ten subjects a fat-rich diet (62E% fat) while endurance training was performed 3-4 times a week for 7 weeks. Maximal oxygen uptake increased by 11% in both groups. Blood samples for immune monitoring were collected before and at the end of the study. Blood samples were also collected, in parallel, from 20 age-matched subjects, and data from these subjects were used to eliminate day-to-day variation in the immunological tests. Independently of diet, training increased the percentage of CD3-CD16+ CD56+ natural killer (NK) cells from [mean (SEM)] 14 (1) % to 20 (3) % (P = 0.05), whereas the NK-cell activity, either unstimulated or stimulated with interleukin (IL)-2 or interferon (IFN)-alpha, did not change. Furthermore, training did not influence the percentages of CD3+, CD4+, CD8+, CD19+ or CD14+ cells. However, when the two diet groups were compared, it was found that the NK-cell activity had increased in the group on the carbohydrate-rich diet [from 16 (3)% to 27 (2)%] and decreased in the group on the fat-rich diet [from 26 (2)% to 20 (4)%] in response to training. The effect of training on unstimulated NK-cell activity was significantly different between the groups (P = 0.007). These data indicate that diet manipulation during training may influence natural immunity, and suggest that ingestion of a fat-rich diet during training is detrimental to the immune system compared to the effect of a carbohydrate-rich diet.

AB - The purpose of the study was to investigate whether a carbohydrate-rich versus fat-rich diet influenced the effect of training on the immune system. Ten untrained young men ingested a carbohydrate-rich diet [65 energy percent (E%) carbohydrate] and ten subjects a fat-rich diet (62E% fat) while endurance training was performed 3-4 times a week for 7 weeks. Maximal oxygen uptake increased by 11% in both groups. Blood samples for immune monitoring were collected before and at the end of the study. Blood samples were also collected, in parallel, from 20 age-matched subjects, and data from these subjects were used to eliminate day-to-day variation in the immunological tests. Independently of diet, training increased the percentage of CD3-CD16+ CD56+ natural killer (NK) cells from [mean (SEM)] 14 (1) % to 20 (3) % (P = 0.05), whereas the NK-cell activity, either unstimulated or stimulated with interleukin (IL)-2 or interferon (IFN)-alpha, did not change. Furthermore, training did not influence the percentages of CD3+, CD4+, CD8+, CD19+ or CD14+ cells. However, when the two diet groups were compared, it was found that the NK-cell activity had increased in the group on the carbohydrate-rich diet [from 16 (3)% to 27 (2)%] and decreased in the group on the fat-rich diet [from 26 (2)% to 20 (4)%] in response to training. The effect of training on unstimulated NK-cell activity was significantly different between the groups (P = 0.007). These data indicate that diet manipulation during training may influence natural immunity, and suggest that ingestion of a fat-rich diet during training is detrimental to the immune system compared to the effect of a carbohydrate-rich diet.

KW - Adult

KW - Antigens, CD3

KW - Antigens, CD56

KW - Dietary Carbohydrates

KW - Dietary Fats

KW - Exercise

KW - Humans

KW - Immunity

KW - Interferon-alpha

KW - Interleukin-2

KW - Killer Cells, Natural

KW - Lymphocyte Subsets

KW - Male

KW - Oxygen Consumption

KW - Physical Endurance

KW - Receptors, IgG

U2 - 10.1007/s004210050657

DO - 10.1007/s004210050657

M3 - Journal article

C2 - 10879449

VL - 82

SP - 98

EP - 102

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

IS - 1-2

ER -

ID: 33864799