Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation.

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Standard

Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation. / Helge, Jørn W; Lundby, Carsten; Christensen, Dirk L; Langfort, Jozef; Messonnier, Laurent; Zacho, Morten; Andersen, Jesper; Saltin, Bengt.

I: Journal of Experimental Biology, Bind 206, Nr. Pt 6, 2003, s. 1075-83.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Helge, JW, Lundby, C, Christensen, DL, Langfort, J, Messonnier, L, Zacho, M, Andersen, J & Saltin, B 2003, 'Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation.', Journal of Experimental Biology, bind 206, nr. Pt 6, s. 1075-83.

APA

Helge, J. W., Lundby, C., Christensen, D. L., Langfort, J., Messonnier, L., Zacho, M., ... Saltin, B. (2003). Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation. Journal of Experimental Biology, 206(Pt 6), 1075-83.

Vancouver

Helge JW, Lundby C, Christensen DL, Langfort J, Messonnier L, Zacho M o.a. Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation. Journal of Experimental Biology. 2003;206(Pt 6):1075-83.

Author

Helge, Jørn W ; Lundby, Carsten ; Christensen, Dirk L ; Langfort, Jozef ; Messonnier, Laurent ; Zacho, Morten ; Andersen, Jesper ; Saltin, Bengt. / Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation. I: Journal of Experimental Biology. 2003 ; Bind 206, Nr. Pt 6. s. 1075-83.

Bibtex

@article{6c4feec0bc7b11dd8e02000ea68e967b,
title = "Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation.",
abstract = "This study investigates the adaptive response of the lower limb muscles and substrate oxidation during submaximal arm or leg exercise after a crossing of the Greenland icecap on cross-country skies. Before and after the 42-day expedition, four male subjects performed cycle ergometer and arm-cranking exercise on two separate days. On each occasion, the subjects exercised at two submaximal loads (arm exercise, 45 W and 100 W; leg exercise, 100 W and 200 W). In addition, peak oxygen uptake ((VO(2max))) was determined for both leg and arm exercise. Before and after the crossing, a muscle biopsy was obtained from the vastus lateralis and the triceps brachii muscles prior to exercise (N=3). After the crossing, body mass decreased by 5.7+/-0.5 kg (in four of four subjects), whereas (VO(2max)) was unchanged in the arm (3.1+/-0.2 l min(-1)) and leg (4.0+/-0.1 l min(-1)). Before the crossing, respiratory exchange ratio (RER) values were 0.84+/-0.02 and 0.96+/-0.02 during submaximal arm exercise and 0.82+/-0.02 and 0.91+/-0.01 during submaximal leg exercise at the low and high workloads, respectively. After the crossing, RER was lower (in three of four subjects) during arm exercise (0.74+/-0.02 and 0.81+/-0.01) but was higher (in three of four subjects) during leg exercise (0.92+/-0.02 and 0.96+/-0.01) at the low and high workloads, respectively. Citrate synthase and beta-hydroxy-acyl-CoA-dehydrogenase activity was decreased by approximately 29{\%} in vastus lateralis muscle and was unchanged in triceps brachii muscle. Fat oxidation during submaximal arm exercise was enhanced without a concomitant increase in the oxidative capacity of the triceps brachii muscle after the crossing. This contrasted with decreased fat oxidation during leg exercise, which occurred parallel to a decreased oxidative capacity in vastus lateralis muscle. Although the number of subjects is limited, these results imply that the adaptation pattern after long-term, prolonged, low-intensity, whole body exercise may vary dramatically among muscles.",
author = "Helge, {J{\o}rn W} and Carsten Lundby and Christensen, {Dirk L} and Jozef Langfort and Laurent Messonnier and Morten Zacho and Jesper Andersen and Bengt Saltin",
note = "Keywords: Adaptation, Physiological; Adult; Exercise Test; Food Habits; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Skiing",
year = "2003",
language = "English",
volume = "206",
pages = "1075--83",
journal = "Journal of Experimental Biology",
issn = "0022-0949",
publisher = "The/Company of Biologists Ltd.",
number = "Pt 6",

}

RIS

TY - JOUR

T1 - Skiing across the Greenland icecap: divergent effects on limb muscle adaptations and substrate oxidation.

AU - Helge, Jørn W

AU - Lundby, Carsten

AU - Christensen, Dirk L

AU - Langfort, Jozef

AU - Messonnier, Laurent

AU - Zacho, Morten

AU - Andersen, Jesper

AU - Saltin, Bengt

N1 - Keywords: Adaptation, Physiological; Adult; Exercise Test; Food Habits; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Skiing

PY - 2003

Y1 - 2003

N2 - This study investigates the adaptive response of the lower limb muscles and substrate oxidation during submaximal arm or leg exercise after a crossing of the Greenland icecap on cross-country skies. Before and after the 42-day expedition, four male subjects performed cycle ergometer and arm-cranking exercise on two separate days. On each occasion, the subjects exercised at two submaximal loads (arm exercise, 45 W and 100 W; leg exercise, 100 W and 200 W). In addition, peak oxygen uptake ((VO(2max))) was determined for both leg and arm exercise. Before and after the crossing, a muscle biopsy was obtained from the vastus lateralis and the triceps brachii muscles prior to exercise (N=3). After the crossing, body mass decreased by 5.7+/-0.5 kg (in four of four subjects), whereas (VO(2max)) was unchanged in the arm (3.1+/-0.2 l min(-1)) and leg (4.0+/-0.1 l min(-1)). Before the crossing, respiratory exchange ratio (RER) values were 0.84+/-0.02 and 0.96+/-0.02 during submaximal arm exercise and 0.82+/-0.02 and 0.91+/-0.01 during submaximal leg exercise at the low and high workloads, respectively. After the crossing, RER was lower (in three of four subjects) during arm exercise (0.74+/-0.02 and 0.81+/-0.01) but was higher (in three of four subjects) during leg exercise (0.92+/-0.02 and 0.96+/-0.01) at the low and high workloads, respectively. Citrate synthase and beta-hydroxy-acyl-CoA-dehydrogenase activity was decreased by approximately 29% in vastus lateralis muscle and was unchanged in triceps brachii muscle. Fat oxidation during submaximal arm exercise was enhanced without a concomitant increase in the oxidative capacity of the triceps brachii muscle after the crossing. This contrasted with decreased fat oxidation during leg exercise, which occurred parallel to a decreased oxidative capacity in vastus lateralis muscle. Although the number of subjects is limited, these results imply that the adaptation pattern after long-term, prolonged, low-intensity, whole body exercise may vary dramatically among muscles.

AB - This study investigates the adaptive response of the lower limb muscles and substrate oxidation during submaximal arm or leg exercise after a crossing of the Greenland icecap on cross-country skies. Before and after the 42-day expedition, four male subjects performed cycle ergometer and arm-cranking exercise on two separate days. On each occasion, the subjects exercised at two submaximal loads (arm exercise, 45 W and 100 W; leg exercise, 100 W and 200 W). In addition, peak oxygen uptake ((VO(2max))) was determined for both leg and arm exercise. Before and after the crossing, a muscle biopsy was obtained from the vastus lateralis and the triceps brachii muscles prior to exercise (N=3). After the crossing, body mass decreased by 5.7+/-0.5 kg (in four of four subjects), whereas (VO(2max)) was unchanged in the arm (3.1+/-0.2 l min(-1)) and leg (4.0+/-0.1 l min(-1)). Before the crossing, respiratory exchange ratio (RER) values were 0.84+/-0.02 and 0.96+/-0.02 during submaximal arm exercise and 0.82+/-0.02 and 0.91+/-0.01 during submaximal leg exercise at the low and high workloads, respectively. After the crossing, RER was lower (in three of four subjects) during arm exercise (0.74+/-0.02 and 0.81+/-0.01) but was higher (in three of four subjects) during leg exercise (0.92+/-0.02 and 0.96+/-0.01) at the low and high workloads, respectively. Citrate synthase and beta-hydroxy-acyl-CoA-dehydrogenase activity was decreased by approximately 29% in vastus lateralis muscle and was unchanged in triceps brachii muscle. Fat oxidation during submaximal arm exercise was enhanced without a concomitant increase in the oxidative capacity of the triceps brachii muscle after the crossing. This contrasted with decreased fat oxidation during leg exercise, which occurred parallel to a decreased oxidative capacity in vastus lateralis muscle. Although the number of subjects is limited, these results imply that the adaptation pattern after long-term, prolonged, low-intensity, whole body exercise may vary dramatically among muscles.

M3 - Journal article

VL - 206

SP - 1075

EP - 1083

JO - Journal of Experimental Biology

JF - Journal of Experimental Biology

SN - 0022-0949

IS - Pt 6

ER -

ID: 8777008