Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study

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Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study. / Thomsen, Simon Francis; Kyvik, Kirsten Ohm; Skadhauge, Lars Rauff; Steffensen, Ida; Backer, Vibeke.

I: Clinical Respiratory Journal, Bind 3, Nr. 2, 01.04.2009, s. 82-4.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Thomsen, SF, Kyvik, KO, Skadhauge, LR, Steffensen, I & Backer, V 2009, 'Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study', Clinical Respiratory Journal, bind 3, nr. 2, s. 82-4. https://doi.org/10.1111/j.1752-699X.2008.00113.x, https://doi.org/10.1111/j.1752-699X.2008.00113.x

APA

Thomsen, S. F., Kyvik, K. O., Skadhauge, L. R., Steffensen, I., & Backer, V. (2009). Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study. Clinical Respiratory Journal, 3(2), 82-4. https://doi.org/10.1111/j.1752-699X.2008.00113.x, https://doi.org/10.1111/j.1752-699X.2008.00113.x

Vancouver

Thomsen SF, Kyvik KO, Skadhauge LR, Steffensen I, Backer V. Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study. Clinical Respiratory Journal. 2009 apr 1;3(2):82-4. https://doi.org/10.1111/j.1752-699X.2008.00113.x, https://doi.org/10.1111/j.1752-699X.2008.00113.x

Author

Thomsen, Simon Francis ; Kyvik, Kirsten Ohm ; Skadhauge, Lars Rauff ; Steffensen, Ida ; Backer, Vibeke. / Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study. I: Clinical Respiratory Journal. 2009 ; Bind 3, Nr. 2. s. 82-4.

Bibtex

@article{54e80b4088d111df928f000ea68e967b,
title = "Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study",
abstract = "BACKGROUND: Little is known about the relation between regular use of non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of asthma at the population level. The aim of this study was to examine a possible association between intake of NSAIDs and risk of adult-onset asthma. METHODS: Using data from two multidisciplinary postal questionnaire surveys concerning health and lifestyle, we prospectively studied 19 349 adult twins enrolled in the nationwide Danish Twin Registry. RESULTS: We found a higher prevalence of new-onset asthma in subjects who used NSAIDs (other than aspirin) regularly compared with non-users (7.7{\%} vs 4.3{\%}), OR = 1.87 (1.25-2.81), P = 0.002. The result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema and intake of medications other than NSAIDs, OR = 1.90 (1.26-2.85), P = 0.002. CONCLUSIONS: Regular use of NSAIDs other than aspirin may be a risk factor for adult-onset asthma. This observation must be accommodated in explanations of the relationship between use of analgesics and risk of asthma.",
author = "Thomsen, {Simon Francis} and Kyvik, {Kirsten Ohm} and Skadhauge, {Lars Rauff} and Ida Steffensen and Vibeke Backer",
note = "Keywords: Adolescent; Adult; Age Distribution; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Confidence Intervals; Cross-Sectional Studies; Denmark; Diseases in Twins; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Odds Ratio; Prevalence; Probability; Questionnaires; Reference Values; Risk Assessment; Sex Distribution; Young Adult",
year = "2009",
month = "4",
day = "1",
doi = "10.1111/j.1752-699X.2008.00113.x",
language = "English",
volume = "3",
pages = "82--4",
journal = "Clinical Respiratory Journal",
issn = "1752-6981",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Regular use of non-steroidal anti-inflammatory drugs increases the risk of adult-onset asthma: a population-based follow-up study

AU - Thomsen, Simon Francis

AU - Kyvik, Kirsten Ohm

AU - Skadhauge, Lars Rauff

AU - Steffensen, Ida

AU - Backer, Vibeke

N1 - Keywords: Adolescent; Adult; Age Distribution; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Confidence Intervals; Cross-Sectional Studies; Denmark; Diseases in Twins; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Odds Ratio; Prevalence; Probability; Questionnaires; Reference Values; Risk Assessment; Sex Distribution; Young Adult

PY - 2009/4/1

Y1 - 2009/4/1

N2 - BACKGROUND: Little is known about the relation between regular use of non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of asthma at the population level. The aim of this study was to examine a possible association between intake of NSAIDs and risk of adult-onset asthma. METHODS: Using data from two multidisciplinary postal questionnaire surveys concerning health and lifestyle, we prospectively studied 19 349 adult twins enrolled in the nationwide Danish Twin Registry. RESULTS: We found a higher prevalence of new-onset asthma in subjects who used NSAIDs (other than aspirin) regularly compared with non-users (7.7% vs 4.3%), OR = 1.87 (1.25-2.81), P = 0.002. The result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema and intake of medications other than NSAIDs, OR = 1.90 (1.26-2.85), P = 0.002. CONCLUSIONS: Regular use of NSAIDs other than aspirin may be a risk factor for adult-onset asthma. This observation must be accommodated in explanations of the relationship between use of analgesics and risk of asthma.

AB - BACKGROUND: Little is known about the relation between regular use of non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of asthma at the population level. The aim of this study was to examine a possible association between intake of NSAIDs and risk of adult-onset asthma. METHODS: Using data from two multidisciplinary postal questionnaire surveys concerning health and lifestyle, we prospectively studied 19 349 adult twins enrolled in the nationwide Danish Twin Registry. RESULTS: We found a higher prevalence of new-onset asthma in subjects who used NSAIDs (other than aspirin) regularly compared with non-users (7.7% vs 4.3%), OR = 1.87 (1.25-2.81), P = 0.002. The result remained significant after adjusting for sex, age, smoking, BMI, hay fever, eczema and intake of medications other than NSAIDs, OR = 1.90 (1.26-2.85), P = 0.002. CONCLUSIONS: Regular use of NSAIDs other than aspirin may be a risk factor for adult-onset asthma. This observation must be accommodated in explanations of the relationship between use of analgesics and risk of asthma.

U2 - 10.1111/j.1752-699X.2008.00113.x

DO - 10.1111/j.1752-699X.2008.00113.x

M3 - Journal article

C2 - 20298382

VL - 3

SP - 82

EP - 84

JO - Clinical Respiratory Journal

JF - Clinical Respiratory Journal

SN - 1752-6981

IS - 2

ER -

ID: 20649255