Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

Standard

Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction : First small animal cardiac (82)Rb-PET. / Clemmensen, Andreas Ettrup; Ghotbi, Adam Ali; Bodholdt, Rasmus Poul; Hag, Anne Mette Fisker; Hasbak, Philip; Ripa, Rasmus Sejersten; Kjaer, Andreas.

I: Journal of Nuclear Cardiology, Bind 24, Nr. 2, 02.2017, s. 750-752.

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

Harvard

Clemmensen, AE, Ghotbi, AA, Bodholdt, RP, Hag, AMF, Hasbak, P, Ripa, RS & Kjaer, A 2017, 'Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET', Journal of Nuclear Cardiology, bind 24, nr. 2, s. 750-752. https://doi.org/10.1007/s12350-016-0564-6

APA

Clemmensen, A. E., Ghotbi, A. A., Bodholdt, R. P., Hag, A. M. F., Hasbak, P., Ripa, R. S., & Kjaer, A. (2017). Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET. Journal of Nuclear Cardiology, 24(2), 750-752. https://doi.org/10.1007/s12350-016-0564-6

Vancouver

Clemmensen AE, Ghotbi AA, Bodholdt RP, Hag AMF, Hasbak P, Ripa RS o.a. Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET. Journal of Nuclear Cardiology. 2017 feb;24(2):750-752. https://doi.org/10.1007/s12350-016-0564-6

Author

Clemmensen, Andreas Ettrup ; Ghotbi, Adam Ali ; Bodholdt, Rasmus Poul ; Hag, Anne Mette Fisker ; Hasbak, Philip ; Ripa, Rasmus Sejersten ; Kjaer, Andreas. / Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction : First small animal cardiac (82)Rb-PET. I: Journal of Nuclear Cardiology. 2017 ; Bind 24, Nr. 2. s. 750-752.

Bibtex

@article{4a2d403007b74ef88b793dfd952bc623,
title = "Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET",
abstract = "Assessing myocardial perfusion using 82Rb-PET is emerging as a valuable clinical tool.1,2 The rapid decay (T½ = 76 s) allows for absolute quantification of both rest and stress perfusion within 30 minutes. In addition to evaluation of epicardial disease with perfusion defects, also evaluation of balanced coronary and small vessel disease is possible. For further evaluation of how 82Rb-PET can be used clinically, pre-clinical application of the method would be valuable. However, so far no data on the use of 82Rb-PET in small animals have been published nor has the use of 82Rb-PET, to the best of our knowledge, been successfully tried. Therefore, we wanted to develop and test the applicability of the method in rats, despite the high positron range of 82Rb. To do so, we adapted the clinical method and tested it in rats with experimentally induced myocardial infarction.",
author = "Clemmensen, {Andreas Ettrup} and Ghotbi, {Adam Ali} and Bodholdt, {Rasmus Poul} and Hag, {Anne Mette Fisker} and Philip Hasbak and Ripa, {Rasmus Sejersten} and Andreas Kjaer",
year = "2017",
month = "2",
doi = "10.1007/s12350-016-0564-6",
language = "English",
volume = "24",
pages = "750--752",
journal = "Journal of Nuclear Cardiology",
issn = "1071-3581",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction

T2 - First small animal cardiac (82)Rb-PET

AU - Clemmensen, Andreas Ettrup

AU - Ghotbi, Adam Ali

AU - Bodholdt, Rasmus Poul

AU - Hag, Anne Mette Fisker

AU - Hasbak, Philip

AU - Ripa, Rasmus Sejersten

AU - Kjaer, Andreas

PY - 2017/2

Y1 - 2017/2

N2 - Assessing myocardial perfusion using 82Rb-PET is emerging as a valuable clinical tool.1,2 The rapid decay (T½ = 76 s) allows for absolute quantification of both rest and stress perfusion within 30 minutes. In addition to evaluation of epicardial disease with perfusion defects, also evaluation of balanced coronary and small vessel disease is possible. For further evaluation of how 82Rb-PET can be used clinically, pre-clinical application of the method would be valuable. However, so far no data on the use of 82Rb-PET in small animals have been published nor has the use of 82Rb-PET, to the best of our knowledge, been successfully tried. Therefore, we wanted to develop and test the applicability of the method in rats, despite the high positron range of 82Rb. To do so, we adapted the clinical method and tested it in rats with experimentally induced myocardial infarction.

AB - Assessing myocardial perfusion using 82Rb-PET is emerging as a valuable clinical tool.1,2 The rapid decay (T½ = 76 s) allows for absolute quantification of both rest and stress perfusion within 30 minutes. In addition to evaluation of epicardial disease with perfusion defects, also evaluation of balanced coronary and small vessel disease is possible. For further evaluation of how 82Rb-PET can be used clinically, pre-clinical application of the method would be valuable. However, so far no data on the use of 82Rb-PET in small animals have been published nor has the use of 82Rb-PET, to the best of our knowledge, been successfully tried. Therefore, we wanted to develop and test the applicability of the method in rats, despite the high positron range of 82Rb. To do so, we adapted the clinical method and tested it in rats with experimentally induced myocardial infarction.

U2 - 10.1007/s12350-016-0564-6

DO - 10.1007/s12350-016-0564-6

M3 - Letter

VL - 24

SP - 750

EP - 752

JO - Journal of Nuclear Cardiology

JF - Journal of Nuclear Cardiology

SN - 1071-3581

IS - 2

ER -

ID: 174693730