Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet

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Standard

Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet. / Helge, Jørn Wulff; Watt, Peter W; Richter, Erik A; Rennie, Michael J; Kiens, Bente.

I: Journal of Applied Physiology, Bind 93, Nr. 5, 2002, s. 1797-1805.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Helge, JW, Watt, PW, Richter, EA, Rennie, MJ & Kiens, B 2002, 'Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet', Journal of Applied Physiology, bind 93, nr. 5, s. 1797-1805. https://doi.org/10.1152/japplphysiol.00420.2002

APA

Helge, J. W., Watt, P. W., Richter, E. A., Rennie, M. J., & Kiens, B. (2002). Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet. Journal of Applied Physiology, 93(5), 1797-1805. https://doi.org/10.1152/japplphysiol.00420.2002

Vancouver

Helge JW, Watt PW, Richter EA, Rennie MJ, Kiens B. Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet. Journal of Applied Physiology. 2002;93(5):1797-1805. https://doi.org/10.1152/japplphysiol.00420.2002

Author

Helge, Jørn Wulff ; Watt, Peter W ; Richter, Erik A ; Rennie, Michael J ; Kiens, Bente. / Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet. I: Journal of Applied Physiology. 2002 ; Bind 93, Nr. 5. s. 1797-1805.

Bibtex

@article{d594ce0074c511dbbee902004c4f4f50,
title = "Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet",
abstract = "We tested the hypothesis that a shift to carbohydrate diet after prolonged adaptation to fat diet would lead to decreased glucose uptake and impaired muscle glycogen breakdown during exercise compared with ingestion of a carbohydrate diet all along. We studied 13 untrained men; 7 consumed a high-fat (Fat-CHO; 62{\%} fat, 21{\%} carbohydrate) and 6 a high-carbohydrate diet (CHO; 20{\%} fat, 65{\%} carbohydrate) for 7 wk, and thereafter both groups consumed the carbohydrate diet for an eighth week. Training was performed throughout. After 8 wk, during 60 min of exercise (71 +/- 1{\%} pretraining maximal oxygen uptake) average leg glucose uptake (1.00 +/- 0.07 vs. 1.55 +/- 0.21 mmol/min) was lower (P <0.05) in Fat-CHO than in CHO. The rate of muscle glycogen breakdown was similar (4.4 +/- 0.5 vs. 4.2 +/- 0.7 mmol. min(-1). kg dry wt(-1)) despite a significantly higher preexercise glycogen concentration (872 +/- 59 vs. 688 +/- 43 mmol/kg dry wt) in Fat-CHO than in CHO. In conclusion, shift to carbohydrate diet after prolonged adaptation to fat diet and training causes increased resting muscle glycogen levels but impaired leg glucose uptake and similar muscle glycogen breakdown, despite higher resting levels, compared with when the carbohydrate diet is consumed throughout training.",
keywords = "Adaptation, Physiological, Adult, Dietary Carbohydrates, Dietary Fats, Dose-Response Relationship, Drug, Glucose, Glycogen, Humans, Leg, Male, Muscle, Skeletal, Osmolar Concentration, Physical Education and Training, Regional Blood Flow, Rest",
author = "Helge, {J{\o}rn Wulff} and Watt, {Peter W} and Richter, {Erik A} and Rennie, {Michael J} and Bente Kiens",
note = "PUF 2002 5200 090",
year = "2002",
doi = "10.1152/japplphysiol.00420.2002",
language = "English",
volume = "93",
pages = "1797--1805",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "5",

}

RIS

TY - JOUR

T1 - Partial restoration of dietary fat induced metabolic adaptations to training by 7 days of carbohydrate diet

AU - Helge, Jørn Wulff

AU - Watt, Peter W

AU - Richter, Erik A

AU - Rennie, Michael J

AU - Kiens, Bente

N1 - PUF 2002 5200 090

PY - 2002

Y1 - 2002

N2 - We tested the hypothesis that a shift to carbohydrate diet after prolonged adaptation to fat diet would lead to decreased glucose uptake and impaired muscle glycogen breakdown during exercise compared with ingestion of a carbohydrate diet all along. We studied 13 untrained men; 7 consumed a high-fat (Fat-CHO; 62% fat, 21% carbohydrate) and 6 a high-carbohydrate diet (CHO; 20% fat, 65% carbohydrate) for 7 wk, and thereafter both groups consumed the carbohydrate diet for an eighth week. Training was performed throughout. After 8 wk, during 60 min of exercise (71 +/- 1% pretraining maximal oxygen uptake) average leg glucose uptake (1.00 +/- 0.07 vs. 1.55 +/- 0.21 mmol/min) was lower (P <0.05) in Fat-CHO than in CHO. The rate of muscle glycogen breakdown was similar (4.4 +/- 0.5 vs. 4.2 +/- 0.7 mmol. min(-1). kg dry wt(-1)) despite a significantly higher preexercise glycogen concentration (872 +/- 59 vs. 688 +/- 43 mmol/kg dry wt) in Fat-CHO than in CHO. In conclusion, shift to carbohydrate diet after prolonged adaptation to fat diet and training causes increased resting muscle glycogen levels but impaired leg glucose uptake and similar muscle glycogen breakdown, despite higher resting levels, compared with when the carbohydrate diet is consumed throughout training.

AB - We tested the hypothesis that a shift to carbohydrate diet after prolonged adaptation to fat diet would lead to decreased glucose uptake and impaired muscle glycogen breakdown during exercise compared with ingestion of a carbohydrate diet all along. We studied 13 untrained men; 7 consumed a high-fat (Fat-CHO; 62% fat, 21% carbohydrate) and 6 a high-carbohydrate diet (CHO; 20% fat, 65% carbohydrate) for 7 wk, and thereafter both groups consumed the carbohydrate diet for an eighth week. Training was performed throughout. After 8 wk, during 60 min of exercise (71 +/- 1% pretraining maximal oxygen uptake) average leg glucose uptake (1.00 +/- 0.07 vs. 1.55 +/- 0.21 mmol/min) was lower (P <0.05) in Fat-CHO than in CHO. The rate of muscle glycogen breakdown was similar (4.4 +/- 0.5 vs. 4.2 +/- 0.7 mmol. min(-1). kg dry wt(-1)) despite a significantly higher preexercise glycogen concentration (872 +/- 59 vs. 688 +/- 43 mmol/kg dry wt) in Fat-CHO than in CHO. In conclusion, shift to carbohydrate diet after prolonged adaptation to fat diet and training causes increased resting muscle glycogen levels but impaired leg glucose uptake and similar muscle glycogen breakdown, despite higher resting levels, compared with when the carbohydrate diet is consumed throughout training.

KW - Adaptation, Physiological

KW - Adult

KW - Dietary Carbohydrates

KW - Dietary Fats

KW - Dose-Response Relationship, Drug

KW - Glucose

KW - Glycogen

KW - Humans

KW - Leg

KW - Male

KW - Muscle, Skeletal

KW - Osmolar Concentration

KW - Physical Education and Training

KW - Regional Blood Flow

KW - Rest

U2 - 10.1152/japplphysiol.00420.2002

DO - 10.1152/japplphysiol.00420.2002

M3 - Journal article

VL - 93

SP - 1797

EP - 1805

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 5

ER -

ID: 139702