Ny markør ved trombotisk trombocytopenisk purpura.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Jens Peter Gøtze, Andreas Hillarp, Anders Lindblom, Peter Björk, Karin Strandberg, Lars Bo Nielsen

Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP.
Udgivelsesdato: 2008-Aug-11
OriginalsprogDansk
TidsskriftUgeskrift for læger
Vol/bind170
Udgave nummer33
Sider (fra-til)2446-9
Antal sider3
ISSN0041-5782
StatusUdgivet - 2008

ID: 8466128