Ny markør ved trombotisk trombocytopenisk purpura.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Gotze, Jens P.
  • Andreas Hillarp
  • Anders Lindblom
  • Peter Björk
  • Karin Strandberg
  • Lars Bo Nielsen
Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregation. Measurement of ADAMTS-13 activity is useful for the diagnosis of TTP and may also be relevant as a prognostic test for recurrent TTP.
Udgivelsesdato: 2008-Aug-11
OriginalsprogDansk
TidsskriftUgeskrift for læger
Vol/bind170
Udgave nummer33
Sider (fra-til)2446-9
Antal sider3
ISSN0041-5782
StatusUdgivet - 2008

ID: 8466128