Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes

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Standard

Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes. / Helge, Jørn Wulff; Tobin, L; Drachmann, Tue; Hellgren, Lars; Dela, F; Galbo, H.

I: European Journal of Applied Physiology, Bind 112, 2012, s. 911-18.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Helge, JW, Tobin, L, Drachmann, T, Hellgren, L, Dela, F & Galbo, H 2012, 'Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes', European Journal of Applied Physiology, bind 112, s. 911-18. https://doi.org/10.1007/s00421-011-2041-x

APA

Helge, J. W., Tobin, L., Drachmann, T., Hellgren, L., Dela, F., & Galbo, H. (2012). Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes. European Journal of Applied Physiology, 112, 911-18. https://doi.org/10.1007/s00421-011-2041-x

Vancouver

Helge JW, Tobin L, Drachmann T, Hellgren L, Dela F, Galbo H. Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes. European Journal of Applied Physiology. 2012;112:911-18. https://doi.org/10.1007/s00421-011-2041-x

Author

Helge, Jørn Wulff ; Tobin, L ; Drachmann, Tue ; Hellgren, Lars ; Dela, F ; Galbo, H. / Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes. I: European Journal of Applied Physiology. 2012 ; Bind 112. s. 911-18.

Bibtex

@article{a2d4ddfd0eb84100888baeb4eefd0d55,
title = "Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes",
abstract = "This study aimed at investigating the effect of prolonged adaptation to fat- or carbohydrate-rich diet on muscle ceramide in type 2 diabetes patients, using a longitudinal crossover study. Eleven type 2 diabetes patients consumed isocaloric fat- or carbohydrate-rich diet for 3 weeks in random order. After each dietary intervention period, muscle glycogen, triacylglycerol and ceramide content and plasma concentrations of insulin, adiponectin, glucose and FFA were determined. Insulin resistance was assessed by HOMA2 calculation. After the dietary period, plasma glucose and insulin, insulin sensitivity, muscle glycogen, triacylglycerol and ceramide content were similar. Plasma adiponectin concentration was significantly higher after fat compared with carbohydrate-rich diet. Results indicated that following fat-rich diet intake muscle ceramide and triacylglycerol concentrations were not different compared with that after carbohydrate-rich diet. Furthermore, plasma adiponectin concentration was higher after fat-rich compared with carbohydrate-rich diet, but insulin sensitivity remained similar despite the major difference in dietary macronutrient composition.",
author = "Helge, {J{\o}rn Wulff} and L Tobin and Tue Drachmann and Lars Hellgren and F Dela and H Galbo",
year = "2012",
doi = "10.1007/s00421-011-2041-x",
language = "English",
volume = "112",
pages = "911--18",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes

AU - Helge, Jørn Wulff

AU - Tobin, L

AU - Drachmann, Tue

AU - Hellgren, Lars

AU - Dela, F

AU - Galbo, H

PY - 2012

Y1 - 2012

N2 - This study aimed at investigating the effect of prolonged adaptation to fat- or carbohydrate-rich diet on muscle ceramide in type 2 diabetes patients, using a longitudinal crossover study. Eleven type 2 diabetes patients consumed isocaloric fat- or carbohydrate-rich diet for 3 weeks in random order. After each dietary intervention period, muscle glycogen, triacylglycerol and ceramide content and plasma concentrations of insulin, adiponectin, glucose and FFA were determined. Insulin resistance was assessed by HOMA2 calculation. After the dietary period, plasma glucose and insulin, insulin sensitivity, muscle glycogen, triacylglycerol and ceramide content were similar. Plasma adiponectin concentration was significantly higher after fat compared with carbohydrate-rich diet. Results indicated that following fat-rich diet intake muscle ceramide and triacylglycerol concentrations were not different compared with that after carbohydrate-rich diet. Furthermore, plasma adiponectin concentration was higher after fat-rich compared with carbohydrate-rich diet, but insulin sensitivity remained similar despite the major difference in dietary macronutrient composition.

AB - This study aimed at investigating the effect of prolonged adaptation to fat- or carbohydrate-rich diet on muscle ceramide in type 2 diabetes patients, using a longitudinal crossover study. Eleven type 2 diabetes patients consumed isocaloric fat- or carbohydrate-rich diet for 3 weeks in random order. After each dietary intervention period, muscle glycogen, triacylglycerol and ceramide content and plasma concentrations of insulin, adiponectin, glucose and FFA were determined. Insulin resistance was assessed by HOMA2 calculation. After the dietary period, plasma glucose and insulin, insulin sensitivity, muscle glycogen, triacylglycerol and ceramide content were similar. Plasma adiponectin concentration was significantly higher after fat compared with carbohydrate-rich diet. Results indicated that following fat-rich diet intake muscle ceramide and triacylglycerol concentrations were not different compared with that after carbohydrate-rich diet. Furthermore, plasma adiponectin concentration was higher after fat-rich compared with carbohydrate-rich diet, but insulin sensitivity remained similar despite the major difference in dietary macronutrient composition.

U2 - 10.1007/s00421-011-2041-x

DO - 10.1007/s00421-011-2041-x

M3 - Journal article

C2 - 21695523

VL - 112

SP - 911

EP - 918

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

ER -

ID: 33861421