Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

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Standard

Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration. / Larsen, Steen; Rabøl, R; Hansen, C N; Madsbad, S; Helge, J W; Dela, F.

I: Diabetologia, Bind 55, Nr. 2, 2012, s. 443-9.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Larsen, S, Rabøl, R, Hansen, CN, Madsbad, S, Helge, JW & Dela, F 2012, 'Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration', Diabetologia, bind 55, nr. 2, s. 443-9. https://doi.org/10.1007/s00125-011-2340-0

APA

Larsen, S., Rabøl, R., Hansen, C. N., Madsbad, S., Helge, J. W., & Dela, F. (2012). Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration. Diabetologia, 55(2), 443-9. https://doi.org/10.1007/s00125-011-2340-0

Vancouver

Larsen S, Rabøl R, Hansen CN, Madsbad S, Helge JW, Dela F. Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration. Diabetologia. 2012;55(2):443-9. https://doi.org/10.1007/s00125-011-2340-0

Author

Larsen, Steen ; Rabøl, R ; Hansen, C N ; Madsbad, S ; Helge, J W ; Dela, F. / Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration. I: Diabetologia. 2012 ; Bind 55, Nr. 2. s. 443-9.

Bibtex

@article{877c8be05d82410d968c89c88aa26ed4,
title = "Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration",
abstract = "The glucose-lowering drug metformin has been shown to inhibit complex I of the mitochondrial electron transport chain in skeletal muscle. To investigate this effect in vivo we studied skeletal muscle mitochondrial respiratory capacity and content from patients with type 2 diabetes treated with metformin (n = 14) or sulfonylurea (n = 8) and healthy control (n = 18) participants.",
keywords = "Blood Glucose, Body Mass Index, Case-Control Studies, Cell Respiration, Citrate (si)-Synthase, Diabetes Mellitus, Type 2, Electron Transport Complex I, Hemoglobin A, Glycosylated, Humans, Hypoglycemic Agents, Insulin, Male, Metformin, Middle Aged, Models, Biological, Muscle, Skeletal, Oxygen Consumption, Sulfonylurea Compounds",
author = "Steen Larsen and R Rab{\o}l and Hansen, {C N} and S Madsbad and Helge, {J W} and F Dela",
year = "2012",
doi = "10.1007/s00125-011-2340-0",
language = "English",
volume = "55",
pages = "443--9",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

AU - Larsen, Steen

AU - Rabøl, R

AU - Hansen, C N

AU - Madsbad, S

AU - Helge, J W

AU - Dela, F

PY - 2012

Y1 - 2012

N2 - The glucose-lowering drug metformin has been shown to inhibit complex I of the mitochondrial electron transport chain in skeletal muscle. To investigate this effect in vivo we studied skeletal muscle mitochondrial respiratory capacity and content from patients with type 2 diabetes treated with metformin (n = 14) or sulfonylurea (n = 8) and healthy control (n = 18) participants.

AB - The glucose-lowering drug metformin has been shown to inhibit complex I of the mitochondrial electron transport chain in skeletal muscle. To investigate this effect in vivo we studied skeletal muscle mitochondrial respiratory capacity and content from patients with type 2 diabetes treated with metformin (n = 14) or sulfonylurea (n = 8) and healthy control (n = 18) participants.

KW - Blood Glucose

KW - Body Mass Index

KW - Case-Control Studies

KW - Cell Respiration

KW - Citrate (si)-Synthase

KW - Diabetes Mellitus, Type 2

KW - Electron Transport Complex I

KW - Hemoglobin A, Glycosylated

KW - Humans

KW - Hypoglycemic Agents

KW - Insulin

KW - Male

KW - Metformin

KW - Middle Aged

KW - Models, Biological

KW - Muscle, Skeletal

KW - Oxygen Consumption

KW - Sulfonylurea Compounds

U2 - 10.1007/s00125-011-2340-0

DO - 10.1007/s00125-011-2340-0

M3 - Journal article

C2 - 22009334

VL - 55

SP - 443

EP - 449

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 2

ER -

ID: 40176660