Knee osteoarthritis among airport baggage handlers: A prospective cohort study

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Standard

Knee osteoarthritis among airport baggage handlers : A prospective cohort study. / Mikkelsen, Sigurd; Pedersen, Ellen B; Brauer, Charlotte; Møller, Karina L; Alkjaer, Tine; Koblauch, Henrik; Simonsen, Erik B; Thygesen, Lau C.

I: American Journal of Industrial Medicine, Bind 62, Nr. 11, 2019, s. 951-960.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Mikkelsen, S, Pedersen, EB, Brauer, C, Møller, KL, Alkjaer, T, Koblauch, H, Simonsen, EB & Thygesen, LC 2019, 'Knee osteoarthritis among airport baggage handlers: A prospective cohort study', American Journal of Industrial Medicine, bind 62, nr. 11, s. 951-960. https://doi.org/10.1002/ajim.23044

APA

Mikkelsen, S., Pedersen, E. B., Brauer, C., Møller, K. L., Alkjaer, T., Koblauch, H., ... Thygesen, L. C. (2019). Knee osteoarthritis among airport baggage handlers: A prospective cohort study. American Journal of Industrial Medicine, 62(11), 951-960. https://doi.org/10.1002/ajim.23044

Vancouver

Mikkelsen S, Pedersen EB, Brauer C, Møller KL, Alkjaer T, Koblauch H o.a. Knee osteoarthritis among airport baggage handlers: A prospective cohort study. American Journal of Industrial Medicine. 2019;62(11):951-960. https://doi.org/10.1002/ajim.23044

Author

Mikkelsen, Sigurd ; Pedersen, Ellen B ; Brauer, Charlotte ; Møller, Karina L ; Alkjaer, Tine ; Koblauch, Henrik ; Simonsen, Erik B ; Thygesen, Lau C. / Knee osteoarthritis among airport baggage handlers : A prospective cohort study. I: American Journal of Industrial Medicine. 2019 ; Bind 62, Nr. 11. s. 951-960.

Bibtex

@article{5c9e127b4bef4af3b794c2be615a6cec,
title = "Knee osteoarthritis among airport baggage handlers: A prospective cohort study",
abstract = "BACKGROUND: Knee osteoarthritis is a common and often disabling disorder, which has been related to knee-straining work. However, exposure response relations are uncertain and there are few prospective studies. We studied prospectively if incident knee osteoarthritis is associated with cumulative exposure as an airport baggage handler, lifting on average 5000 kg/d.METHODS: The study is based on the Copenhagen Airport Cohort, a historical cohort of male baggage handlers and a reference group of unskilled men from the greater Copenhagen area, followed from 1990 to 2012. Cumulative years of employment as a baggage handler was based on information from company employment and union registers. Outcome was first hospital admission with a discharge diagnosis of knee osteoarthritis and/or knee replacement, ascertained from the Danish National Patient Register.RESULTS: The cohort contained 3442 baggage handlers and 65 511 workers in the reference group. The unadjusted incidence rate ratio (IRR) of knee osteoarthritis increased steeply with cumulative years as a baggage handler. Although the exposure-response pattern became weaker and statistically nonsignificant (P ≈ .10) when adjusting for age, the risk of knee osteoarthritis was still increased in baggage handlers at the highest exposure level. Additional analyses showed that the association between age and osteoarthritis was stronger for baggage handlers (IRR = 2.09; 95{\%} CI: 1.68-2.60) than for referents (IRR = 1.58; 95{\%} CI: 1.53-1.63), indicating that knee osteoarthritis occurred at a younger age among baggage handlers than in the reference group.CONCLUSIONS: The results of this prospective cohort study support that long-term heavy lifting increases the risk of knee osteoarthritis.",
author = "Sigurd Mikkelsen and Pedersen, {Ellen B} and Charlotte Brauer and M{\o}ller, {Karina L} and Tine Alkjaer and Henrik Koblauch and Simonsen, {Erik B} and Thygesen, {Lau C}",
note = "{\circledC} 2019 Wiley Periodicals, Inc.",
year = "2019",
doi = "10.1002/ajim.23044",
language = "English",
volume = "62",
pages = "951--960",
journal = "American Journal of Industrial Medicine",
issn = "0271-3586",
publisher = "JohnWiley & Sons, Inc.",
number = "11",

}

RIS

TY - JOUR

T1 - Knee osteoarthritis among airport baggage handlers

T2 - A prospective cohort study

AU - Mikkelsen, Sigurd

AU - Pedersen, Ellen B

AU - Brauer, Charlotte

AU - Møller, Karina L

AU - Alkjaer, Tine

AU - Koblauch, Henrik

AU - Simonsen, Erik B

AU - Thygesen, Lau C

N1 - © 2019 Wiley Periodicals, Inc.

PY - 2019

Y1 - 2019

N2 - BACKGROUND: Knee osteoarthritis is a common and often disabling disorder, which has been related to knee-straining work. However, exposure response relations are uncertain and there are few prospective studies. We studied prospectively if incident knee osteoarthritis is associated with cumulative exposure as an airport baggage handler, lifting on average 5000 kg/d.METHODS: The study is based on the Copenhagen Airport Cohort, a historical cohort of male baggage handlers and a reference group of unskilled men from the greater Copenhagen area, followed from 1990 to 2012. Cumulative years of employment as a baggage handler was based on information from company employment and union registers. Outcome was first hospital admission with a discharge diagnosis of knee osteoarthritis and/or knee replacement, ascertained from the Danish National Patient Register.RESULTS: The cohort contained 3442 baggage handlers and 65 511 workers in the reference group. The unadjusted incidence rate ratio (IRR) of knee osteoarthritis increased steeply with cumulative years as a baggage handler. Although the exposure-response pattern became weaker and statistically nonsignificant (P ≈ .10) when adjusting for age, the risk of knee osteoarthritis was still increased in baggage handlers at the highest exposure level. Additional analyses showed that the association between age and osteoarthritis was stronger for baggage handlers (IRR = 2.09; 95% CI: 1.68-2.60) than for referents (IRR = 1.58; 95% CI: 1.53-1.63), indicating that knee osteoarthritis occurred at a younger age among baggage handlers than in the reference group.CONCLUSIONS: The results of this prospective cohort study support that long-term heavy lifting increases the risk of knee osteoarthritis.

AB - BACKGROUND: Knee osteoarthritis is a common and often disabling disorder, which has been related to knee-straining work. However, exposure response relations are uncertain and there are few prospective studies. We studied prospectively if incident knee osteoarthritis is associated with cumulative exposure as an airport baggage handler, lifting on average 5000 kg/d.METHODS: The study is based on the Copenhagen Airport Cohort, a historical cohort of male baggage handlers and a reference group of unskilled men from the greater Copenhagen area, followed from 1990 to 2012. Cumulative years of employment as a baggage handler was based on information from company employment and union registers. Outcome was first hospital admission with a discharge diagnosis of knee osteoarthritis and/or knee replacement, ascertained from the Danish National Patient Register.RESULTS: The cohort contained 3442 baggage handlers and 65 511 workers in the reference group. The unadjusted incidence rate ratio (IRR) of knee osteoarthritis increased steeply with cumulative years as a baggage handler. Although the exposure-response pattern became weaker and statistically nonsignificant (P ≈ .10) when adjusting for age, the risk of knee osteoarthritis was still increased in baggage handlers at the highest exposure level. Additional analyses showed that the association between age and osteoarthritis was stronger for baggage handlers (IRR = 2.09; 95% CI: 1.68-2.60) than for referents (IRR = 1.58; 95% CI: 1.53-1.63), indicating that knee osteoarthritis occurred at a younger age among baggage handlers than in the reference group.CONCLUSIONS: The results of this prospective cohort study support that long-term heavy lifting increases the risk of knee osteoarthritis.

U2 - 10.1002/ajim.23044

DO - 10.1002/ajim.23044

M3 - Journal article

VL - 62

SP - 951

EP - 960

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

SN - 0271-3586

IS - 11

ER -

ID: 226528264