Influence of age on leptin induced skeletal muscle signaling

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Standard

Influence of age on leptin induced skeletal muscle signaling. / Guadalupe Grau, Amelia; Larsen, Steen; Guerra, Borja; Calbet, Jose Al; Dela, Flemming; Helge, Jørn Wulff.

I: Acta Physiologica, Bind 211, Nr. 1, 08.03.2014, s. 214-228.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Guadalupe Grau, A, Larsen, S, Guerra, B, Calbet, JA, Dela, F & Helge, JW 2014, 'Influence of age on leptin induced skeletal muscle signaling', Acta Physiologica, bind 211, nr. 1, s. 214-228. https://doi.org/10.1111/apha.12273

APA

Guadalupe Grau, A., Larsen, S., Guerra, B., Calbet, J. A., Dela, F., & Helge, J. W. (2014). Influence of age on leptin induced skeletal muscle signaling. Acta Physiologica, 211(1), 214-228. https://doi.org/10.1111/apha.12273

Vancouver

Guadalupe Grau A, Larsen S, Guerra B, Calbet JA, Dela F, Helge JW. Influence of age on leptin induced skeletal muscle signaling. Acta Physiologica. 2014 mar 8;211(1):214-228. https://doi.org/10.1111/apha.12273

Author

Guadalupe Grau, Amelia ; Larsen, Steen ; Guerra, Borja ; Calbet, Jose Al ; Dela, Flemming ; Helge, Jørn Wulff. / Influence of age on leptin induced skeletal muscle signaling. I: Acta Physiologica. 2014 ; Bind 211, Nr. 1. s. 214-228.

Bibtex

@article{685ae3f1549b4f449e6ffdbd2b1cd00f,
title = "Influence of age on leptin induced skeletal muscle signaling",
abstract = "Age associated fat mass accumulation could be due to dysregulation of leptin signaling in skeletal muscle. Thus, we investigated total protein expression and phosphorylation levels of the long isoform of the leptin receptor (OB-Rb), and leptin signaling through Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3), insulin receptor substrate 1 (IRS-1), AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC), combined with the leptin signaling inhibitors suppressor of cytokine signaling 3 (SOCS3) and protein tyrosine phosphatase 1B (PTP1B) in human skeletal muscle of different age.",
author = "{Guadalupe Grau}, Amelia and Steen Larsen and Borja Guerra and Calbet, {Jose Al} and Flemming Dela and Helge, {J{\o}rn Wulff}",
note = "This article is protected by copyright. All rights reserved.",
year = "2014",
month = mar,
day = "8",
doi = "10.1111/apha.12273",
language = "English",
volume = "211",
pages = "214--228",
journal = "Acta Physiologica (Print)",
issn = "1748-1708",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Influence of age on leptin induced skeletal muscle signaling

AU - Guadalupe Grau, Amelia

AU - Larsen, Steen

AU - Guerra, Borja

AU - Calbet, Jose Al

AU - Dela, Flemming

AU - Helge, Jørn Wulff

N1 - This article is protected by copyright. All rights reserved.

PY - 2014/3/8

Y1 - 2014/3/8

N2 - Age associated fat mass accumulation could be due to dysregulation of leptin signaling in skeletal muscle. Thus, we investigated total protein expression and phosphorylation levels of the long isoform of the leptin receptor (OB-Rb), and leptin signaling through Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3), insulin receptor substrate 1 (IRS-1), AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC), combined with the leptin signaling inhibitors suppressor of cytokine signaling 3 (SOCS3) and protein tyrosine phosphatase 1B (PTP1B) in human skeletal muscle of different age.

AB - Age associated fat mass accumulation could be due to dysregulation of leptin signaling in skeletal muscle. Thus, we investigated total protein expression and phosphorylation levels of the long isoform of the leptin receptor (OB-Rb), and leptin signaling through Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3), insulin receptor substrate 1 (IRS-1), AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC), combined with the leptin signaling inhibitors suppressor of cytokine signaling 3 (SOCS3) and protein tyrosine phosphatase 1B (PTP1B) in human skeletal muscle of different age.

U2 - 10.1111/apha.12273

DO - 10.1111/apha.12273

M3 - Journal article

C2 - 24605926

VL - 211

SP - 214

EP - 228

JO - Acta Physiologica (Print)

JF - Acta Physiologica (Print)

SN - 1748-1708

IS - 1

ER -

ID: 106713364