High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers

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Standard

High tumor uptake of (64)Cu : implications for molecular imaging of tumor characteristics with copper-based PET tracers. / Jørgensen, Jesper Tranekjær; Persson, Morten; Madsen, Jacob; Kjær, Andreas.

I: Nuclear Medicine and Biology, Bind 40, Nr. 3, 04.2013, s. 345-50.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Jørgensen, JT, Persson, M, Madsen, J & Kjær, A 2013, 'High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers', Nuclear Medicine and Biology, bind 40, nr. 3, s. 345-50. https://doi.org/10.1016/j.nucmedbio.2013.01.002

APA

Jørgensen, J. T., Persson, M., Madsen, J., & Kjær, A. (2013). High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers. Nuclear Medicine and Biology, 40(3), 345-50. https://doi.org/10.1016/j.nucmedbio.2013.01.002

Vancouver

Jørgensen JT, Persson M, Madsen J, Kjær A. High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers. Nuclear Medicine and Biology. 2013 apr;40(3):345-50. https://doi.org/10.1016/j.nucmedbio.2013.01.002

Author

Jørgensen, Jesper Tranekjær ; Persson, Morten ; Madsen, Jacob ; Kjær, Andreas. / High tumor uptake of (64)Cu : implications for molecular imaging of tumor characteristics with copper-based PET tracers. I: Nuclear Medicine and Biology. 2013 ; Bind 40, Nr. 3. s. 345-50.

Bibtex

@article{d73ad73a64a84618a1211bb953276647,
title = "High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers",
abstract = "The use of copper-based positron emission tomography (PET) tracers in cancer studies is increasing. However, as copper has previously been found in high concentrations in human tumor tissue in vivo, instability of PET tracers could result in tumor accumulation of non-tracer-bound radioactive copper that may influence PET measurements. Here we determine the degree of (64)Cu uptake in five commonly used human cancer xenograft models in mice. Additionally, we compare copper accumulation in tumor tissue to gene expression of human copper transporter 1 (CTR1).",
author = "J{\o}rgensen, {Jesper Tranekj{\ae}r} and Morten Persson and Jacob Madsen and Andreas Kj{\ae}r",
note = "Copyright {\circledC} 2013 Elsevier Inc. All rights reserved.",
year = "2013",
month = "4",
doi = "10.1016/j.nucmedbio.2013.01.002",
language = "English",
volume = "40",
pages = "345--50",
journal = "Nuclear Medicine and Biology",
issn = "0969-8051",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - High tumor uptake of (64)Cu

T2 - implications for molecular imaging of tumor characteristics with copper-based PET tracers

AU - Jørgensen, Jesper Tranekjær

AU - Persson, Morten

AU - Madsen, Jacob

AU - Kjær, Andreas

N1 - Copyright © 2013 Elsevier Inc. All rights reserved.

PY - 2013/4

Y1 - 2013/4

N2 - The use of copper-based positron emission tomography (PET) tracers in cancer studies is increasing. However, as copper has previously been found in high concentrations in human tumor tissue in vivo, instability of PET tracers could result in tumor accumulation of non-tracer-bound radioactive copper that may influence PET measurements. Here we determine the degree of (64)Cu uptake in five commonly used human cancer xenograft models in mice. Additionally, we compare copper accumulation in tumor tissue to gene expression of human copper transporter 1 (CTR1).

AB - The use of copper-based positron emission tomography (PET) tracers in cancer studies is increasing. However, as copper has previously been found in high concentrations in human tumor tissue in vivo, instability of PET tracers could result in tumor accumulation of non-tracer-bound radioactive copper that may influence PET measurements. Here we determine the degree of (64)Cu uptake in five commonly used human cancer xenograft models in mice. Additionally, we compare copper accumulation in tumor tissue to gene expression of human copper transporter 1 (CTR1).

U2 - 10.1016/j.nucmedbio.2013.01.002

DO - 10.1016/j.nucmedbio.2013.01.002

M3 - Journal article

C2 - 23394821

VL - 40

SP - 345

EP - 350

JO - Nuclear Medicine and Biology

JF - Nuclear Medicine and Biology

SN - 0969-8051

IS - 3

ER -

ID: 45845300