Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men

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Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men. / Rosenkilde, M; Nordby, P; Nielsen, L B; Stallknecht, B M; Helge, J W.

I: International Journal of Obesity, Bind 34, Nr. 5, 2010, s. 871-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rosenkilde, M, Nordby, P, Nielsen, LB, Stallknecht, BM & Helge, JW 2010, 'Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men', International Journal of Obesity, bind 34, nr. 5, s. 871-7. https://doi.org/10.1038/ijo.2010.11

APA

Rosenkilde, M., Nordby, P., Nielsen, L. B., Stallknecht, B. M., & Helge, J. W. (2010). Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men. International Journal of Obesity, 34(5), 871-7. https://doi.org/10.1038/ijo.2010.11

Vancouver

Rosenkilde M, Nordby P, Nielsen LB, Stallknecht BM, Helge JW. Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men. International Journal of Obesity. 2010;34(5):871-7. https://doi.org/10.1038/ijo.2010.11

Author

Rosenkilde, M ; Nordby, P ; Nielsen, L B ; Stallknecht, B M ; Helge, J W. / Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men. I: International Journal of Obesity. 2010 ; Bind 34, Nr. 5. s. 871-7.

Bibtex

@article{34ed59806d4711df928f000ea68e967b,
title = "Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men",
abstract = "OBJECTIVE: To elucidate if fat oxidation at rest predicts peak fat oxidation during exercise and/or metabolic phenotype in moderately overweight, sedentary men. DESIGN: Cross-sectional study.Subjects:We measured respiratory exchange ratio (RER) at rest in 44 moderately overweight, normotensive and normoglycemic men and selected 8 subjects with a low RER (L-RER, body mass index (BMI): 27.9+/-0.9 kg m(-2), RER: 0.76+/-0.02) and 8 with a high RER (H-RER; BMI 28.1+/-1.1 kg m(-2), RER: 0.89+/-0.02). After an overnight fast, a venous blood sample was obtained and a graded exercise test was performed. Fat oxidation during exercise was quantified using indirect calorimetry. RESULTS: Peak fat oxidation during exercise was higher in L-RER than in H-RER (0.333+/-0.096 vs 0.169+/-0.028 g min(-1); P<0.01) and occurred at a higher relative intensity (36.2+/-6.6 vs 28.2+/-3.1% VO(2max), P<0.05). Using the International Diabetes Federation criteria, we found that there was a lower accumulation of metabolic risk factors in L-RER than in H-RER (1.6 vs 3.5, P=0.028), and no subjects in L-RER and four of eight subjects in H-RER had the metabolic syndrome. Resting RER was positively correlated with plasma triglycerides (P<0.01) and negatively with plasma free fatty acids (P<0.05), and peak fat oxidation during exercise was positively correlated with plasma free fatty acid concentration at rest (P<0.05). CONCLUSION: A low RER at rest predicts a high peak fat oxidation during exercise and a healthy metabolic phenotype in moderately overweight, sedentary men.",
author = "M Rosenkilde and P Nordby and Nielsen, {L B} and Stallknecht, {B M} and Helge, {J W}",
year = "2010",
doi = "10.1038/ijo.2010.11",
language = "English",
volume = "34",
pages = "871--7",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "5",

}

RIS

TY - JOUR

T1 - Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men

AU - Rosenkilde, M

AU - Nordby, P

AU - Nielsen, L B

AU - Stallknecht, B M

AU - Helge, J W

PY - 2010

Y1 - 2010

N2 - OBJECTIVE: To elucidate if fat oxidation at rest predicts peak fat oxidation during exercise and/or metabolic phenotype in moderately overweight, sedentary men. DESIGN: Cross-sectional study.Subjects:We measured respiratory exchange ratio (RER) at rest in 44 moderately overweight, normotensive and normoglycemic men and selected 8 subjects with a low RER (L-RER, body mass index (BMI): 27.9+/-0.9 kg m(-2), RER: 0.76+/-0.02) and 8 with a high RER (H-RER; BMI 28.1+/-1.1 kg m(-2), RER: 0.89+/-0.02). After an overnight fast, a venous blood sample was obtained and a graded exercise test was performed. Fat oxidation during exercise was quantified using indirect calorimetry. RESULTS: Peak fat oxidation during exercise was higher in L-RER than in H-RER (0.333+/-0.096 vs 0.169+/-0.028 g min(-1); P<0.01) and occurred at a higher relative intensity (36.2+/-6.6 vs 28.2+/-3.1% VO(2max), P<0.05). Using the International Diabetes Federation criteria, we found that there was a lower accumulation of metabolic risk factors in L-RER than in H-RER (1.6 vs 3.5, P=0.028), and no subjects in L-RER and four of eight subjects in H-RER had the metabolic syndrome. Resting RER was positively correlated with plasma triglycerides (P<0.01) and negatively with plasma free fatty acids (P<0.05), and peak fat oxidation during exercise was positively correlated with plasma free fatty acid concentration at rest (P<0.05). CONCLUSION: A low RER at rest predicts a high peak fat oxidation during exercise and a healthy metabolic phenotype in moderately overweight, sedentary men.

AB - OBJECTIVE: To elucidate if fat oxidation at rest predicts peak fat oxidation during exercise and/or metabolic phenotype in moderately overweight, sedentary men. DESIGN: Cross-sectional study.Subjects:We measured respiratory exchange ratio (RER) at rest in 44 moderately overweight, normotensive and normoglycemic men and selected 8 subjects with a low RER (L-RER, body mass index (BMI): 27.9+/-0.9 kg m(-2), RER: 0.76+/-0.02) and 8 with a high RER (H-RER; BMI 28.1+/-1.1 kg m(-2), RER: 0.89+/-0.02). After an overnight fast, a venous blood sample was obtained and a graded exercise test was performed. Fat oxidation during exercise was quantified using indirect calorimetry. RESULTS: Peak fat oxidation during exercise was higher in L-RER than in H-RER (0.333+/-0.096 vs 0.169+/-0.028 g min(-1); P<0.01) and occurred at a higher relative intensity (36.2+/-6.6 vs 28.2+/-3.1% VO(2max), P<0.05). Using the International Diabetes Federation criteria, we found that there was a lower accumulation of metabolic risk factors in L-RER than in H-RER (1.6 vs 3.5, P=0.028), and no subjects in L-RER and four of eight subjects in H-RER had the metabolic syndrome. Resting RER was positively correlated with plasma triglycerides (P<0.01) and negatively with plasma free fatty acids (P<0.05), and peak fat oxidation during exercise was positively correlated with plasma free fatty acid concentration at rest (P<0.05). CONCLUSION: A low RER at rest predicts a high peak fat oxidation during exercise and a healthy metabolic phenotype in moderately overweight, sedentary men.

U2 - 10.1038/ijo.2010.11

DO - 10.1038/ijo.2010.11

M3 - Journal article

C2 - 20157319

VL - 34

SP - 871

EP - 877

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 5

ER -

ID: 20095749