Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

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Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial. / Uth, Jacob; Fristrup, Bjørn; Sørensen, Victor; Helge, Eva Wulff; Christensen, Maja Kjærgaard; Kjærgaard, Julie Boye; Møller, Trine Kjeldgaard Tang; Mohr, Magni; Helge, Jørn Wulff; Jørgensen, Niklas Rye; Rørth, Mikael; Vadstrup, Eva Soelberg; Krustrup, Peter.

I: Progress in Cardiovascular Diseases, Bind 63, Nr. 6, 2020, s. 792-799.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Uth, J, Fristrup, B, Sørensen, V, Helge, EW, Christensen, MK, Kjærgaard, JB, Møller, TKT, Mohr, M, Helge, JW, Jørgensen, NR, Rørth, M, Vadstrup, ES & Krustrup, P 2020, 'Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial', Progress in Cardiovascular Diseases, bind 63, nr. 6, s. 792-799. https://doi.org/10.1016/j.pcad.2020.08.002

APA

Uth, J., Fristrup, B., Sørensen, V., Helge, E. W., Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, J. W., Jørgensen, N. R., Rørth, M., Vadstrup, E. S., & Krustrup, P. (2020). Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial. Progress in Cardiovascular Diseases, 63(6), 792-799. https://doi.org/10.1016/j.pcad.2020.08.002

Vancouver

Uth J, Fristrup B, Sørensen V, Helge EW, Christensen MK, Kjærgaard JB o.a. Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial. Progress in Cardiovascular Diseases. 2020;63(6):792-799. https://doi.org/10.1016/j.pcad.2020.08.002

Author

Uth, Jacob ; Fristrup, Bjørn ; Sørensen, Victor ; Helge, Eva Wulff ; Christensen, Maja Kjærgaard ; Kjærgaard, Julie Boye ; Møller, Trine Kjeldgaard Tang ; Mohr, Magni ; Helge, Jørn Wulff ; Jørgensen, Niklas Rye ; Rørth, Mikael ; Vadstrup, Eva Soelberg ; Krustrup, Peter. / Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial. I: Progress in Cardiovascular Diseases. 2020 ; Bind 63, Nr. 6. s. 792-799.

Bibtex

@article{79ff954fd2414e3b915dbdbc62b4e967,
title = "Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial",
abstract = "Purpose: To examine the exercise intensity and impact of 12 months of twice-weekly recreational football training on cardiorespiratory fitness (CRF), blood pressure (BP), resting heart rate (HRrest), body fat mass, blood lipids, inflammation, and health-related quality of life in women treated for early-stage breast cancer (BC).Methods: Sixty-eight women who had received surgery for stage I-III BC and completed adjuvant chemo- and/or radiation therapy within 5 years were randomized in a 2:1 ratio to a Football Fitness group (FFG, n = 46) or a control group (CON, n = 22). Football Fitness sessions comprised a warm-up, drills and 3-4 × 7 min of small-sided games (SSG). Assessments were performed at baseline, 6 months and 12 months. Outcomes were peak oxygen uptake (VO2peak), blood pressure (BP), HRrest, total body fat mass, and circulating plasma lipids and hs-CRP, and the 36-Item Short Form Health Survey (SF36). Intention-to-treat (ITT) analyses were performed using linear mixed models. Data are means with SD or 95% confidence intervals.Results: Adherence to training in participants completing the 12-months follow-up (n = 33) was 47.1% (22.7), and HR during SSG was ≥80% of HRmax for 69.8% (26.5) of total playing time. At baseline, VO2peak was 28.5 (6.4) and 25.6 (5.9) ml O2/kg/min in FFG and CON, respectively, and no significant changes were observed at 6- or 12 months follow-up. Systolic BP (SBP) was 117.1 (16.4) and 116.9 (14.8) mmHg, and diastolic BP (DBP) was 72.0 (11.2) and 72.4 (8.5) mmHg in FFG and CON, respectively, at baseline, and a 9.4 mmHg decrease in SBP in CON at 12 months resulted in a between-group difference at 12 months of 8.7 mmHg (p = .012). Blood lipids and hs-CRP were within the normal range at baseline, and there were no differences in changes between groups over the 12 months. Similarly, no differences between groups were observed in HRrest and body fat mass at 6- and 12-months follow-up. A between-group difference in mean changes of 23.5 (0.95-46.11) points in the role-physical domain of the SF36 survey favored FFG at 6 months. Conclusion: Football Fitness training is an intense exercise form for women treated for breast cancer, and self-perceived health-related limitations on daily activities were improved after 6 months. However, 1 year of Football Fitness training comprising 1 weekly training session on average did not improve CRF, BP, blood lipids, fat mass, or HRrest.Trial Registration Number: The trial was registered at ClinicalTrials.gov with identifier NCT03284567.",
keywords = "Faculty of Science, VO2max, Fitness, Breast cancer rehabilitation, Blood pressure, Blood lipids, Soccer",
author = "Jacob Uth and Bj{\o}rn Fristrup and Victor S{\o}rensen and Helge, {Eva Wulff} and Christensen, {Maja Kj{\ae}rgaard} and Kj{\ae}rgaard, {Julie Boye} and M{\o}ller, {Trine Kjeldgaard Tang} and Magni Mohr and Helge, {J{\o}rn Wulff} and J{\o}rgensen, {Niklas Rye} and Mikael R{\o}rth and Vadstrup, {Eva Soelberg} and Peter Krustrup",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Inc.",
year = "2020",
doi = "10.1016/j.pcad.2020.08.002",
language = "English",
volume = "63",
pages = "792--799",
journal = "Progress in Cardiovascular Diseases",
issn = "0033-0620",
publisher = "W.B.Saunders Co.",
number = "6",

}

RIS

TY - JOUR

T1 - Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

AU - Uth, Jacob

AU - Fristrup, Bjørn

AU - Sørensen, Victor

AU - Helge, Eva Wulff

AU - Christensen, Maja Kjærgaard

AU - Kjærgaard, Julie Boye

AU - Møller, Trine Kjeldgaard Tang

AU - Mohr, Magni

AU - Helge, Jørn Wulff

AU - Jørgensen, Niklas Rye

AU - Rørth, Mikael

AU - Vadstrup, Eva Soelberg

AU - Krustrup, Peter

N1 - Copyright © 2020. Published by Elsevier Inc.

PY - 2020

Y1 - 2020

N2 - Purpose: To examine the exercise intensity and impact of 12 months of twice-weekly recreational football training on cardiorespiratory fitness (CRF), blood pressure (BP), resting heart rate (HRrest), body fat mass, blood lipids, inflammation, and health-related quality of life in women treated for early-stage breast cancer (BC).Methods: Sixty-eight women who had received surgery for stage I-III BC and completed adjuvant chemo- and/or radiation therapy within 5 years were randomized in a 2:1 ratio to a Football Fitness group (FFG, n = 46) or a control group (CON, n = 22). Football Fitness sessions comprised a warm-up, drills and 3-4 × 7 min of small-sided games (SSG). Assessments were performed at baseline, 6 months and 12 months. Outcomes were peak oxygen uptake (VO2peak), blood pressure (BP), HRrest, total body fat mass, and circulating plasma lipids and hs-CRP, and the 36-Item Short Form Health Survey (SF36). Intention-to-treat (ITT) analyses were performed using linear mixed models. Data are means with SD or 95% confidence intervals.Results: Adherence to training in participants completing the 12-months follow-up (n = 33) was 47.1% (22.7), and HR during SSG was ≥80% of HRmax for 69.8% (26.5) of total playing time. At baseline, VO2peak was 28.5 (6.4) and 25.6 (5.9) ml O2/kg/min in FFG and CON, respectively, and no significant changes were observed at 6- or 12 months follow-up. Systolic BP (SBP) was 117.1 (16.4) and 116.9 (14.8) mmHg, and diastolic BP (DBP) was 72.0 (11.2) and 72.4 (8.5) mmHg in FFG and CON, respectively, at baseline, and a 9.4 mmHg decrease in SBP in CON at 12 months resulted in a between-group difference at 12 months of 8.7 mmHg (p = .012). Blood lipids and hs-CRP were within the normal range at baseline, and there were no differences in changes between groups over the 12 months. Similarly, no differences between groups were observed in HRrest and body fat mass at 6- and 12-months follow-up. A between-group difference in mean changes of 23.5 (0.95-46.11) points in the role-physical domain of the SF36 survey favored FFG at 6 months. Conclusion: Football Fitness training is an intense exercise form for women treated for breast cancer, and self-perceived health-related limitations on daily activities were improved after 6 months. However, 1 year of Football Fitness training comprising 1 weekly training session on average did not improve CRF, BP, blood lipids, fat mass, or HRrest.Trial Registration Number: The trial was registered at ClinicalTrials.gov with identifier NCT03284567.

AB - Purpose: To examine the exercise intensity and impact of 12 months of twice-weekly recreational football training on cardiorespiratory fitness (CRF), blood pressure (BP), resting heart rate (HRrest), body fat mass, blood lipids, inflammation, and health-related quality of life in women treated for early-stage breast cancer (BC).Methods: Sixty-eight women who had received surgery for stage I-III BC and completed adjuvant chemo- and/or radiation therapy within 5 years were randomized in a 2:1 ratio to a Football Fitness group (FFG, n = 46) or a control group (CON, n = 22). Football Fitness sessions comprised a warm-up, drills and 3-4 × 7 min of small-sided games (SSG). Assessments were performed at baseline, 6 months and 12 months. Outcomes were peak oxygen uptake (VO2peak), blood pressure (BP), HRrest, total body fat mass, and circulating plasma lipids and hs-CRP, and the 36-Item Short Form Health Survey (SF36). Intention-to-treat (ITT) analyses were performed using linear mixed models. Data are means with SD or 95% confidence intervals.Results: Adherence to training in participants completing the 12-months follow-up (n = 33) was 47.1% (22.7), and HR during SSG was ≥80% of HRmax for 69.8% (26.5) of total playing time. At baseline, VO2peak was 28.5 (6.4) and 25.6 (5.9) ml O2/kg/min in FFG and CON, respectively, and no significant changes were observed at 6- or 12 months follow-up. Systolic BP (SBP) was 117.1 (16.4) and 116.9 (14.8) mmHg, and diastolic BP (DBP) was 72.0 (11.2) and 72.4 (8.5) mmHg in FFG and CON, respectively, at baseline, and a 9.4 mmHg decrease in SBP in CON at 12 months resulted in a between-group difference at 12 months of 8.7 mmHg (p = .012). Blood lipids and hs-CRP were within the normal range at baseline, and there were no differences in changes between groups over the 12 months. Similarly, no differences between groups were observed in HRrest and body fat mass at 6- and 12-months follow-up. A between-group difference in mean changes of 23.5 (0.95-46.11) points in the role-physical domain of the SF36 survey favored FFG at 6 months. Conclusion: Football Fitness training is an intense exercise form for women treated for breast cancer, and self-perceived health-related limitations on daily activities were improved after 6 months. However, 1 year of Football Fitness training comprising 1 weekly training session on average did not improve CRF, BP, blood lipids, fat mass, or HRrest.Trial Registration Number: The trial was registered at ClinicalTrials.gov with identifier NCT03284567.

KW - Faculty of Science

KW - VO2max

KW - Fitness

KW - Breast cancer rehabilitation

KW - Blood pressure

KW - Blood lipids

KW - Soccer

U2 - 10.1016/j.pcad.2020.08.002

DO - 10.1016/j.pcad.2020.08.002

M3 - Journal article

C2 - 32800792

VL - 63

SP - 792

EP - 799

JO - Progress in Cardiovascular Diseases

JF - Progress in Cardiovascular Diseases

SN - 0033-0620

IS - 6

ER -

ID: 247385049