C-type natriuretic-derived peptides as biomarkers in human disease

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Solvej Kølvraa Lippert, Jens Peter Goetze

The natriuretic peptide system comprises three structurally related peptides: atrial natriuretic peptide, B-type natriuretic peptide and C-type natriuretic peptide. In circulation, they play an important endocrine role in the regulation of cardiovascular homeostasis by maintaining blood pressure and extracellular fluid volume. Atrial natriuretic peptide and B-type natriuretic peptide have gained considerable diagnostic interest as biomarkers in cardiovascular disease. By contrast, C-type natriuretic peptide has not yet been ascribed a role in human diagnostics. This perspective aims at recapitulating the present biochemical and clinical issues concerning C-type natriuretic peptide measurement in plasma as a potential biomarker.
OriginalsprogEngelsk
TidsskriftBiomarkers in Medicine
Vol/bind4
Udgave nummer4
Sider (fra-til)631-9
Antal sider9
ISSN1752-0363
DOI
StatusUdgivet - 1 aug. 2010

ID: 34132113