“Chronic urticaria and obstructive sleep apnea: Is there a significant association?”

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

“Chronic urticaria and obstructive sleep apnea : Is there a significant association?”. / Cherrez-Ojeda, Ivan; Maurer, Marcus; Felix, Miguel; Bernstein, Jonathan A.; Ramon, German D.; Jardim Criado, Roberta Fachini; Mata, Valeria L.; Cherrez, Annia; Morfin-Maciel, Blanca María; Larco, José Ignacio; Tinoco, Iván O.; Chorzepa, Gonzalo Federico; Gómez, René Maximiliano; Raad, Rodolfo Jaller; Thomsen, Simon Francis; Schmid-Grendelmeier, Peter; Guillet, Carole; Cherrez, Sofia; Vanegas, Emanuel.

I: World Allergy Organization Journal, Bind 14, Nr. 8, 100577, 2021.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Cherrez-Ojeda, I, Maurer, M, Felix, M, Bernstein, JA, Ramon, GD, Jardim Criado, RF, Mata, VL, Cherrez, A, Morfin-Maciel, BM, Larco, JI, Tinoco, IO, Chorzepa, GF, Gómez, RM, Raad, RJ, Thomsen, SF, Schmid-Grendelmeier, P, Guillet, C, Cherrez, S & Vanegas, E 2021, '“Chronic urticaria and obstructive sleep apnea: Is there a significant association?”', World Allergy Organization Journal, bind 14, nr. 8, 100577. https://doi.org/10.1016/j.waojou.2021.100577

APA

Cherrez-Ojeda, I., Maurer, M., Felix, M., Bernstein, J. A., Ramon, G. D., Jardim Criado, R. F., Mata, V. L., Cherrez, A., Morfin-Maciel, B. M., Larco, J. I., Tinoco, I. O., Chorzepa, G. F., Gómez, R. M., Raad, R. J., Thomsen, S. F., Schmid-Grendelmeier, P., Guillet, C., Cherrez, S., & Vanegas, E. (2021). “Chronic urticaria and obstructive sleep apnea: Is there a significant association?”. World Allergy Organization Journal, 14(8), [100577]. https://doi.org/10.1016/j.waojou.2021.100577

Vancouver

Cherrez-Ojeda I, Maurer M, Felix M, Bernstein JA, Ramon GD, Jardim Criado RF o.a. “Chronic urticaria and obstructive sleep apnea: Is there a significant association?”. World Allergy Organization Journal. 2021;14(8). 100577. https://doi.org/10.1016/j.waojou.2021.100577

Author

Cherrez-Ojeda, Ivan ; Maurer, Marcus ; Felix, Miguel ; Bernstein, Jonathan A. ; Ramon, German D. ; Jardim Criado, Roberta Fachini ; Mata, Valeria L. ; Cherrez, Annia ; Morfin-Maciel, Blanca María ; Larco, José Ignacio ; Tinoco, Iván O. ; Chorzepa, Gonzalo Federico ; Gómez, René Maximiliano ; Raad, Rodolfo Jaller ; Thomsen, Simon Francis ; Schmid-Grendelmeier, Peter ; Guillet, Carole ; Cherrez, Sofia ; Vanegas, Emanuel. / “Chronic urticaria and obstructive sleep apnea : Is there a significant association?”. I: World Allergy Organization Journal. 2021 ; Bind 14, Nr. 8.

Bibtex

@article{3e82652fce5848aaa54b58d156bb52b5,
title = "“Chronic urticaria and obstructive sleep apnea: Is there a significant association?”",
abstract = "Background: Few studies have explored the association between obstructive sleep apnea (OSA) and chronic urticaria (CU). Our study aims to fill this gap by determining the frequency of the risk categories for OSA and how they might correlate with the specific CU patient reported outcome measures urticaria activity score (UAS7), urticaria control test (UCT) and CU quality of life questionnaire (CU-Q2oL). Methods: We conducted a cross-sectional study involving a cohort of 171 Latin American CU patients. Descriptive statistics were used to determine frequency and proportions for demographic and clinical variables, while a chi-squared test for association between STOP-Bang OSA questionnaire categories and both UAS7 and UCT categories was performed to analyze how such variables interact. To further assess the strength of the correlation a Cramer's V coefficient was reported. Finally, a Kendall-Tau b correlation coefficient was performed to measure the correlation between the STOP-Bang score and other independent continuous variables. Results: The average STOP-Bang score was 2.5, with 24% and 21% of patients falling into the intermediate and high-risk category for moderate-to-severe OSA, respectively. There was a strong statistically significant association (Cramer's V = 0.263; p = .000) between UAS-7 categories and STOP-Bang risk categories. A similar pattern of strong significant association (Cramer's V = .269; p = .002) was observed between UCT categories and STOP-Bang risk categories. A weak positive correlation between the STOP-Bang score and the CU-Q2oL average score (τb = 0.188, p = .001) was identified. Overall, 72.5% patients reported limitations with respect to sleep in a varied degree according to the CU-Q2oL. Conclusions: Our results suggest that a considerable proportion of patients with CU are at intermediate to high risk for OSA. Higher disease activity, poor CU control, and worse quality of life were all found to be associated with an increased risk. Additional studies are needed to determine the exact link between these conditions, and to determine whether screening and treatment for OSA might benefit patients with CU.",
keywords = "Chronic urticaria, Quality of life, Sleep apnea",
author = "Ivan Cherrez-Ojeda and Marcus Maurer and Miguel Felix and Bernstein, {Jonathan A.} and Ramon, {German D.} and {Jardim Criado}, {Roberta Fachini} and Mata, {Valeria L.} and Annia Cherrez and Morfin-Maciel, {Blanca Mar{\'i}a} and Larco, {Jos{\'e} Ignacio} and Tinoco, {Iv{\'a}n O.} and Chorzepa, {Gonzalo Federico} and G{\'o}mez, {Ren{\'e} Maximiliano} and Raad, {Rodolfo Jaller} and Thomsen, {Simon Francis} and Peter Schmid-Grendelmeier and Carole Guillet and Sofia Cherrez and Emanuel Vanegas",
note = "Publisher Copyright: {\textcopyright} 2021 The Author(s)",
year = "2021",
doi = "10.1016/j.waojou.2021.100577",
language = "English",
volume = "14",
journal = "The World Allergy Organization Journal",
issn = "1939-4551",
publisher = "BioMed Central Ltd.",
number = "8",

}

RIS

TY - JOUR

T1 - “Chronic urticaria and obstructive sleep apnea

T2 - Is there a significant association?”

AU - Cherrez-Ojeda, Ivan

AU - Maurer, Marcus

AU - Felix, Miguel

AU - Bernstein, Jonathan A.

AU - Ramon, German D.

AU - Jardim Criado, Roberta Fachini

AU - Mata, Valeria L.

AU - Cherrez, Annia

AU - Morfin-Maciel, Blanca María

AU - Larco, José Ignacio

AU - Tinoco, Iván O.

AU - Chorzepa, Gonzalo Federico

AU - Gómez, René Maximiliano

AU - Raad, Rodolfo Jaller

AU - Thomsen, Simon Francis

AU - Schmid-Grendelmeier, Peter

AU - Guillet, Carole

AU - Cherrez, Sofia

AU - Vanegas, Emanuel

N1 - Publisher Copyright: © 2021 The Author(s)

PY - 2021

Y1 - 2021

N2 - Background: Few studies have explored the association between obstructive sleep apnea (OSA) and chronic urticaria (CU). Our study aims to fill this gap by determining the frequency of the risk categories for OSA and how they might correlate with the specific CU patient reported outcome measures urticaria activity score (UAS7), urticaria control test (UCT) and CU quality of life questionnaire (CU-Q2oL). Methods: We conducted a cross-sectional study involving a cohort of 171 Latin American CU patients. Descriptive statistics were used to determine frequency and proportions for demographic and clinical variables, while a chi-squared test for association between STOP-Bang OSA questionnaire categories and both UAS7 and UCT categories was performed to analyze how such variables interact. To further assess the strength of the correlation a Cramer's V coefficient was reported. Finally, a Kendall-Tau b correlation coefficient was performed to measure the correlation between the STOP-Bang score and other independent continuous variables. Results: The average STOP-Bang score was 2.5, with 24% and 21% of patients falling into the intermediate and high-risk category for moderate-to-severe OSA, respectively. There was a strong statistically significant association (Cramer's V = 0.263; p = .000) between UAS-7 categories and STOP-Bang risk categories. A similar pattern of strong significant association (Cramer's V = .269; p = .002) was observed between UCT categories and STOP-Bang risk categories. A weak positive correlation between the STOP-Bang score and the CU-Q2oL average score (τb = 0.188, p = .001) was identified. Overall, 72.5% patients reported limitations with respect to sleep in a varied degree according to the CU-Q2oL. Conclusions: Our results suggest that a considerable proportion of patients with CU are at intermediate to high risk for OSA. Higher disease activity, poor CU control, and worse quality of life were all found to be associated with an increased risk. Additional studies are needed to determine the exact link between these conditions, and to determine whether screening and treatment for OSA might benefit patients with CU.

AB - Background: Few studies have explored the association between obstructive sleep apnea (OSA) and chronic urticaria (CU). Our study aims to fill this gap by determining the frequency of the risk categories for OSA and how they might correlate with the specific CU patient reported outcome measures urticaria activity score (UAS7), urticaria control test (UCT) and CU quality of life questionnaire (CU-Q2oL). Methods: We conducted a cross-sectional study involving a cohort of 171 Latin American CU patients. Descriptive statistics were used to determine frequency and proportions for demographic and clinical variables, while a chi-squared test for association between STOP-Bang OSA questionnaire categories and both UAS7 and UCT categories was performed to analyze how such variables interact. To further assess the strength of the correlation a Cramer's V coefficient was reported. Finally, a Kendall-Tau b correlation coefficient was performed to measure the correlation between the STOP-Bang score and other independent continuous variables. Results: The average STOP-Bang score was 2.5, with 24% and 21% of patients falling into the intermediate and high-risk category for moderate-to-severe OSA, respectively. There was a strong statistically significant association (Cramer's V = 0.263; p = .000) between UAS-7 categories and STOP-Bang risk categories. A similar pattern of strong significant association (Cramer's V = .269; p = .002) was observed between UCT categories and STOP-Bang risk categories. A weak positive correlation between the STOP-Bang score and the CU-Q2oL average score (τb = 0.188, p = .001) was identified. Overall, 72.5% patients reported limitations with respect to sleep in a varied degree according to the CU-Q2oL. Conclusions: Our results suggest that a considerable proportion of patients with CU are at intermediate to high risk for OSA. Higher disease activity, poor CU control, and worse quality of life were all found to be associated with an increased risk. Additional studies are needed to determine the exact link between these conditions, and to determine whether screening and treatment for OSA might benefit patients with CU.

KW - Chronic urticaria

KW - Quality of life

KW - Sleep apnea

UR - http://www.scopus.com/inward/record.url?scp=85113378500&partnerID=8YFLogxK

U2 - 10.1016/j.waojou.2021.100577

DO - 10.1016/j.waojou.2021.100577

M3 - Journal article

C2 - 34471460

AN - SCOPUS:85113378500

VL - 14

JO - The World Allergy Organization Journal

JF - The World Allergy Organization Journal

SN - 1939-4551

IS - 8

M1 - 100577

ER -

ID: 281102103