Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome : a case control pilot study. / Hinterseer, Martin; Thomsen, Morten Bækgaard; Beckmann, Britt-Maria; Pfeufer, Arne; Schimpf, Rainer; Wichmann, H-Erich; Steinbeck, Gerhard; Vos, Marc A; Kaab, Stefan.

I: European Heart Journal, Bind 29, Nr. 2, 01.2008, s. 185-90.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Hinterseer, M, Thomsen, MB, Beckmann, B-M, Pfeufer, A, Schimpf, R, Wichmann, H-E, Steinbeck, G, Vos, MA & Kaab, S 2008, 'Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study', European Heart Journal, bind 29, nr. 2, s. 185-90. https://doi.org/10.1093/eurheartj/ehm586

APA

Hinterseer, M., Thomsen, M. B., Beckmann, B-M., Pfeufer, A., Schimpf, R., Wichmann, H-E., ... Kaab, S. (2008). Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study. European Heart Journal, 29(2), 185-90. https://doi.org/10.1093/eurheartj/ehm586

Vancouver

Hinterseer M, Thomsen MB, Beckmann B-M, Pfeufer A, Schimpf R, Wichmann H-E o.a. Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study. European Heart Journal. 2008 jan;29(2):185-90. https://doi.org/10.1093/eurheartj/ehm586

Author

Hinterseer, Martin ; Thomsen, Morten Bækgaard ; Beckmann, Britt-Maria ; Pfeufer, Arne ; Schimpf, Rainer ; Wichmann, H-Erich ; Steinbeck, Gerhard ; Vos, Marc A ; Kaab, Stefan. / Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome : a case control pilot study. I: European Heart Journal. 2008 ; Bind 29, Nr. 2. s. 185-90.

Bibtex

@article{c07befc1f2f849d799c4cbe0e2047e04,
title = "Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study",
abstract = "Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.",
keywords = "Aged, Arrhythmias, Cardiac, Case-Control Studies, Disease Susceptibility, Electrocardiography, Female, Heart Rate, Humans, Long QT Syndrome, Male, Middle Aged, Pilot Projects, Predictive Value of Tests, Torsades de Pointes",
author = "Martin Hinterseer and Thomsen, {Morten B{\ae}kgaard} and Britt-Maria Beckmann and Arne Pfeufer and Rainer Schimpf and H-Erich Wichmann and Gerhard Steinbeck and Vos, {Marc A} and Stefan Kaab",
year = "2008",
month = "1",
doi = "10.1093/eurheartj/ehm586",
language = "English",
volume = "29",
pages = "185--90",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome

T2 - a case control pilot study

AU - Hinterseer, Martin

AU - Thomsen, Morten Bækgaard

AU - Beckmann, Britt-Maria

AU - Pfeufer, Arne

AU - Schimpf, Rainer

AU - Wichmann, H-Erich

AU - Steinbeck, Gerhard

AU - Vos, Marc A

AU - Kaab, Stefan

PY - 2008/1

Y1 - 2008/1

N2 - Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.

AB - Torsades de pointes arrhythmias (TdP) occur by definition in the setting of prolonged QT intervals. Animal models of drug induced Long-QT syndrome (dLQTS) have shown higher predictive value for proarrhythmia with beat-to-beat variability of repolarization duration (BVR) when compared with QT intervals. Here, we evaluate variability of QT intervals in patients with a history of drug-induced long QT syndrome (dLQTS) and TdP in absence of a mutation in any of the major LQTS genes.

KW - Aged

KW - Arrhythmias, Cardiac

KW - Case-Control Studies

KW - Disease Susceptibility

KW - Electrocardiography

KW - Female

KW - Heart Rate

KW - Humans

KW - Long QT Syndrome

KW - Male

KW - Middle Aged

KW - Pilot Projects

KW - Predictive Value of Tests

KW - Torsades de Pointes

U2 - 10.1093/eurheartj/ehm586

DO - 10.1093/eurheartj/ehm586

M3 - Journal article

VL - 29

SP - 185

EP - 190

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 2

ER -

ID: 45965394