Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents

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Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents. / Tinggaard, Jeanette; Hagen, Casper P; Christensen, Anders N; Mouritsen, Annette; Mieritz, Mikkel G; Wohlfahrt-Veje, Christine; Helge, Jørn W; Beck, Thomas N; Fallentin, Eva; Larsen, Rasmus; Jensen, Rikke B; Juul, Anders; Main, Katharina M.

I: Pediatric Research, Bind 82, 2017, s. 620-628.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Tinggaard, J, Hagen, CP, Christensen, AN, Mouritsen, A, Mieritz, MG, Wohlfahrt-Veje, C, Helge, JW, Beck, TN, Fallentin, E, Larsen, R, Jensen, RB, Juul, A & Main, KM 2017, 'Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents', Pediatric Research, bind 82, s. 620-628. https://doi.org/10.1038/pr.2017.138

APA

Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., ... Main, K. M. (2017). Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents. Pediatric Research, 82, 620-628. https://doi.org/10.1038/pr.2017.138

Vancouver

Tinggaard J, Hagen CP, Christensen AN, Mouritsen A, Mieritz MG, Wohlfahrt-Veje C o.a. Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents. Pediatric Research. 2017;82:620-628. https://doi.org/10.1038/pr.2017.138

Author

Tinggaard, Jeanette ; Hagen, Casper P ; Christensen, Anders N ; Mouritsen, Annette ; Mieritz, Mikkel G ; Wohlfahrt-Veje, Christine ; Helge, Jørn W ; Beck, Thomas N ; Fallentin, Eva ; Larsen, Rasmus ; Jensen, Rikke B ; Juul, Anders ; Main, Katharina M. / Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents. I: Pediatric Research. 2017 ; Bind 82. s. 620-628.

Bibtex

@article{603a0d4c85474219bc5758248f29f78b,
title = "Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents",
abstract = "BACKGROUND: Abdominal fat distribution is associated with development of cardio-metabolic disease, independently of BMI. We assessed anthropometry, serum adipokines and DXA as markers of abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) by MRIMETHODS:We performed a cross-sectional study including 197 healthy adolescents (114 boys) aged 10-15 years nested within a longitudinal population-based cohort. Clinical examination, blood sampling, DXA and abdominal MRI was performed. SAT{\%} and VAT{\%} was adjusted to total abdominal volume.RESULTS: Girls had a higher SAT{\%} than boys in early and late puberty (16 vs. 13{\%}, P<0.01 and 20 vs. 15{\%}, P=0.001, respectively), whereas VAT{\%} was comparable (7{\%} in both genders, independent of puberty). DXA android fat{\%} (Standard Deviation Score [SDS]), suprailliac skinfold thickness (SDS), leptin, BMI (SDS), waist-to-height ratio (WHtR) and waist circumference (SDS) correlated strongly with SAT{\%} (descending order: r=0.90 to r=0.55, all P<0.001), but weaker to VAT{\%} (r=0.49 to r=0.06). Suprailiac skinfold was the best anthropometric marker of SAT{\%} (girls: R(2)=48.6{\%}, boys: R(2)=65.0{\%}, P<0.001) and VAT{\%} in boys (R(2)=16.4{\%}, P<0.001). WHtR was the best marker of VAT{\%} in girls (R(2)=7.6{\%}, P=0.007).CONCLUSIONS: Healthy girls have a higher SAT{\%} than boys, whereas VAT{\%} is comparable, independent of puberty. Anthropometry and circulating leptin are valid markers of SAT{\%}, but not VAT{\%}.Pediatric Research accepted article preview online, 12 June 2017. doi:10.1038/pr.2017.138.",
keywords = "Journal Article",
author = "Jeanette Tinggaard and Hagen, {Casper P} and Christensen, {Anders N} and Annette Mouritsen and Mieritz, {Mikkel G} and Christine Wohlfahrt-Veje and Helge, {J{\o}rn W} and Beck, {Thomas N} and Eva Fallentin and Rasmus Larsen and Jensen, {Rikke B} and Anders Juul and Main, {Katharina M}",
year = "2017",
doi = "10.1038/pr.2017.138",
language = "English",
volume = "82",
pages = "620--628",
journal = "Pediatric Research",
issn = "0031-3998",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents

AU - Tinggaard, Jeanette

AU - Hagen, Casper P

AU - Christensen, Anders N

AU - Mouritsen, Annette

AU - Mieritz, Mikkel G

AU - Wohlfahrt-Veje, Christine

AU - Helge, Jørn W

AU - Beck, Thomas N

AU - Fallentin, Eva

AU - Larsen, Rasmus

AU - Jensen, Rikke B

AU - Juul, Anders

AU - Main, Katharina M

PY - 2017

Y1 - 2017

N2 - BACKGROUND: Abdominal fat distribution is associated with development of cardio-metabolic disease, independently of BMI. We assessed anthropometry, serum adipokines and DXA as markers of abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) by MRIMETHODS:We performed a cross-sectional study including 197 healthy adolescents (114 boys) aged 10-15 years nested within a longitudinal population-based cohort. Clinical examination, blood sampling, DXA and abdominal MRI was performed. SAT% and VAT% was adjusted to total abdominal volume.RESULTS: Girls had a higher SAT% than boys in early and late puberty (16 vs. 13%, P<0.01 and 20 vs. 15%, P=0.001, respectively), whereas VAT% was comparable (7% in both genders, independent of puberty). DXA android fat% (Standard Deviation Score [SDS]), suprailliac skinfold thickness (SDS), leptin, BMI (SDS), waist-to-height ratio (WHtR) and waist circumference (SDS) correlated strongly with SAT% (descending order: r=0.90 to r=0.55, all P<0.001), but weaker to VAT% (r=0.49 to r=0.06). Suprailiac skinfold was the best anthropometric marker of SAT% (girls: R(2)=48.6%, boys: R(2)=65.0%, P<0.001) and VAT% in boys (R(2)=16.4%, P<0.001). WHtR was the best marker of VAT% in girls (R(2)=7.6%, P=0.007).CONCLUSIONS: Healthy girls have a higher SAT% than boys, whereas VAT% is comparable, independent of puberty. Anthropometry and circulating leptin are valid markers of SAT%, but not VAT%.Pediatric Research accepted article preview online, 12 June 2017. doi:10.1038/pr.2017.138.

AB - BACKGROUND: Abdominal fat distribution is associated with development of cardio-metabolic disease, independently of BMI. We assessed anthropometry, serum adipokines and DXA as markers of abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) by MRIMETHODS:We performed a cross-sectional study including 197 healthy adolescents (114 boys) aged 10-15 years nested within a longitudinal population-based cohort. Clinical examination, blood sampling, DXA and abdominal MRI was performed. SAT% and VAT% was adjusted to total abdominal volume.RESULTS: Girls had a higher SAT% than boys in early and late puberty (16 vs. 13%, P<0.01 and 20 vs. 15%, P=0.001, respectively), whereas VAT% was comparable (7% in both genders, independent of puberty). DXA android fat% (Standard Deviation Score [SDS]), suprailliac skinfold thickness (SDS), leptin, BMI (SDS), waist-to-height ratio (WHtR) and waist circumference (SDS) correlated strongly with SAT% (descending order: r=0.90 to r=0.55, all P<0.001), but weaker to VAT% (r=0.49 to r=0.06). Suprailiac skinfold was the best anthropometric marker of SAT% (girls: R(2)=48.6%, boys: R(2)=65.0%, P<0.001) and VAT% in boys (R(2)=16.4%, P<0.001). WHtR was the best marker of VAT% in girls (R(2)=7.6%, P=0.007).CONCLUSIONS: Healthy girls have a higher SAT% than boys, whereas VAT% is comparable, independent of puberty. Anthropometry and circulating leptin are valid markers of SAT%, but not VAT%.Pediatric Research accepted article preview online, 12 June 2017. doi:10.1038/pr.2017.138.

KW - Journal Article

U2 - 10.1038/pr.2017.138

DO - 10.1038/pr.2017.138

M3 - Journal article

C2 - 28604756

VL - 82

SP - 620

EP - 628

JO - Pediatric Research

JF - Pediatric Research

SN - 0031-3998

ER -

ID: 179406200