TY - JOUR

T1 - Adverse Metabolic Risk Profiles in Greenlandic Inuit Children Compared to Danish Children

AU - Munch-Andersen, T.

AU - Sorensen, K.

AU - Andersen, L. B.

AU - Aachmann-Andersen, N. J.

AU - Aksglaede, L.

AU - Juul, A.

AU - Helge, Jørn Wulff

PY - 2013/6

Y1 - 2013/6

N2 - ObjectiveDuring recent decades, the prevalence of metabolic morbidity has increased rapidly in adult Greenlandic Inuit. To what extent this is also reflected in the juvenile Inuit population is unknown. The objective was, therefore, in the comparison with Danish children, to evaluate metabolic profiles in Greenlandic Inuit children from the capital in the southern and from the northern most villagesDesign and Methods187 Inuit and 132 Danish children were examined with anthropometrics, pubertal staging, fasting blood samples, and a maximal aerobic test.ResultsBoth Inuit children living in Nuuk and the northern villages had significantly higher glucose, total cholesterol, apolipoprotein A1 levels, and diastolic blood pressure compared with Danish children after adjustment for differences in adiposity and aerobic fitness levels. The Inuit children living in Nuuk had significantly higher BMI, body fat %, HbA1c, and significantly lower aerobic fitness and ApoA1 levels than northern living Inuit children.ConclusionsGreenlandic Inuit children had adverse metabolic health profile compared to the Danish children, the differences where more pronounced in Inuit children living in Nuuk. The tendencies toward higher prevalence of diabetes and metabolic morbidity in the adult Greenlandic Inuit population may also be present in the Inuit children population.

AB - ObjectiveDuring recent decades, the prevalence of metabolic morbidity has increased rapidly in adult Greenlandic Inuit. To what extent this is also reflected in the juvenile Inuit population is unknown. The objective was, therefore, in the comparison with Danish children, to evaluate metabolic profiles in Greenlandic Inuit children from the capital in the southern and from the northern most villagesDesign and Methods187 Inuit and 132 Danish children were examined with anthropometrics, pubertal staging, fasting blood samples, and a maximal aerobic test.ResultsBoth Inuit children living in Nuuk and the northern villages had significantly higher glucose, total cholesterol, apolipoprotein A1 levels, and diastolic blood pressure compared with Danish children after adjustment for differences in adiposity and aerobic fitness levels. The Inuit children living in Nuuk had significantly higher BMI, body fat %, HbA1c, and significantly lower aerobic fitness and ApoA1 levels than northern living Inuit children.ConclusionsGreenlandic Inuit children had adverse metabolic health profile compared to the Danish children, the differences where more pronounced in Inuit children living in Nuuk. The tendencies toward higher prevalence of diabetes and metabolic morbidity in the adult Greenlandic Inuit population may also be present in the Inuit children population.

U2 - 10.1002/oby.20203

DO - 10.1002/oby.20203

M3 - Journal article

C2 - 23670907

VL - 21

SP - 1226

EP - 1231

JO - Obesity

JF - Obesity

SN - 1930-7381

IS - 6

ER -