Biosimulation and Functional Spectroscopy – University of Copenhagen

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Biosimulation and Functional Spectroscopy >

We combine innovative experimental techniques, new methods of data analysis and  mechanism-based modeling to bring new insights into functional interactions between the key components of cells, tissues and organs, as well as how these interactions change in diseases. With this,

  • we develop an  in vivo experimental approach based on Raman spectroscopic tools to study hemoglobin/cytochrome properties and signaling pathways in living erythrocytes, cardiomyocytes, isolated heart and brain slices;
  • we use the laser speckle flowmetry and advanced data analysis to evaluate coherent  behavior of  vascular networks in the kidney, retina and brain;
  • we develop mechanism-based models and employ the concept of synchronization  to validate global dynamics of biological networks.