Fascination for Biosimulation and Functional Spectroscopy at BMI – Københavns Universitet

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14. december 2009

Fascination for Biosimulation and Functional Spectroscopy at BMI

Professor Olga Sosnovtseva's fascination for Biosimulation and Functional Spectroscopy (BioFunS) takes us back to Russia where Olga received her PhD in Physics and Mathematics (with specialization in Nonlinear Dynamics) in 1996. Since 2001 she has focused her research on simulation of cellular signaling and renal autoregulation. However, Olga has taken her research further and for the last three years she has participated in experimental research that applies laser interference microscopy and Raman spectroscopy to living cells.

Her profound absorption in her work is based in the excitement for the combination of innovative experimental techniques, new methods of data analysis and mechanism-based modeling of biological systems. With these techniques, methods and systems it is possible for Olga to work across different levels of structural organization: from cells, over tissues to the whole organ.

Research with results
Olga's research has resulted in different grants where the latest are:

2009-2013: Principal investigator in the grant Female Heads of Research from The Danish Council for Independent Research for the project In vivo Raman spectroscopy and mechanism-based modeling of erythrocyte properties: Revealing biomarkers of pathological conditions (5.757.120 DKK)

2007-2010: Skou Stipendium from The Danish Council for Independent Research for the project Mechanism-Based Modeling of Cellular Interactions: From Physics to Systems Biology (2.176.955 DKK)

2008-2010: Named participant in grant from The Danish Council for Independent Research for the project Cell-Cell Communication and Synchronization in the Renal Microvasculature in Normo- and Hypertensive Rats (2.168.400 DKK)

Olga goes to the Department of Biomedical Sciences
But the research has not only taken Olga from Russia to Denmark it has also taken her to BMI. Her decision to move to the department of Biomedical Sciences is a result of:

  • 1. Her eight years of collaboration with Prof. N.-H. Holstein-Rathlou in the area of renal physiology. The collaboration has resulted in 20 joint publications and two joint grants from The Lundbeck Foundation and The Danish Council for Independent Research;
  • 2. Recent results from the Renal and Vascular Research Section on application of laser speckle flowmetry to measurements of coherence between many nephrons which open new perspectives for research in the field;
  • 3. A recently established collaboration with Prof. Martin Lauritzen (Department of Neuroscience and Pharmacology, KU) in the area of neurovascular coupling which has resulted in two joint grant applications;
  • 4. The Department of Biomedical Sciences has excellent experimental facilities, which it offered to combine with Olga's experimental Raman spectroscopy set-up;
  • 5. The Department of Biomedical Sciences is a suitable environment for a new application to FP7 for continuation of the EU Network of Excellence: Biosimulation-A New Tool in Drug Development.

Finally, Olga placed her professional heart at BMI due to the fact that she finds that she will have excellent opportunities for professional development and for building a research group. 

If you have any questions or wish to know more about Professor Olga Sosnovtseva and her research, please do not hesitate to contact her.

Let us all give a warm welcome to Olga.